The Lipid Handbook with CD ROM 3rd Edition by Frank Gunstone, John Harwood, Albert Dijkstra ISBN 0849396883 9780849396885

Extensively revised, reorganized, and expanded, the third edition of the industry standard, The Lipid Handbook reflects many of the changes in lipid science and technology that have occurred in the last decade. All chapters have been rewritten, many by new authors, to match the updated thinking and practice of modern lipid science and bring a fresh perspective to twenty years of tradition.

Retaining the general structure of the previous editions, The Lipid Handbook with CD-ROM, Third Edition collates a wide range of information into a single volume. New contributions highlight the latest technologies utilized in today’s lipid science such as chromatographic analysis and nuclear magnetic resonance spectroscopy. An entirely new chapter is devoted to non-food uses such as lipids as surfactants, cosmetics, and biofuels. Expanded sections illustrate a growing emphasis on lipid metabolism and the nutritional, medical, and agricultural aspects including human dietary requirements and disorders of lipid metabolism. The dictionary section is vastly expanded to cover chemical structure, physical properties, and references to thousands of lipid and lipid related molecules. The handbook now includes a CD-ROM that allows instant access to tabulated and referenced information and can be searched either as the full text or by structure or substructure.

Drawing from the best minds in the field, The Lipid Handbook with CD-ROM, Third Edition presents the latest technological developments and the current and future directions and applications of lipid science to the next generation of researchers.

The Lipid Handbook with CD ROM 3rd Edition Table of contents:

Section I: Introduction to Lipids

1. What are Lipids?
   • Definition and Classification of Lipids
   • Basic Lipid Structures
   • Lipid Classification Systems
   • Roles of Lipids in Biological Systems
2. History and Development of Lipid Research
   • Early Discoveries
   • Advances in Lipid Chemistry and Biology
   • The Role of Lipids in Medicine and Industry

Section II: Lipid Structure and Chemistry 3. Fatty Acids

• Structure and Nomenclature
• Saturated and Unsaturated Fatty Acids
• Fatty Acid Synthesis and Metabolism
• Essential Fatty Acids and Their Biological Roles

4. Glycerolipids
   • Phospholipids
   • Glycolipids
   • Triacylglycerols (Triglycerides)
   • Their Biological Functions
5. Sphingolipids
   • Sphingosine and Its Derivatives
   • Sphingomyelins and Glycosphingolipids
   • Their Roles in Cell Signaling and Membranes
6. Sterols and Steroids
   • Structure of Cholesterol and Other Sterols
   • Synthesis and Metabolism of Steroids
   • Biological Roles of Cholesterol and Steroids
7. Other Lipids
   • Prenol Lipids
   • Isoprenoids and Their Derivatives
   • Eicosanoids: Prostaglandins, Leukotrienes, and Thromboxanes

Section III: Lipid Metabolism 8. Lipid Digestion and Absorption

• Digestive Enzymes and Lipid Breakdown
• Lipid Transport in the Bloodstream
• Absorption in the Intestine

9. Lipid Synthesis
   • Biosynthesis of Fatty Acids and Triacylglycerols
   • Glycerophospholipid Synthesis
   • Steroid and Sphingolipid Biosynthesis
10. Lipid Catabolism
    • Beta-Oxidation of Fatty Acids
    • Ketogenesis and Its Regulation
    • Degradation of Phospholipids and Sphingolipids

Section IV: Lipid Functions and Biological Roles 11. Lipids in Cell Membranes – Membrane Lipid Composition – Fluidity and Function of Biological Membranes – Membrane Lipid Asymmetry and Lipid Rafts 12. Lipids as Energy Storage – Triacylglycerol Storage in Adipocytes – Mobilization of Stored Fat – Lipids and Energy Metabolism 13. Signaling and Regulation – Lipid Signaling Molecules: Eicosanoids and Others – Phosphoinositides and Cellular Signaling – Lipid-Based Hormones and Their Actions

Section V: Lipids in Health and Disease 14. Lipids in Cardiovascular Disease – Cholesterol and Lipoproteins – Role of Lipids in Atherosclerosis – Dietary Lipids and Heart Disease 15. Obesity and Diabetes – Lipid Metabolism and Insulin Resistance – Role of Lipids in Adipose Tissue Function – Impact of Dietary Fat on Obesity and Diabetes 16. Neurobiology of Lipids – Lipids in the Nervous System – Myelin Sheath and Neuronal Lipid Composition – Lipid-Mediated Signaling in Brain Function 17. Lipids in Inflammation – Eicosanoids and Their Role in Inflammation – Lipid Mediators of Immune Response – Therapeutic Targets for Lipid-Mediated Inflammation

Section VI: Lipids in Food and Industry 18. Lipids in Food – Dietary Lipids: Sources and Composition – Fatty Acids and Human Nutrition – Cooking, Processing, and Health Implications 19. Lipid Biotechnology – Lipids in Cosmetics and Pharmaceuticals – Bioactive Lipids and Their Applications – Lipid-Based Drug Delivery Systems 20. Industrial Applications of Lipids – Lipids in Biodiesel Production – Use of Lipids in Detergents and Surfactants – Industrial and Agricultural Lipid Products

Section VII: Analytical Methods for Lipids 21. Lipid Analysis: Basic Techniques – Thin Layer Chromatography (TLC) – Gas Chromatography (GC) – High-Performance Liquid Chromatography (HPLC) – Mass Spectrometry for Lipid Analysis 22. Advanced Analytical Methods – Nuclear Magnetic Resonance (NMR) Spectroscopy – Lipidomics and Quantitative Analysis – New Frontiers in Lipid Research: Technologies and Trends

Appendices

• Appendix A: Glossary of Terms
• Appendix B: Conversion Tables
• Appendix C: List of Abbreviations

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