Sleep Wake Neurobiology and Pharmacology 1st edition by Hans Peter Landolt,Derk Jan Dijk 9783030112721 3030112721

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Product details: 

ISBN 10: 3030112721

ISBN 13: 9783030112721

Author:Hans Peter Landolt,Derk Jan Dijk

This volume connects current ideas and concepts about sleep functions and circadian rhythms with the search for novel target-selective sleep-wake therapeutics. To do so, it provides a timely, state-of-the-art overview of sleep-wake mechanisms in health and disease, ongoing developments in drug discovery, and their prospects for the clinical treatment of sleep-disordered patients. It particularly focuses on the concept that sleep and wakefulness mutually affect each other, and the future therapeutic interventions with either sleep- or wake-promoting agents that are expected to not only improve the quality of sleep but also the waking behavior, cognition, mood and other sleep-associated physiological functions. The chapter ‘Sleep Physiology, Circadian Rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics’ available open access under a CC BY 4.0 license at link.springer.com

Sleep Wake Neurobiology and Pharmacology 1st Table of contents: 

The Function(s) of Sleep
Neuroanatomical and Neurochemical Bases of Vigilance States
Omics Approaches in Sleep-Wake Regulation
The Role of Glia in Sleep Regulation and Function
Sleep- and Wake-Like States in Small Networks In Vivo and In Vitro
Optogenetic Dissection of Sleep-Wake States In Vitro and In Vivo
Pharmacosynthetic Deconstruction of Sleep-Wake Circuits in the Brain
Clinical and Experimental Human Sleep-Wake Pharmacogenetics
Clinical Sleep-Wake Disorders I: Focus on Hypersomnias and Movement Disorders During Sleep
Clinical Sleep–Wake Disorders II: Focus on Insomnia and Circadian Rhythm Sleep Disorders
GABA Receptors and the Pharmacology of Sleep
Advances of Melatonin-Based Therapies in the Treatment of Disturbed Sleep and Mood
Dopamine and Wakefulness: Pharmacology, Genetics, and Circuitry
Ketamine-Induced Glutamatergic Mechanisms of Sleep and Wakefulness: Insights for Developing Novel Treatments for Disturbed Sleep and Mood
Adenosine and Sleep
Metabolite Clearance During Wakefulness and Sleep
Functional Interactions Between Sleep and Circadian Rhythms in Learning and Learning Disabilities
Sleep Physiology, Circadian Rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics

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