Textbook of Medical Biochemistry 8th Edition by MN Chatterjea, Rana Shinde, Venkatesh, Vijaykant Kambli, Sita Devi ISBN 9350254840 9789350254844

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Product details:
ISBN 10: 9350254840
ISBN 13: 9789350254844
Author: MN Chatterjea, Rana Shinde, Venkatesh, Vijaykant Kambli, Sita Devi

Textbook of Medical Biochemistry 8th Edition Table of contents:

1. Introduction to Medical Biochemistry

• Overview of Biochemistry in Medicine
• The Role of Biochemistry in Clinical Practice
• Key Principles of Biochemistry
• Chemical Basis of Life: Elements and Biomolecules
• Water, pH, and Buffers in Biological Systems

2. Structure and Function of Biomolecules

• Carbohydrates: Classification, Structure, and Functions
• Proteins: Amino Acids, Peptides, and Protein Structure
• Enzymes: Mechanism of Action, Kinetics, and Regulation
• Nucleic Acids: DNA, RNA, and Their Functions
• Lipids: Types, Structure, and Biological Importance

3. Enzyme Kinetics and Regulation

• Enzyme Catalysis and Mechanisms
• Factors Affecting Enzyme Activity
• Inhibition of Enzyme Activity
• Allosteric Regulation of Enzymes
• Isozymes and Their Clinical Relevance

4. Metabolism of Carbohydrates

• Glycolysis: Pathway, Regulation, and Energetics
• Gluconeogenesis: Mechanisms and Regulation
• Glycogen Metabolism: Synthesis and Breakdown
• Pentose Phosphate Pathway
• Clinical Disorders of Carbohydrate Metabolism

5. Metabolism of Lipids

• Digestion and Absorption of Lipids
• Fatty Acid Metabolism: Beta-Oxidation and Biosynthesis
• Cholesterol Metabolism and Its Regulation
• Lipoproteins and Their Role in Transport
• Disorders of Lipid Metabolism

6. Protein Metabolism

• Amino Acid Metabolism: Transamination, Deamination, and Urea Cycle
• Synthesis of Non-Essential Amino Acids
• Metabolism of Special Amino Acids: Creatine, Glutamine
• Disorders of Protein Metabolism
• Clinical Applications: Hyperammonemia and Other Disorders

7. Nucleic Acid Metabolism

• Purine and Pyrimidine Metabolism
• Synthesis and Breakdown of Nucleotides
• DNA Replication and Repair Mechanisms
• RNA Synthesis and Regulation
• Disorders in Nucleic Acid Metabolism

8. Bioenergetics and Cellular Metabolism

• Thermodynamics of Biochemical Reactions
• ATP Synthesis: Glycolysis, TCA Cycle, Oxidative Phosphorylation
• Coupling of Catabolic and Anabolic Pathways
• Mitochondrial Function and Energy Production
• Metabolic Control and Integration

9. Hormonal Regulation of Metabolism

• Endocrine Control of Metabolic Pathways
• Insulin and Glucagon in Carbohydrate and Fat Metabolism
• Cortisol, Growth Hormone, and Thyroid Hormones
• Sex Hormones and Their Effects on Metabolism
• Diabetes Mellitus: Biochemical Basis and Metabolic Implications

10. Biochemical Basis of Diseases

• Metabolic Disorders: Inborn Errors of Metabolism
• Genetic Disorders Affecting Metabolism: Phenylketonuria, Alkaptonuria
• Disorders of Lipid Metabolism: Hyperlipidemia, Atherosclerosis
• Disorders of Carbohydrate Metabolism: Diabetes, Glycogen Storage Diseases
• Cancer Metabolism and the Warburg Effect

11. Clinical Biochemistry and Diagnostic Applications

• Diagnostic Use of Biochemical Tests
• Blood Chemistry and Electrolytes
• Liver Function Tests and Renal Function Tests
• Biochemical Markers in Cardiovascular Diseases
• Use of Enzymes as Diagnostic Tools

12. Molecular Biology and Genetic Engineering

• DNA Technology and Its Applications in Medicine
• Polymerase Chain Reaction (PCR) and Its Clinical Uses
• Recombinant DNA and Protein Engineering
• Gene Therapy and Biotechnological Applications
• Molecular Diagnostics and Personalized Medicine

13. Nutritional Biochemistry

• The Role of Vitamins and Minerals in Metabolism
• Nutrients in Disease Prevention: Antioxidants, Fiber
• Biochemical Basis of Malnutrition
• Obesity: Biochemical Mechanisms and Implications
• Nutrition and Metabolic Disorders

14. Biochemical Techniques

• Principles of Biochemical Laboratory Techniques
• Chromatography, Electrophoresis, and Spectrophotometry
• Enzyme-Linked Immunosorbent Assay (ELISA) and Other Diagnostic Methods
• Mass Spectrometry in Biochemistry
• Genetic Testing and Analysis Techniques

15. Recent Advances in Medical Biochemistry

• Advances in Molecular Medicine and Biotechnology
• Metabolomics and Its Role in Disease Diagnosis
• Biochemical Research in Cancer Treatment
• Stem Cell Therapy and Regenerative Medicine
• Personalized Medicine and Pharmacogenomics

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