Review of Medical Microbiology and Immunology 14th edition by Warren Levinson ISBN 0071845747 978-0071845748

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ISBN 10: 0071845747
ISBN 13: 978-0071845748
Author:Warren Levinson

The most concise, clinically relevant, and current review of medical microbiology and immunology

Essential for USMLE review and medical microbiology coursework!

Review of Medical Microbiology and Immunology is a succinct, high-yield review of the medically important aspects of microbiology and immunology. It covers both the basic and clinical aspects of bacteriology, virology, mycology, parasitology, and immunology and also discusses important infectious diseases using an organ system approach. The book emphasizes the real-world clinical application of microbiology and immunology to infectious diseases and offers a unique mix of narrative text, color images, tables and figures, Q&A, and clinical vignettes.

Review of Medical Microbiology and Immunology 14th Table of contents:

Section 1: General Principles of Microbiology

1. Basic Principles of Microbiology

   • Overview of microbiology and its importance in medicine
   • Structure and function of microorganisms
   • Microscopy and staining techniques
   • Sterilization, disinfection, and antimicrobial agents

2. Microbial Genetics

   • Genetic mechanisms in bacteria (e.g., mutation, recombination)
   • Horizontal gene transfer (e.g., conjugation, transformation, transduction)
   • Antibiotic resistance and its genetic basis
   • Viruses and their genetic properties

3. Microbial Growth and Metabolism

   • Growth phases and conditions required for microbial growth
   • Metabolic pathways in bacteria and fungi
   • Pathogenesis and microbial survival strategies

Section 2: Bacteriology

4. General Bacteriology

   • Classification and identification of bacteria
   • Bacterial structure and function (cell wall, flagella, capsules, etc.)
   • Bacterial toxins, virulence factors, and pathogenesis

5. Aerobic Gram-Positive Cocci

   • Staphylococcus species (e.g., Staphylococcus aureus, coagulase-negative staphylococci)
   • Streptococcus species (e.g., Streptococcus pyogenes, Streptococcus pneumoniae)
   • Enterococcus species and their clinical significance

6. Aerobic Gram-Negative Bacilli

   • Escherichia coli and other Enterobacteriaceae
   • Pseudomonas aeruginosa and related pathogens
   • Haemophilus, Bordetella, and Legionella species

7. Anaerobic Bacteria

   • Clostridium species (e.g., C. botulinum, C. difficile)
   • Other anaerobes (e.g., Bacteroides, Fusobacterium)
   • Clinical implications of anaerobic infections

8. Spirochetes and Other Special Bacteria

   • Treponema, Borrelia, and Leptospira species
   • Mycobacterium tuberculosis and non-tuberculous mycobacteria
   • Rickettsiae, Chlamydia, and Mycoplasma

Section 3: Virology

9. General Principles of Virology

   • Virus structure and classification
   • Virus replication and life cycle
   • Host-virus interactions and pathogenesis

10. DNA Viruses

    • Herpesviruses (e.g., herpes simplex, varicella-zoster)
    • Adenoviruses and papillomaviruses
    • Hepatitis B virus (HBV)

11. RNA Viruses

    • Orthomyxoviruses (influenza)
    • Retroviruses (HIV, HTLV)
    • Picornaviruses (e.g., poliovirus, enteroviruses)
    • Coronaviruses and other RNA viruses

12. Emerging Viral Diseases

    • Zika virus, Ebola, and other emerging infections
    • New viral pathogens and their global impact

Section 4: Mycology (Fungi)

13. Fungal Biology

    • General characteristics of fungi
    • Fungal reproduction and growth
    • Yeasts, molds, and dimorphic fungi

14. Human Fungal Infections

    • Superficial and cutaneous fungal infections (e.g., dermatophytes, Candida)
    • Systemic fungal infections (e.g., Aspergillus, Histoplasma, Coccidioides)
    • Fungal infections in immunocompromised hosts

Section 5: Parasitology

15. Protozoa

    • Malaria (Plasmodium species)
    • Intestinal protozoa (e.g., Entamoeba histolytica, Giardia lamblia)
    • Other protozoan infections (e.g., Toxoplasma, Leishmania)

16. Helminths (Worms)

    • Nematodes (e.g., roundworms, pinworms)
    • Trematodes (e.g., schistosomiasis)
    • Cestodes (e.g., tapeworms)

17. Ectoparasites

    • Lice, fleas, and mites
    • Clinical manifestations of ectoparasitic infestations

Section 6: Immunology

18. Basic Immunology

    • The immune system: innate and adaptive immunity
    • Cells of the immune system (e.g., T-cells, B-cells, macrophages)
    • Antigen presentation and immune response

19. Humoral Immunity

    • Antibodies and their functions
    • B-cell activation and antibody production
    • Immunoglobulin classes and their clinical significance

20. Cell-Mediated Immunity

    • T-cell activation and function
    • Cytotoxic T-cells and helper T-cells
    • The role of cytokines in immune responses

21. Immunologic Disorders

    • Immunodeficiencies (e.g., HIV/AIDS, primary immunodeficiencies)
    • Hypersensitivity reactions (types I-IV)
    • Autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis)

22. Vaccines and Immunization

    • Principles of vaccination
    • Types of vaccines (e.g., live attenuated, inactivated, subunit vaccines)
    • Immunization schedules and strategies

Section 7: Clinical Microbiology and Infectious Diseases

23. Infectious Disease Diagnosis

    • Clinical signs and symptoms of infections
    • Laboratory diagnosis (e.g., cultures, PCR, serology)
    • Antimicrobial susceptibility testing

24. Antimicrobial Therapy

    • Mechanisms of action of antibiotics, antifungals, antivirals, and antiparasitics
    • Principles of antimicrobial stewardship
    • Resistance mechanisms and emerging resistant pathogens

25. Infectious Diseases by System

    • Respiratory infections (e.g., pneumonia, tuberculosis)
    • Gastrointestinal infections (e.g., foodborne illnesses, viral gastroenteritis)
    • Urinary tract infections and sexually transmitted diseases
    • Skin and soft tissue infections (e.g., cellulitis, abscesses)
    • Central nervous system infections (e.g., meningitis, encephalitis)

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