Pathology of Pigmented Skin Lesions 1st edition by Jose Plaza, Victor Prieto ISBN ‎3662527197 978-3662527191

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ISBN 10: ‎ 3662527197 
ISBN 13:   978-3662527191
Author: Jose Plaza, Victor Prieto

This book offers a practical approach to the histologic analysis of a wide range of melanocytic skin lesions, including various nevi and different forms of melanoma, as well as pigmented non-melanocytic lesions. In addition, sentinel node biopsy findings and the use of special ancillary studies are covered in detail. Each chapter presents illustrative cases that document the route to correct diagnosis. An important feature of the book is the clinical-pathologic correlation of challenging melanocytic tumors; accordingly, it will appeal not only to pathologists (general surgical pathologists and dermatopathologists) but also to dermatologists (including dermatopathologists). The book contains some 250 color photos as well as tables and algorithms designed to assist in the diagnosis of difficult cases.​

Pathology of Pigmented Skin Lesions 1st  Table of contents:

• Introduction

  • Overview of Pigmented Skin Lesions
  • Classification and Terminology
  • Importance of Histopathological Diagnosis
  • Diagnostic Approach to Pigmented Lesions

• Chapter 1: Normal Skin Pigmentation

  • Melanin Production and Distribution
  • Function of Melanocytes and Epidermal Structure
  • Variations in Normal Skin Pigmentation

• Chapter 2: Benign Pigmented Lesions

  • Nevi (Moles)
    • Junctional Nevi
    • Compound Nevi
    • Intradermal Nevi
  • Lentigines
    • Solar Lentigo
    • Ephelides (Freckles)
  • Dermal Melanocytosis
    • Blue Nevi
    • Mongolian Spots
  • Becker’s Nevus and Other Variants

• Chapter 3: Dysplastic Nevi (Atypical Nevi)

  • Clinical and Histopathological Features
  • Risk Factors and Clinical Implications
  • Management and Follow-Up
  • Relationship to Melanoma

• Chapter 4: Malignant Melanoma

  • Types of Melanoma
    • Superficial Spreading Melanoma
    • Nodular Melanoma
    • Lentigo Maligna Melanoma
    • Acral Lentiginous Melanoma
    • Mucosal Melanoma
  • Histopathological Features of Melanoma
  • Staging and Prognostic Factors
  • Molecular Pathology and Genetic Mutations
  • Sentinel Lymph Node Biopsy

• Chapter 5: Pigmented Basal Cell Carcinoma

  • Clinical and Histopathological Characteristics
  • Subtypes of Basal Cell Carcinoma
  • Differential Diagnosis with Melanoma

• Chapter 6: Pigmented Squamous Cell Carcinoma

  • Clinical and Histopathological Presentation
  • Risk Factors for Pigmented SCC
  • Differentiating from Melanoma

• Chapter 7: Melanocytic Hyperplasia and Neoplasms

  • Pathogenesis and Molecular Mechanisms
  • Familial Syndromes with Increased Risk (e.g., Dysplastic Nevus Syndrome)
  • Molecular Pathology and Genetic Markers

• Chapter 8: Rare Pigmented Lesions

  • Pigmented Bowen’s Disease
  • Pigmented Dermatofibrosarcoma Protuberans
  • Pigmented Merkel Cell Carcinoma
  • Melanoacanthoma

• Chapter 9: Diagnostic Techniques in Pigmented Skin Lesions

  • Histopathological Diagnosis
  • Immunohistochemistry in Melanocytic Lesions
  • Molecular and Genetic Testing
  • Dermoscopy and Other Non-invasive Techniques

• Chapter 10: Management and Treatment

  • Surgical Excision and Margins
  • Mohs Micrographic Surgery
  • Adjuvant Therapy in Melanoma
  • Immunotherapy and Targeted Therapy
  • Monitoring for Recurrence and Metastasis

• Chapter 11: Prognosis and Follow-Up

  • Risk Assessment for Recurrence and Metastasis
  • Long-Term Monitoring for Melanoma and Other Pigmented Lesions
  • Role of Skin Surveillance Programs

• Chapter 12: Advances in Pigmented Skin Lesions Pathology

  • New Insights in the Molecular Pathology of Melanoma
  • Advances in Diagnostic Imaging and Techniques
  • Emerging Therapies for Melanoma and Other Pigmented Skin Lesions

• Conclusion

  • Summary of Key Concepts
  • Future Directions in the Study of Pigmented Skin Lesions

• Appendices

  • Glossary of Terms
  • Index
  • Further Reading and Resources

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