Natural products and human diseases 1st Edition by Amirhossein Sahebkar, Thozhukat Sathyapalan ISBN B09PMN6GRX 9783030732332

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Product details:
ISBN 10: B09PMN6GRX
ISBN 13: 9783030732332
Author: Amirhossein Sahebkar, Thozhukat Sathyapalan

Natural products have a long history of use as folk medicines in several systems of traditional medicine. Extensive evidence from modern pharmacological studies has confirmed traditional applications, and unveiled the vast potential of naturally occurring compounds, particularly plant-derived phytochemicals, in the management of chronic human diseases. The past decade has witnessed a surge of findings from randomized controlled trials testifying the safety and efficacy of natural products as adjuncts or alternatives to standard-of-care medications for several illnesses. Biomolecular studies have unveiled hundreds of cellular and molecular targets for phytochemicals including key transcription factors, receptors, enzymes, hormones, neurotransmitters, cytokines, lipids, and non-coding RNAs.

Extensive research on the preventative and therapeutic effects of natural products necessitates regular updating of the literature as to the developing potential roles of these compounds in different human diseases. This new book provides an overview of the current pharmacological and clinical features of natural products, and the role of phytopharmaceutical compounds in health and diseases. Chapters cover a wide scope, from cancers, to chronic and age-related disorders, and are written by leading international subject experts. Collectively, chapters will provide useful insights on the regulatory effects of phytochemicals and nutraceuticals on pathogenic molecular signatures associated with pathologies, disease biomarkers, and aging-related pathways.

Natural products and human diseases 1st Edition Table of contents:

Section 1: Introduction to Natural Products and Human Health

1. Overview of Natural Products: Historical and Modern Perspectives
2. Natural Products in Traditional Medicine
3. Mechanisms of Action of Bioactive Natural Compounds

Section 2: Natural Products and Chronic Diseases
4. Role of Natural Products in Cardiovascular Diseases
5. Natural Compounds in Diabetes Management
6. Anti-inflammatory Natural Products in Arthritis and Related Disorders
7. Natural Products for Obesity and Metabolic Syndrome

Section 3: Natural Products and Cancer
8. Anticancer Properties of Plant-Derived Compounds
9. Marine Natural Products in Cancer Therapy
10. Synergistic Effects of Natural Products with Chemotherapy

Section 4: Natural Products and Neurodegenerative Disorders
11. Neuroprotective Effects of Natural Compounds in Alzheimer’s Disease
12. Role of Natural Products in Parkinson’s and Other Neurological Disorders

Section 5: Natural Products in Infectious Diseases
13. Antibacterial and Antiviral Properties of Natural Compounds
14. Antifungal and Antiparasitic Natural Products
15. Natural Products in the Era of Antibiotic Resistance

Section 6: Emerging Applications of Natural Products
16. Natural Compounds for Immune Modulation
17. Natural Products in Skin Health and Dermatological Conditions
18. Role of Natural Products in Respiratory and Gastrointestinal Disorders

Section 7: Advances in Natural Product Research and Applications
19. Advances in Extraction and Isolation of Bioactive Natural Products
20. Role of Nanotechnology in Natural Product Delivery
21. Challenges and Opportunities in Clinical Translation of Natural Products

Section 8: Case Studies and Future Directions
22. Successful Case Studies in Natural Product-Based Drug Development
23. Ethical and Regulatory Aspects of Natural Product Research
24. Future Trends in Natural Product Applications for Human Health

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