Textbook of Medical Biochemistry 8th Edition by Chatterjea, Rana Shinde, Venkatesh, Vijaykant Kambli, Sita Devi ISBN 9350254840 9789350254844

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Product details:
ISBN 10: 9350254840
ISBN 13: 9789350254844
Author: Chatterjea, Rana Shinde, Venkatesh, Vijaykant Kambli, Sita Devi

Textbook of Medical Biochemistry 8th Edition Table of contents:

Part 1: Biochemistry and Molecular Biology Fundamentals

1. Introduction to Biochemistry

   • Definition and Scope of Biochemistry
   • Role of Biochemistry in Medicine
   • Methods in Biochemical Research

2. Structure of Biomolecules

   • Water and Its Biological Importance
   • Amino Acids and Peptides
   • Proteins: Structure, Function, and Enzyme Kinetics
   • Carbohydrates: Monosaccharides, Disaccharides, and Polysaccharides
   • Lipids: Fatty Acids, Triglycerides, Phospholipids, and Steroids
   • Nucleic Acids: DNA and RNA Structure and Function

3. Enzyme Kinetics and Regulation

   • Principles of Enzyme Action
   • Enzyme Classification and Mechanism
   • Enzyme Inhibition and Regulation
   • Isozymes and Coenzymes

4. Cellular Structure and Function

   • Cell Membranes and Organelles
   • Transport Mechanisms Across Membranes
   • Cell Signaling and Second Messengers

Part 2: Metabolism of Carbohydrates, Lipids, and Proteins

5. Carbohydrate Metabolism

   • Glycolysis and Gluconeogenesis
   • Citric Acid Cycle (Krebs Cycle)
   • Glycogen Metabolism
   • Pentose Phosphate Pathway
   • Regulation of Blood Glucose

6. Lipid Metabolism

   • Fatty Acid Metabolism and β-Oxidation
   • Synthesis of Fatty Acids and Triacylglycerols
   • Cholesterol Metabolism and Regulation
   • Ketone Bodies: Formation and Utilization

7. Protein Metabolism

   • Amino Acid Metabolism and Urea Cycle
   • Protein Synthesis and Breakdown
   • Metabolism of Individual Amino Acids
   • Nitrogen Balance and Disorders

8. Integration of Metabolism

   • Hormonal Regulation of Metabolism
   • Energy Metabolism in Different Tissues
   • Metabolic Adaptations During Fasting and Exercise

Part 3: Vitamins, Minerals, and Molecular Genetics

9. Vitamins and Coenzymes

   • Water-Soluble Vitamins (B-Vitamins and Vitamin C)
   • Fat-Soluble Vitamins (A, D, E, and K)
   • Role of Coenzymes in Metabolism
   • Deficiencies and Clinical Relevance

10. Mineral Metabolism

    • Essential Minerals: Sodium, Potassium, Calcium, Magnesium
    • Trace Elements: Iron, Zinc, Copper, Iodine
    • Electrolyte Balance and Its Disorders

11. Molecular Genetics and Biotechnology

    • DNA Replication, Repair, and Recombination
    • Transcription and Translation Mechanisms
    • Regulation of Gene Expression
    • Applications of Biotechnology in Medicine

Part 4: Biochemical Basis of Disease

12. Inborn Errors of Metabolism

    • Disorders of Carbohydrate, Protein, and Lipid Metabolism
    • Enzyme Deficiencies and Genetic Diseases
    • Screening for Inborn Errors of Metabolism

13. Endocrine Disorders and Metabolic Syndrome

    • Diabetes Mellitus: Types and Metabolic Pathways
    • Hypothyroidism and Hyperthyroidism
    • Obesity and Metabolic Syndrome

14. Neurochemistry

    • Neurotransmitters and Their Roles
    • Biochemistry of the Brain and Nervous System
    • Biochemical Basis of Neurodegenerative Disorders

15. Cancer Biochemistry

    • Oncogenes and Tumor Suppressor Genes
    • Biochemical Mechanisms in Cancer Development
    • Molecular Targets for Cancer Therapy

16. Cardiovascular and Renal Disorders

    • Biochemistry of Atherosclerosis and Heart Disease
    • Renal Function and Biochemical Markers
    • Disorders of Electrolyte and Fluid Balance

Part 5: Clinical Biochemistry

17. Clinical Chemistry and Laboratory Diagnostics

    • Blood Biochemistry and Routine Tests
    • Liver, Kidney, and Cardiac Biomarkers
    • Interpretation of Lab Results in Disease Diagnosis

18. Biochemistry of Infectious Diseases

    • Biochemical Pathways of Bacterial, Viral, and Fungal Infections
    • Diagnostic Biochemistry in Infectious Diseases

19. Pharmacology and Biochemistry

    • Mechanisms of Drug Action at the Molecular Level
    • Biochemistry of Drug Metabolism
    • Pharmacogenomics and Personalized Medicine

Part 6: Advanced Topics in Medical Biochemistry

20. Advanced Biochemical Techniques

    • Chromatography and Electrophoresis
    • Mass Spectrometry and Protein Analysis
    • Molecular Cloning and PCR

21. Biochemistry of Aging

    • Free Radicals and Antioxidant Defense
    • Metabolic Changes with Aging
    • Age-Related Diseases and Biochemistry

22. Nutritional Biochemistry

    • Role of Nutrients in Health and Disease
    • Malnutrition and Its Biochemical Consequences
    • Clinical Nutrition and Therapeutic Diets

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