Rare tumors of the thyroid gland diagnosis and WHO classification 1st edition by José Manuel Cameselle Teijeiro, Catarina Eloy, Manuel Sobrinho Simões 9783319611822 3319611828

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ISBN 10: 3319611828
ISBN 13: 9783319611822 
Author: Cameselle-Teijeiro, José Manuel Eloy, Catarina Sobrinho-Simões, Manuel

This book documents the most important clinicopathological features of rare thyroid tumours with an emphasis (and ample documentation) on their histological and immunohistochemical aspects. Whenever necessary, namely for differential diagnosis and/or therapy purposes, molecular data are also highlighted. In order to understand the histogenesis of rare lesions and to be able to make a differential diagnosis, the editors use the WHO book for endocrine tumours (in preparation) as a framework for classifying thyroid tumours. In addition to characterizing the main histotypes of thyroid tumours, this book also provides detailed information on how to approach the diagnosis of tumours according to the major morphological/immunohistochemical characteristics, the predominant morphology and whether or not they are hereditary. This book is a valuable learning tool for those involved in the differential diagnosis of thyroid lesions. 

Rare tumors of the thyroid gland diagnosis and WHO classification 1st Table of contents:

1: Introduction
References

2: Rare Papillary Thyroid Carcinomas
Introduction
Hobnail (Micropapillary) Variant of Papillary Thyroid Carcinoma
Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma
Spindle Cell Variant of Papillary Thyroid Carcinoma
Spindle Cell Papillary Carcinoma with Fasciitis-Like Stroma/Fibromatosis
Angiomatoid Variant of Papillary Thyroid Carcinoma
Thyroglobulin-Negative Papillary Thyroid Carcinoma
Papillary Thyroid Carcinomas with Unusual Immunohistochemical Reactivity
Mucoepidermoid Carcinoma (MEC) of the Thyroid
Sclerosing Mucoepidermoid Carcinoma with Eosinophilia (SMECE)
Tumour-in-Tumour of the Thyroid with Neoplastic Solid Cell Nest Features
Tumour-in-Tumour Phenomenon Due to Metastatic Disease
Mixed Medullary-Papillary Carcinoma
References

3: Rare Follicular Tumours
Introduction
Oncocytic (Hürthle Cell, Oxyphilic) Tumours and Oncocytic Tumours with Clear Cells
Oncocytic (Hürthle Cell, Oxyphilic) Carcinoma Negative for TTF-1 and Thyroglobulin
Oncocytic (Hürthle Cell) Tumour with Non-specific Immunoreactivity
Lipid-Rich Follicular Tumours
Follicular Tumours with Signet Ring Cells
Atypical Adenoma (Including Spindle Cell Adenoma)
Meningioma-Like Follicular Adenoma
Pericytic-Like Follicular Adenoma
Hyalinizing Trabecular Neoplasms
Follicular Tumours with Glomeruloid Pattern of Growth
Mucinous Carcinoma
Hyperfunctioning (Hot) Follicular Thyroid Carcinoma
References

4: Small Cell Tumours
Introduction
Poorly Differentiated Carcinoma
Small Cell Variant of Medullary Thyroid Carcinoma
Calcitonin-Negative (Atypical) Medullary Thyroid Carcinoma
Thyroid Lymphoma
Metastatic Small Cell Carcinoma
Carcinoma of the Thyroid with Ewing Family Tumour Elements (CEFTE)
References

5: Rare Familial Tumours
Introduction
Cribriform-Morular Variant of Papillary Thyroid Carcinoma
PTEN Hamartoma Tumour Syndrome (PHTS)
DICER1 Syndrome
References

6: Other Rare Tumours and Tumour-­Like Lesions
Introduction
Solid Cell Nests (SCNs) and Related Lesions
Spindle Epithelial Tumour with Thymus-Like Differentiation (SETTLE)
Carcinoma Showing Thymus-Like Differentiation (CASTLE)
Solitary Fibrous Tumour
Florid Papillary Endothelial Proliferation
Spindle Cell Haemangioma
Kaposi Sarcoma
Epithelioid Haemangioendothelioma
Angiosarcoma
Diffuse Lipomatosis
References

7: Therapeutic Options
Introduction
Hobnail Variant of Papillary Thyroid Carcinoma
Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma
Oncocytic (Hürthle Cell) Carcinoma
Cribriform-Morular Variant of Papillary Thyroid Carcinoma
PTC with TERT Promoter Mutations (with or Without BRAF Mutations)
Poorly Differentiated Thyroid Carcinomas
References

Index

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