Sudden Cardiac Death in the Young and Athletes Text Atlas of Pathology and Clinical Correlates 1st edition by Gaetano Thiene, Domenico Corrado, Cristina Basso ISBN 8847057752 978-8847057753

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ISBN 10:  8847057752 
ISBN 13:  978-8847057753
Author: Gaetano Thiene, Domenico Corrado, Cristina Basso 

This text atlas focuses on the pathology and molecular genetics of sudden cardiac death in the young and in athletes, presenting the state of the art in the field as the basis for development and implementation of more effective prevention strategies, including, ultimately, molecular therapy that will cure the underlying biological defect. A wealth of high-resolution color images, accompanied by clear supporting text, are presented to document the anatomic pathology of the cardiac diseases most frequently responsible for sudden cardiac death in this population, including coronary artery diseases, cardiomyopathies, myocarditis, valve diseases, conduction system abnormalities, congenital heart diseases, and ion channel diseases. The role of the molecular autopsy in overcoming the limitations of morphological investigations and offering new insights and avenues for prevention is explained. The approach is, however, interdisciplinary, with close attention also to epidemiologic and clinical aspects. The authors draw throughout on their experience gained over 30 years in the course of a prospective study carried out in the Veneto Region, North East Italy. This text atlas will be of great value not only for cardiologists but also for geneticists, sports physicians, and residents in cardiology and pathology.

Sudden Cardiac Death in the Young and Athletes Text Atlas of Pathology and Clinical Correlates 1st Table of contents:

1. Introduction
   • Overview of Sudden Cardiac Death in the Young and Athletes
   • Epidemiology and Clinical Significance
   • Mechanisms and Risk Factors for Sudden Cardiac Death
   • Pathophysiology and Causes in the Young and Athletes
2. Pathology of Sudden Cardiac Death
   • Structural Heart Disease and SCD
   • Congenital Heart Defects and Arrhythmogenic Syndromes
   • Myocardial Diseases Leading to SCD
   • Ischemic Heart Disease in the Young
   • Cardiomyopathies: Hypertrophic, Dilated, and Arrhythmogenic Right Ventricular
   • Inflammatory Heart Diseases and SCD
   • Coronary Artery Anomalies and SCD
3. Electrophysiological Mechanisms of Sudden Cardiac Death
   • Arrhythmias and Their Role in SCD
   • Ventricular Arrhythmias and Their Pathology
   • Genetic Basis of Arrhythmias
   • Long QT Syndrome and Other Genetic Arrhythmogenic Syndromes
   • Channelopathies and SCD
4. Clinical Presentation and Diagnosis
   • Clinical Features of Sudden Cardiac Death in Young Athletes
   • Autopsy Findings in Sudden Cardiac Death
   • Diagnostic Techniques: ECG, Echocardiography, MRI, and Genetic Testing
   • Screening Methods for Athletes and High-Risk Individuals
   • The Role of Family History and Genetic Testing in Diagnosis
5. Sudden Cardiac Death in Young Athletes
   • Athlete’s Heart vs. Pathological Conditions
   • Risk Factors for SCD in Athletes
   • Sports-Related Sudden Cardiac Death: Epidemiology and Trends
   • Prevention, Screening, and Management in Athletes
   • The Role of Exercise and Physical Activity in Cardiac Risk
6. Genetic and Inherited Cardiac Diseases
   • Inherited Cardiomyopathies and Their Role in SCD
   • Channelopathies: Genetics and Clinical Implications
   • Genetic Testing and Risk Stratification
   • The Role of Genetic Counseling and Family Screening
   • Ethical Issues in Genetic Testing for SCD Risk
7. Forensic Pathology of Sudden Cardiac Death
   • Forensic Considerations in Autopsy of Sudden Cardiac Death Cases
   • Postmortem Findings and Their Interpretation
   • Challenges in Diagnosing the Cause of Sudden Cardiac Death
   • Role of the Pathologist in SCD Cases
8. Preventive Measures and Interventions
   • Screening Programs for High-Risk Individuals
   • Implantable Cardioverter Defibrillators (ICDs) in High-Risk Patients
   • Cardiovascular Risk Reduction Strategies in Young Athletes
   • Lifestyle Modifications and Management of Preexisting Cardiac Conditions
   • The Role of Public Awareness and Education
9. Management of Sudden Cardiac Death Events
   • Immediate Management of SCD Events in Athletes
   • Advanced Cardiovascular Life Support (ACLS) Protocols
   • Post-SCD Management: Rehabilitation and Psychological Support
   • Legal and Ethical Issues in the Management of Athletes with Cardiac Risk
10. Case Studies and Clinical Correlates

• Real-World Case Studies of Sudden Cardiac Death in Young Individuals and Athletes
• Pathological and Clinical Correlations: Case-by-Case Analysis
• Lessons Learned and Key Takeaways

11. Conclusion

• Summary of Key Findings and Insights
• Future Directions in Research and Prevention
• Emerging Trends in Sudden Cardiac Death Risk Management

12. Appendices

• Glossary of Terms
• Key Diagnostic Criteria for SCD
• References and Further Reading

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