Vascular Pharmacology Cytoskeleton and Extracellular Matrix 1st edition by Raouf A Khalil ISBN 0128121513 978-0128121511

Vascular Pharmacology: Cytoskeleton and Extracellular Matrix 1st edition by Raouf A Khalil – Ebook PDF Instant Download/Delivery. 0128121513 978-0128121511
Full download Vascular Pharmacology: Cytoskeleton and Extracellular Matrix 1st edition after payment

Product details:

ISBN 10: 0128121513 
ISBN 13: 978-0128121511
Author:  Raouf A Khalil 

Vascular Pharmacology: Cytoskeleton and Extracellular Matrix, Volume 81, contains the latest information on the vascular cytoskeleton and extracellular matrix that is presented with helpful illustrations and supporting references by prominent scientists and highly-recognized experts in the vascular field. Topics of interest in this new release include Pharmacology of the Vascular Cytoskeleton and Extracellular Matrix, The Dynamic Actin Cytoskeleton in Smooth Muscle, The Role of the Actin Cytoskeleton in the Regulation of Vascular Inflammation, The Smoothelin Family of Proteins and the Smooth Muscle Cell Contractile Apparatus, Smooth Muscle Cytoskeletal Network Regulates Expression of the Profibrotic Genes PAI-1 and CTGF, and more.

• Presents a must-read book on the vascular cytoskeleton and extracellular matrix
• Contains up-to-date information on the structure, function and development of the vascular cell cytoskeleton
• Includes contributors from prominent scientists and highly-recognized experts with major accomplishments in the fields of the vascular cytoskeleton, extracellular matrix, mechanotransduction and vascular remodeling

Vascular Pharmacology: Cytoskeleton and Extracellular Matrix 1st Table of contents:

Chapter One: The Dynamic Actin Cytoskeleton in Smooth Muscle

Abstract

1 Introduction

2 Actin Dynamics and Smooth Muscle Contraction

3 Actin Dynamics and Smooth Muscle Cell Proliferation

4 Actin Dynamics and Smooth Muscle Cell Migration

5 Actin-Regulatory Proteins and Vascular/Pulmonary Diseases

6 Conclusion

Conflict of Interest

Acknowledgments

Chapter Two: Smoothelins and the Control of Muscle Contractility

Abstract

1 Introduction

2 The Smoothelin Family of Muscle Proteins

3 Molecular Evolution of SMTN Family Members

4 Functional Properties of Smoothelin Proteins

5 Physiological Impact of Smoothelins

6 Functional Properties of Smoothelin-Like 1

7 Physiological Relevance of Smoothelin-Like 1

8 Functional Properties of Smoothelin-Like 2

9 Clinical Relevance of Smoothelin Family Members

10 Conclusion

Conflict of Interest

Acknowledgments

Chapter Three: The Cytoskeletal Network Regulates Expression of the Profibrotic Genes PAI-1 and CTGF in Vascular Smooth Muscle Cells

Abstract

1 Introduction

2 Microtubule Disruption Induces PAI-1/CTGF Expression and src Kinase Activation

3 Transactivation of the Epidermal Growth Factor Receptor by Microtubule Disruption

4 MAP Kinase Pathways in VSMCs Function via pp60c-src/EGFR Signaling

5 SMAD2/3 Activation and PAI-1/CTGF Induction by Microtubule Alterations Requires Rho–ROCK Signaling

6 Conclusion

Conflict of Interest

Acknowledgment

Chapter Four: Basic Components of Vascular Connective Tissue and Extracellular Matrix

Abstract

1 Introduction

2 Tunica Intima

3 Tunica Media

4 Tunica Adventitia

5 Conclusion

Conflict of Interest Statement

Chapter Five: Integrins in Vascular Development and Pathology

Abstract

1 Introduction

2 Integrins in Vascular Development

3 Integrins in Vascular Pathology

4 Conclusion

Conflict of Interest Statement

Acknowledgments

Chapter Six: Mechanotransduction in Blood and Lymphatic Vascular Development and Disease

Abstract

1 Introduction

2 Blood Vasculature

3 Lymphatic Vasculature

4 Mechanotransduction in Blood and Lymphatic Vascular Disease

5 Conclusion

Conflict of Interest

Acknowledgments

Chapter Seven: Extracellular Matrix Macromolecules as Potential Targets of Cardiovascular Pharmacotherapy

Abstract

1 Introduction

2 ECM Macromolecules of Cardiovascular Tissue in Health and Disease

3 Effect of Current Cardiovascular Drugs on the ECM

4 Potential Future Pharmacotherapies Targeting the Cardiovascular ECM

5 Conclusion

Conflict of Interest

Acknowledgments

Chapter Eight: Matrix Metalloproteinases, Vascular Remodeling, and Vascular Disease

Abstract

1 Introduction

2 MMP Structure

3 Sources and Tissue Distribution of MMPs

4 MMP Activation

5 MMP Substrates

6 Tissue Inhibitors of Metalloproteinases

7 Other Biological and Pleiotropic MMP Inhibitors

8 Synthetic MMP Inhibitors

9 Role of MMPs in Vascular Biology

10 Role of MMPS in Vascular Pathology

11 Conclusion

Conflict of Interest

Acknowledgments

Chapter Nine: Mechanisms of I/R-Induced Endothelium-Dependent Vasodilator Dysfunction

Abstract

1 Introduction

2 Leukocyte-Mediated Postischemic Endothelial Dysfunction in Arterioles and Venules

3 LECA in Postcapillary Venules Is Required for the Development of Arteriolar EDD

4 Mediators Generated by the Proteolytic Activity of Emigrated Leukocytes Are Essential for the Development of EDD Dysfunction in I/R

5 Mast Cells Contribute to I/R-Induced Arteriolar EDD

6 ANG II-Dependent, NAD(P)H Oxidase-Mediated Production of ROS Contribute to eNOS Uncoupling and EDD in Arterioles After I/R

7 Conclusion

Conflict of Interest

Acknowledgments

Chapter Ten: The Role of Age-Related Intimal Remodeling and Stiffening in Atherosclerosis

Abstract

1 Introduction

2 Intimal ECM Remodeling and Stiffening

3 In Vivo Models of Arterial Stiffening

4 In Vitro Models of Arterial Stiffening

5 Endothelial Response to Arterial Stiffening

6 Conclusion

People also search for Vascular Pharmacology: Cytoskeleton and Extracellular Matrix 1st:

vascular pharmacology

vascular pharmacology impact factor

vascular pharmacology journal

cytoskeleton photos

a cytoskeleton