Pathology and Genetics of Head and Neck Tumours 1st Edition by The International Agency for Research on Cancer ISBN 9283224175 9789283224174

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ISBN 10: 9283224175 
ISBN 13: 9789283224174
Author: The International Agency for Research on Cancer

Pathology and Genetics of Head and Neck Tumours is the latest volume in the new WHO series, on histological and genetic typing of human tumours. This authoritative, concise reference book, provides an international standard for pathologists and oncologists and will serve as an indispensable, guide for use in the design of studies monitoring response to therapy and clinical outcome., Diagnostic criteria, pathological features, and associated genetic alterations are described in a, strictly disease-oriented manner. Sections on all WHO-recognized neoplasms and their variants include new ICD-O codes, incidence, age and sex distribution, location, clinical signs and symptoms, pathology, genetics, and predictive factors.

The book, prepared by 130 authors from 28 countries, contains 890 color photographs, X-rays, computed tomography (CT), magnetic resonance (MR) images, charts, and more than 2900 references.

This volume covers tumours of the nasal cavity and paranasal sinuses, of the nasopharynx, of the hypophyranyx, larynx and trachea, of the oral cavity and oropharynx, of salivary glands, as well as odontogenetic tumours, tumours of the ear, the paraganglionic system, and inherited tumour syndromes. Each entity is extensively discussed with information on clinicopathological, epidemiological, immunophenotypic and genetic aspects of these diseases.

Pathology and Genetics of Head and Neck Tumours 1st Table of contents:

• General Considerations in the Classification of Head and Neck Tumours

  • Classification Systems for Head and Neck Cancer
  • Role of Histopathology and Molecular Genetics
  • Diagnostic Challenges

• Tumours of the Lip and Oral Cavity

  • Benign and Malignant Tumours of the Lip
  • Tumours of the Oral Mucosa, Tongue, and Salivary Glands
  • Squamous Cell Carcinoma and Other Lesions

• Tumours of the Oropharynx and Nasopharynx

  • Benign and Malignant Tumours of the Oropharynx
  • Nasopharyngeal Carcinoma: Pathology and Genetics
  • Lymphoepithelial Tumours

• Tumours of the Larynx and Hypopharynx

  • Laryngeal Squamous Cell Carcinoma
  • Rare Tumours of the Larynx and Hypopharynx

• Tumours of the Nasal Cavity and Paranasal Sinuses

  • Tumours of the Nasal Mucosa and Paranasal Sinuses
  • Sinonasal Squamous Cell Carcinoma
  • Other Sinonasal Malignancies

• Salivary Gland Tumours

  • Classification of Benign and Malignant Salivary Gland Tumours
  • Pathology of Major Salivary Glands (Parotid, Submandibular, Sublingual)
  • Molecular and Genetic Insights into Salivary Gland Tumours

• Tumours of the Thyroid Gland

  • Thyroid Carcinomas and Their Genetic Basis
  • Medullary Thyroid Carcinoma
  • Anaplastic Thyroid Carcinoma

• Soft Tissue Tumours of the Head and Neck

  • Benign and Malignant Soft Tissue Tumours
  • Fibromas, Lipomas, and Sarcomas

• Cranial Nerve and Paraganglionic Tumours

  • Tumours Involving the Cranial Nerves
  • Paragangliomas and Neuroendocrine Tumours

• Pathology and Genetics of Metastatic Tumours in the Head and Neck

  • Patterns of Metastasis to the Head and Neck
  • Molecular Mechanisms of Metastatic Spread

• Molecular Genetics and Tumour Pathogenesis

  • Genetic Alterations in Head and Neck Tumours
  • Molecular Pathways Involved in Carcinogenesis
  • Biomarkers for Diagnosis and Prognosis

• Clinical Implications and Management

  • Implications of Pathology and Genetics for Treatment
  • Surgical and Non-Surgical Treatment Approaches
  • Role of Genetic Profiling in Personalized Medicine

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