Ultrasound Elastography for Biomedical Applications and Medicine 1st edition by Ivan Nenadic, Matthew Urban, James Greenleaf, Jean Luc Gennisson, Miguel Bernal, Mickael Tanter ISBN 1119021510 978-1119021513

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ISBN 10:  1119021510 
ISBN 13: 978-1119021513
Author: Ivan Nenadic, Matthew  Urban, James Greenleaf, Jean Luc Gennisson, Miguel Bernal, Mickael Tanter

Ultrasound Elastography for Biomedical Applications and Medicine

Ivan Z. Nenadic, Matthew W. Urban, James F. Greenleaf, Mayo Clinic Ultrasound Research Laboratory, Mayo Clinic College of Medicine, USA

Jean-Luc Gennisson, Miguel Bernal, Mickael Tanter, Institut Langevin – Ondes et Images, ESPCI ParisTech CNRS, France

Covers all major developments and techniques of Ultrasound Elastography and biomedical applications

The field of ultrasound elastography has developed various techniques with the potential to diagnose and track the progression of diseases such as breast and thyroid cancer, liver and kidney fibrosis, congestive heart failure, and atherosclerosis. Having emerged in the last decade, ultrasound elastography is a medical imaging modality that can noninvasively measure and map the elastic and viscous properties of soft tissues.

Ultrasound Elastography for Biomedical Applications and Medicine covers the basic physics of ultrasound wave propagation and the interaction of ultrasound with various media. The book introduces tissue elastography, covers the history of the field, details the various methods that have been developed by research groups across the world, and describes its novel applications, particularly in shear wave elastography.

Key features:

• Covers all major developments and techniques of ultrasound elastography and biomedical applications.
• Contributions from the pioneers of the field secure the most complete coverage of ultrasound elastography available.

The book is essential reading for researchers and engineers working in ultrasound and elastography, as well as biomedical engineering students and those working in the field of biomechanics.

Ultrasound Elastography for Biomedical Applications and Medicine 1st Table of contents:

