Practical Manual of Fetal Pathology 1st edition by Jelena Martinovic ISBN 303042491X 978-3030424916

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ISBN 10: 303042491X 
ISBN 13:  978-3030424916
Author: Jelena Martinovic 

This book provides a concise guide to fetal pathology and postnatal fetal examination. The legal and ethical aspects of fetal examination are addressed, along with the modern practical approach to fetal malformations, oriented fetal autopsy, neuro-fetopathological examination, and pathology of the placenta.

Practical Manual of Fetal Pathology aims to evaluate recent advancements and the impact they have had on clinical practice. This book is relevant to fetal and perinatal pathologists, geneticists, obstetricians, gynecologists, and pediatricians.

Practical Manual of Fetal Pathology 1st Table of contents:

• Introduction to Fetal Pathology

  • Overview of fetal pathology as a field of study.
  • Importance of fetal autopsy and its role in understanding congenital abnormalities, genetic disorders, and causes of fetal demise.
  • Techniques and methodology used in fetal autopsy and examination.

• Normal Fetal Development

  • Stages of fetal development and the major milestones.
  • Normal embryogenesis and organogenesis.
  • Fetal growth parameters and assessment techniques.

• Fetal Growth and Intrauterine Development

  • Factors influencing fetal growth, such as maternal health, nutrition, and placental function.
  • Intrauterine growth restriction (IUGR) and macrosomia.
  • Pathological causes of abnormal fetal growth.

• Congenital Anomalies of the Nervous System

  • Neural tube defects (e.g., anencephaly, spina bifida).
  • Brain malformations such as hydrocephalus, holoprosencephaly, and agenesis of the corpus callosum.
  • Infections and genetic causes of central nervous system malformations.

• Cardiovascular System Abnormalities

  • Congenital heart defects, including septal defects, tetralogy of Fallot, and transposition of the great arteries.
  • Pathology of the fetal heart and circulatory system.
  • Fetal arrhythmias and cardiac conduction disorders.

• Pulmonary Pathology

  • Developmental disorders of the lungs such as congenital diaphragmatic hernia.
  • Lung malformations, including pulmonary hypoplasia and cystic lung diseases.
  • Pathology of the respiratory system in cases of fetal demise.

• Renal and Urinary Tract Abnormalities

  • Congenital kidney malformations such as polycystic kidney disease and renal agenesis.
  • Obstructive uropathy and other developmental defects of the urinary tract.
  • Infections and other pathology of the fetal kidneys.

• Gastrointestinal System Disorders

  • Abnormalities of the gastrointestinal tract, including esophageal atresia, duodenal atresia, and intestinal malrotation.
  • Liver and biliary tract malformations.
  • Fetal abdominal wall defects such as gastroschisis and omphalocele.

• Musculoskeletal System Pathology

  • Congenital skeletal abnormalities like osteogenesis imperfecta, congenital scoliosis, and clubfoot.
  • Disorders of the limbs, including dysplasia and amniotic band syndrome.
  • Muscle and connective tissue disorders in the fetus.

• Endocrine System Disorders

  • Congenital adrenal hyperplasia and other endocrine malformations.
  • Thyroid disorders affecting fetal development.

• Genetic Disorders and Syndromes

  • Chromosomal abnormalities such as Down syndrome, Edwards syndrome, and Patau syndrome.
  • Single-gene disorders and inherited metabolic diseases.
  • Genetic testing and diagnostic techniques for fetal pathology.

• Placental Pathology

  • Abnormalities of placental development and structure.
  • Placental insufficiency and its effect on fetal health.
  • Infection and inflammation of the placenta.

• Infections in Pregnancy

  • Infections that affect the fetus, including TORCH infections (toxoplasmosis, rubella, cytomegalovirus, and herpes).
  • Pathology and outcomes of fetal infections.
  • Management and prevention of fetal infection.

• Fetal Demise

  • Causes of fetal death and stillbirth.
  • Pathologic investigation of stillbirth and the importance of autopsy.
  • Placental and fetal autopsy findings associated with fetal demise.

• Postmortem Examination and Diagnostic Techniques

  • Techniques used in fetal postmortem examination, including histopathology, molecular pathology, and imaging.
  • Role of advanced diagnostic tools like MRI in fetal pathology.
  • Case studies and examples of fetal autopsy findings.

• Ethical and Legal Considerations

  • Ethical issues in fetal autopsy, genetic counseling, and prenatal diagnosis.
  • Legal implications of fetal pathology findings in cases of stillbirth or suspected abuse.

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