Sudden Cardiac Death in the Young Athletes Text Atlas of Pathology and Clinical Correlates 1st edition by Gaetano Thiene, Domenico Corrado, Cristina Basso ISBN 8847057752 978-8847057753

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ISBN 10: 8847057752 
ISBN 13: 978-8847057753
Author:   Gaetano Thiene, Domenico Corrado, Cristina Basso 

This text atlas focuses on the pathology and molecular genetics of sudden cardiac death in the young and in athletes, presenting the state of the art in the field as the basis for development and implementation of more effective prevention strategies, including, ultimately, molecular therapy that will cure the underlying biological defect. A wealth of high-resolution color images, accompanied by clear supporting text, are presented to document the anatomic pathology of the cardiac diseases most frequently responsible for sudden cardiac death in this population, including coronary artery diseases, cardiomyopathies, myocarditis, valve diseases, conduction system abnormalities, congenital heart diseases, and ion channel diseases. The role of the molecular autopsy in overcoming the limitations of morphological investigations and offering new insights and avenues for prevention is explained. The approach is, however, interdisciplinary, with close attention also to epidemiologic and clinical aspects. The authors draw throughout on their experience gained over 30 years in the course of a prospective study carried out in the Veneto Region, North East Italy. This text atlas will be of great value not only for cardiologists but also for geneticists, sports physicians, and residents in cardiology and pathology.

Sudden Cardiac Death in the Young  Athletes Text Atlas of Pathology and Clinical Correlates 1st Table of contents:

• Introduction to Sudden Cardiac Death in Athletes

  • Definition of sudden cardiac death (SCD) in young athletes
  • Overview of its incidence and importance in sports medicine
  • Key risk factors for SCD in athletes

• Anatomy and Pathology of the Heart

  • Normal cardiac anatomy and function in athletes
  • Pathophysiological changes in the heart due to intense physical activity
  • Structural and functional abnormalities leading to SCD

• Genetic and Hereditary Disorders

  • Inherited arrhythmic syndromes (e.g., Long QT syndrome, Brugada syndrome)
  • Hypertrophic cardiomyopathy and dilated cardiomyopathy in athletes
  • Familial and genetic risk factors for SCD in the young

• Common Cardiac Pathologies Linked to SCD

  • Coronary artery anomalies and their role in SCD
  • Myocarditis and its implications for sudden death in athletes
  • Arrhythmogenic right ventricular dysplasia (ARVD) and its pathogenesis

• Pathology of Myocardial and Vascular Diseases

  • Coronary artery disease in young athletes
  • Non-atherosclerotic causes of SCD (e.g., myocardial infarction, thrombosis)
  • Structural heart abnormalities leading to arrhythmias

• Autopsy Findings in Sudden Cardiac Death

  • The role of postmortem examination in determining cause of death
  • Histopathological features in athletes who suffer from SCD
  • Distinguishing between different causes of death through autopsy

• Clinical Presentation and Diagnosis

  • Symptoms and warning signs of potential cardiac events in athletes
  • Screening and diagnostic tests (e.g., ECG, echocardiography, stress testing)
  • Clinical management and monitoring of athletes with heart conditions

• Preventive Measures and Risk Screening

  • Strategies for identifying at-risk athletes
  • Pre-participation screening protocols for athletes
  • Role of the family history and physical examination in screening

• Management of Cardiac Events During Athletic Activity

  • Immediate management of athletes experiencing cardiac arrest during sports
  • Use of automated external defibrillators (AEDs) in sports settings
  • Cardiopulmonary resuscitation (CPR) guidelines for athletes

• Ethical, Legal, and Social Considerations

  • Ethical issues in screening and disqualifying athletes
  • Legal implications of SCD in young athletes
  • The role of sports organizations in managing cardiac risks

• Case Studies and Clinical Correlates

  • Real-life case studies of young athletes who experienced sudden cardiac death
  • Clinical correlations and lessons learned from these cases
  • Interdisciplinary management and follow-up care for athletes at risk

• Emerging Research and Future Directions

  • Advances in genetics and molecular pathology in SCD
  • New technologies for detecting cardiac risks in athletes
  • Future research in preventing and managing SCD in the young

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