Section I: Introduction

1 Editors’ Introduction

References

Section II: Fundamentals of Ultrasound Elastography

2 Theory of Ultrasound Physics and Imaging

2.1 Introduction

2.2 Modeling the Response of the Source to Stimuli [ ]

2.3 Modeling the Fields from Sources [ ]

2.4 Modeling an Ultrasonic Scattered Field [ ]

2.5 Modeling the Bulk Properties of the Medium [ ]

2.6 Processing Approaches Derived from the Physics of Ultrasound [Ω]

2.7 Conclusions

References

3 Elastography and the Continuum of Tissue Response

3.1 Introduction

3.2 Some Classical Solutions

3.3 The Continuum Approach

3.4 Conclusion

Acknowledgments

References

4 Ultrasonic Methods for Assessment of Tissue Motion in Elastography

4.1 Introduction

4.2 Basic Concepts and their Relevance in Tissue Motion Tracking

4.3 Tracking Tissue Motion through Frequency‐domain Methods

4.4 Maximum Likelihood (ML) Time‐domain Correlation‐based Methods

4.5 Tracking Tissue Motion through Combining Time‐domain and Frequency‐domain Information

4.6 Time‐domain Maximum A Posterior (MAP) Speckle Tracking Methods

4.7. Optical Flow‐based Tissue Motion Tracking

4.8 Deformable Mesh‐based Motion‐tracking Methods

4.9 Future Outlook

4.10 Conclusions

Acknowledgments

Acronyms

Additional Nomenclature of Definitions and Acronyms

References

Section III: Theory of Mechanical Properties of Tissue

5 Continuum Mechanics Tensor Calculus and Solutions to Wave Equations

5.1 Introduction

5.2 Mathematical Basis and Notation

5.3 Solutions to Wave Equations

References

6 Transverse Wave Propagation in Anisotropic Media

6.1 Introduction

6.2 Theoretical Considerations from General to Transverse Isotropic Models for Soft Tissues

6.3 Experimental Assessment of Anisotropic Ratio by Shear Wave Elastography

6.4 Conclusion

References

7 Transverse Wave Propagation in Bounded Media

7.1 Introduction

7.2 Transverse Wave Propagation in Isotropic Elastic Plates

7.3 Plate in Vacuum: Lamb Waves

7.4 Viscoelastic Plate in Liquid: Leaky Lamb Waves

7.5 Isotropic Plate Embedded Between Two Semi‐infinite Elastic Solids

7.6 Transverse Wave Propagation in Anisotropic Viscoelastic Plates Surrounded by Non‐viscous Fluid

7.7 Conclusions

Acknowledgments

References

8 Rheological Model‐based Methods for Estimating Tissue Viscoelasticity

8.1 Introduction

8.2 Shear Modulus and Rheological Models

8.3 Applications of Rheological Models

References

9 Wave Propagation in Viscoelastic Materials

9.1 Introduction

9.2 Estimating the Complex Shear Modulus from Propagating Waves

9.3 Wave Generation and Propagation

9.4 Rheological Models

9.5 Experimental Results and Applications

9.6 Summary

References

Section IV: Static and Low Frequency Elastography

10 Validation of Quantitative Linear and Nonlinear Compression Elastography

10.1 Introduction

10.2 Methods

10.3 Results

10.4 Discussion

10.5 Conclusions

Acknowledgement

References

11 Cardiac Strain and Strain Rate Imaging

11.1 Introduction

11.2 Strain Definitions in Cardiology

11.3 Methodologies Towards Cardiac Strain (Rate) Estimation

11.4 Experimental Validation of the Proposed Methodologies

11.5 Clinical Applications

11.6 Future Developments

References

12 Vascular and Intravascular Elastography

12.1 Introduction

12.2 General Principles

12.3 Conclusion

References

13 Viscoelastic Creep Imaging

13.1 Introduction

13.2 Overview of Governing Principles

13.3 Imaging Techniques

13.4 Conclusion

References

14 Intrinsic Cardiovascular Wave and Strain Imaging

14.1 Introduction

14.2 Cardiac Imaging

14.3 Vascular Imaging

Acknowledgements

References

Section V: Harmonic Elastography Methods

15 Dynamic Elasticity Imaging

15.1 Vibration Amplitude Sonoelastography: Early Results

15.2 Sonoelastic Theory

15.3 Vibration Phase Gradient Sonoelastography

15.4 Crawling Waves

15.5 Clinical Results

15.6 Conclusion

Acknowledgments

References

16 Harmonic Shear Wave Elastography

16.1 Introduction

16.2 Basic Principles

16.3 Ex Vivo Validation

16.4 In Vivo Application

16.5 Summary

Acknowledgments

References

17 Vibro‐acoustography and its Medical Applications

17.1 Introduction

17.2 Background

17.3 Application of Vibro‐acoustography for Detection of Calcifications

17.4 In Vivo Breast Vibro‐acoustography

17.5 In Vivo Thyroid Vibro‐acoustography

17.6 Limitations and Further Future Plans

Acknowledgments

References

18 Harmonic Motion Imaging

18.1 Introduction

18.2 Background

18.3 Methods

18.4 Preclinical Studies

18.5 Future Prospects

Acknowledgements

References

19 Shear Wave Dispersion Ultrasound Vibrometry

19.1 Introduction

19.2 Principles of Shear Wave Dispersion Ultrasound Vibrometry (SDUV)

19.3 Clinical Applications

19.4 Summary

References

Section VI: Transient Elastography Methods

20 Transient Elastography: From Research to Noninvasive Assessment of Liver Fibrosis Using Fibroscan®

20.1 Introduction

20.2 Principles of Transient Elastography

20.3 Fibroscan

