Nanotechnology Enhanced Orthopedic Materials 1st Edition by Lei Yang ISBN 0857098446 9780857098443

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ISBN 10: 0857098446 
ISBN 13: 9780857098443
Author: Lei Yang

Nanotechnology-Enhanced Orthopedic Materials provides the latest information on the emergence and rapid development of nanotechnology and the ways it has impacted almost every aspect of biomedical engineering.

This book provides readers with a comprehensive overview of the field, focusing on the fabrication and applications of these materials, presenting updated, practical, and systematic knowledge on the synthesis, processing, and modification of nanomaterials, along with the rationale and methodology of applying such materials for orthopedic purposes.

Topics covered include a wide range of orthopedic material formulations, such as ceramics, metals, polymers, biomolecules, and self-assemblies. Final sections explore applications and future trends in nanotechnology-enhanced orthopedic materials.

• Details practical information on the fabrication and modification of new and traditional orthopedic materials
• Analyzes a wide range of materials, designs, and applications of nanotechnology for orthopedics
• Investigates future trends in the field, including sections on orthopedic materials with bacterial-inhibitory properties and novel materials for the control of immune and inflammatory responses

Nanotechnology Enhanced Orthopedic Materials 1st Table of contents:

Chapter 1: Introduction to Nanotechnology in Orthopedic Materials

• Overview of Nanotechnology and Its Applications in Medicine
• Role of Nanotechnology in Orthopedics
• Key Concepts in Nanomaterials: Size, Surface Area, and Properties
• Benefits of Nanotechnology for Orthopedic Devices
• Challenges in Translating Nanotechnology to Clinical Applications

Chapter 2: Fundamentals of Nanomaterials for Orthopedic Applications

• Types of Nanomaterials: Nanoparticles, Nanofibers, Nanotubes, and Nanocomposites
• Physical, Chemical, and Biological Properties of Nanomaterials
• Synthesis and Characterization of Nanomaterials
• Biocompatibility, Toxicity, and Safety Considerations
• Surface Functionalization and Modification for Orthopedic Use

Chapter 3: Nanotechnology in Bone and Joint Regeneration

• Role of Nanomaterials in Bone Healing and Regeneration
• Nanostructured Scaffolds for Bone Tissue Engineering
• Biodegradable Nanomaterials in Bone Regeneration
• Nanoparticles for Delivery of Growth Factors and Stem Cells
• Enhancing Osteointegration with Nanotechnology
• Clinical Applications in Bone Defects and Fracture Repair

Chapter 4: Nanocoatings for Orthopedic Implants

• Importance of Surface Coatings for Implants
• Nanocoatings for Improved Biocompatibility and Wear Resistance
• Functionalization of Nanocoatings for Anti-bacterial and Anti-inflammatory Effects
• Types of Nanocoatings: Hydroxyapatite, Titanium Oxide, and Polymeric Coatings
• Techniques for Nanocoating Implants: Chemical Vapor Deposition, Plasma Spraying, and Sol-Gel Processes
• Clinical Performance of Nanocoated Orthopedic Implants

Chapter 5: Nanotechnology in Orthopedic Biomaterials for Joint Replacement

• Nanocomposites for Hip, Knee, and Shoulder Implants
• Enhancing Wear Resistance and Longevity of Joint Replacements with Nanotechnology
• Nanostructured Polymer Composites for Joint Replacement Bearings
• Challenges and Innovations in Nanotechnology for Prosthetic Joints
• Clinical Outcomes of Nanotechnology-Based Joint Implants

Chapter 6: Nanoparticles in Drug Delivery for Orthopedic Applications

• Role of Nanoparticles in Controlled Drug Delivery
• Drug-Eluting Implants and Coatings for Bone Healing and Infection Prevention
• Nanoparticles for Targeted Delivery of Growth Factors and Antibacterial Agents
• Nanoparticles in Localized Treatment of Osteoarthritis and Inflammation
• Clinical Use of Nanoparticle-Based Drug Delivery Systems in Orthopedics

Chapter 7: Nano-Enabled Orthopedic Devices for Fracture Fixation and Repair

• Nanocomposite Materials for Bone Plates, Screws, and Pins
• Nanotechnology in Fracture Healing: Accelerating Recovery
• Biodegradable Nanomaterials for Temporary Fixation Devices
• Smart Implants with Nano-Sensors for Monitoring Bone Healing
• Clinical Applications of Nano-Enabled Fracture Fixation Devices

Chapter 8: Nanotechnology in Spine Surgery and Implants

• Nanomaterials for Spinal Implants: Improving Strength and Biocompatibility
• Nanocoatings for Spinal Fusion Devices
• Nanotechnology in Intervertebral Disc Regeneration
• Role of Nanoparticles in Treating Spinal Osteoarthritis and Degeneration
• Future Trends in Nanotechnology for Spine Surgery

Chapter 9: Nanotechnology for Soft Tissue Repair in Orthopedics

• Nanomaterials in Ligament and Tendon Regeneration
• Nano-Scaffolds for Soft Tissue Engineering
• Enhancing Soft Tissue Integration with Bone Implants
• Nanoparticles in Cartilage Repair and Regeneration
• Clinical Outcomes in Soft Tissue Repair Using Nanotechnology

Chapter 10: Biomechanics of Nanotechnology-Enhanced Orthopedic Implants

• Mechanical Properties of Nanomaterials in Orthopedic Applications
• Enhancing Implant Strength, Durability, and Fatigue Resistance
• Nanotechnology in the Prevention of Implant Loosening and Wear
• Modeling and Simulation of Nanotechnology-Based Orthopedic Devices
• Long-Term Performance and Durability of Nanotechnology-Enhanced Implants

Chapter 11: Regulatory and Ethical Considerations in Nanotechnology for Orthopedics

• Regulatory Guidelines for Nanomaterials in Medical Devices
• FDA and International Standards for Nanotechnology in Orthopedics
• Ethical Considerations in the Use of Nanotechnology in Implants
• Safety, Toxicity, and Risk Assessment of Nanomaterials
• Patient Education and Consent for Nanotechnology-Based Implants

Chapter 12: Future Directions and Challenges in Nanotechnology for Orthopedics

• Emerging Nanomaterials for Orthopedic Applications
• The Role of Nanotechnology in Personalized Orthopedic Treatments
• Challenges in Scaling Up Nanotechnology for Clinical Use
• The Impact of Nanotechnology on Minimally Invasive Orthopedic Surgery
• Collaborative Research and Innovation in Orthopedic Nanotechnology

Chapter 13: Case Studies and Clinical Applications

• Case Study 1: Nanotechnology in Total Hip and Knee Replacement
• Case Study 2: Bone Defect Regeneration Using Nanostructured Scaffolds
• Case Study 3: Nanotechnology-Based Spinal Fusion Implants
• Case Study 4: Application of Nanoparticle-Based Drug Delivery Systems in Orthopedic Surgery
• Case Study 5: Clinical Outcomes of Nanocoated Implants in Orthopedic Trauma

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