20.4 Application of Vibration‐controlled Transient Elastography to Liver Diseases

20.5 Other Applications of Transient Elastography

20.6 Conclusion

References

21 From Time Reversal to Natural Shear Wave Imaging

21.1 Introduction: Time Reversal Shear Wave in Soft Solids

21.2 Shear Wave Elastography using Correlation: Principle and Simulation Results

21.3 Experimental Validation in Controlled Media

21.4 Natural Shear Wave Elastography: First In Vivo Results in the Liver, the Thyroid, and the Brain

21.5 Conclusion

References

22 Acoustic Radiation Force Impulse Ultrasound

22.1 Introduction

22.2 Impulsive Acoustic Radiation Force

22.3 Monitoring ARFI‐induced Tissue Motion

22.4 ARFI Data Acquisition

22.5 ARFI Image Formation

22.6 Real‐time ARFI Imaging

22.7 Quantitative ARFI Imaging

22.8 ARFI Imaging in Clinical Applications

22.9 Commercial Implementation

22.10 Related Technologies

22.11 Conclusions

References

23 Supersonic Shear Imaging

23.1 Introduction

23.2 Radiation Force Excitation

23.3 Ultrafast Imaging

23.4 Shear Wave Speed Mapping

23.5 Conclusion

References

24 Single Tracking Location Shear Wave Elastography

24.1 Introduction

24.2 SMURF

24.3 STL‐SWEI

24.4 Noise in SWE/Speckle Bias

24.5 Estimation of viscoelastic parameters (STL‐VE)

24.6 Conclusion

References

25 Comb‐push Ultrasound Shear Elastography

25.1 Introduction

25.2 Principles of Comb‐push Ultrasound Shear Elastography (CUSE)

25.3 Clinical Applications of CUSE

25.4 Summary

References

Section VII: Emerging Research Areas in Ultrasound Elastography

26 Anisotropic Shear Wave Elastography

26.1 Introduction

26.2 Shear Wave Propagation in Anisotropic Media

26.3 Anisotropic Shear Wave Elastography Applications

26.4 Conclusion

References

27 Application of Guided Waves for Quantifying Elasticity and Viscoelasticity of Boundary Sensitive Organs

27.1 Introduction

27.2 Myocardium

27.3 Arteries

27.4 Urinary Bladder

27.5 Cornea

27.6 Tendons

27.7 Conclusions

References

28 Model‐free Techniques for Estimating Tissue Viscoelasticity

28.1 Introduction

28.2 Overview of Governing Principles

28.3 Imaging Techniques

28.4 Conclusion

References

29 Nonlinear Shear Elasticity

29.1 Introduction

29.2 Shocked Plane Shear Waves

29.3 Nonlinear Interaction of Plane Shear Waves

29.4 Acoustoelasticity Theory

29.5 Assessment of 4th Order Nonlinear Shear Parameter

29.6 Conclusion

References

Section VIII: Clinical Elastography Applications

30 Current and Future Clinical Applications of Elasticity Imaging Techniques

30.1 Introduction

30.2 Clinical Implementation and Use of Elastography

30.3 Clinical Applications

30.4 Future Work in Clinical Applications of Elastography

30.5 Conclusions

Acknowledgments

References

31 Abdominal Applications of Shear Wave Ultrasound Vibrometry and Supersonic Shear Imaging

31.1 Introduction

31.2 Liver Application

31.3 Prostate Application

31.4 Kidney Application

31.5 Intestine Application

31.6 Uterine Cervix Application

31.7 Spleen Application

31.8 Pancreas Application

31.9 Bladder Application

31.10 Summary

References

32 Acoustic Radiation Force‐based Ultrasound Elastography for Cardiac Imaging Applications

32.1 Introduction

32.2 Acoustic Radiation Force‐based Elastography Techniques

32.3 ARF‐based Elasticity Assessment of Cardiac Function

32.4 ARF‐based Image Guidance for Cardiac Radiofrequency Ablation Procedures

32.5 Conclusions

Funding Acknowledgements

References

33 Cardiovascular Application of Shear Wave Elastography

33.1 Introduction

33.2 Cardiovascular Shear Wave Imaging Techniques

33.3 Clinical Applications of Cardiovascular Shear Wave Elastography

33.4 Summary

References

34 Musculoskeletal Applications of Supersonic Shear Imaging

34.1 Introduction

34.2 Muscle Stiffness at Rest and During Passive Stretching

34.3 Active and Dynamic Muscle Stiffness

34.4 Tendon Applications

34.5 Clinical Applications

34.6 Future Directions

References

35 Breast Shear Wave Elastography

35.1 Introduction

35.2 Background

35.3 Breast Elastography Techniques

35.4 Application of CUSE for Breast Cancer Detection

35.5 CUSE on a Clinical Ultrasound Scanner

35.6 Limitations of Breast Shear Wave Elastography

35.7 Conclusion

Acknowledgments

References

36 Thyroid Shear Wave Elastography

36.1 Introduction

36.2 Background

36.3 Role of Ultrasound and its Limitation in Thyroid Cancer Detection

36.4 Fine Needle Aspiration Biopsy (FNAB)

36.5 The Role of Elasticity Imaging

36.6 Application of CUSE on Thyroid

36.7 CUSE on Clinical Ultrasound Scanner

36.8 Conclusion

Acknowledgments

References

Section IX: Perspective on Ultrasound Elastography

37 Historical Growth of Ultrasound Elastography and Directions for the Future

37.1 Introduction

37.2 Elastography Publication Analysis

37.3 Future Investigations of Acoustic Radiation Force for Elastography

37.4 Conclusions

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