Middleton Allergy Essentials 1st Edition by Robyn E O Hehir, Stephen T Holgate, Aziz Sheikh ISBN 0323392741 9780323392747

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ISBN 10: 0323392741 
ISBN 13: 9780323392747
Author: Robyn E O Hehir, Stephen T Holgate, Aziz Sheikh

For decades, health care practitioners have relied on Middleton’s Allergy as their go-to reference for comprehensive information on allergic disorders. Now Middleton’s Allergy Essentials, by Drs. Robyn E. O’Hehir, Stephen T. Holgate, and Aziz Sheikh, offers a concise resource that’s both easily accessible and highly authoritative. Perfect for clinicians in primary and secondary care settings, this practical volume covers what is most useful in your daily practice, with a strong emphasis on disease diagnosis and management.

Middleton Allergy Essentials 1st Table of contents:

Chapter 1 Introduction to Mechanisms of Allergic Diseases
Introduction
Innate Immunity
Adaptive Immunity
Immunoglobulin Structure and Function
Immunoglobulins and Human Disease
Immune Tolerance
Cytokines and Chemokines in Allergic Inflammation
Biology of Immune Cells
Contribution of Structural Cells to Allergic Inflammations
Cytokine Networks in Allergic Inflammation
Resolution of Allergic Inflammation and Major Pathways
References
Chapter 2 The Origins of Allergic Disease
Introduction
Genetics of Allergic Disease
Current Understanding of Allergic Disease Genetics
Gene–Environment Interaction
Pharmacogenetics of Allergic Disease
Epigenetics and Allergic Disease
Potential for Clinical Application of Genetics in Allergic Disease
Developmental Origins of Allergic Disease
Conclusions
References
Chapter 3 Epidemiology of Allergic Diseases
Introduction
Definitions
Estimates of Worldwide Prevalence of Asthma, Rhinitis, Atopic Sensitization, and Food Allergy
Trends in Prevalence Over Time
Risk Factors for Asthma and Allergic Diseases
Concluding Remarks: Epidemiology in the 21st Century
References
Chapter 4 Indoor and Outdoor Allergens and Pollutants
Introduction
Allergens and Allergenicity
Indoor and Outdoor Allergen Sources
Aerobiology of Indoor and Outdoor Allergen Sources
Outdoor Allergen Monitoring
Indoor Allergen Monitoring
The Chemical Nature of Allergens
Allergen Nomenclature and Allergen Databases
Outdoor Allergens
Indoor Allergens
Allergens and Allergenicity
Environmental Modifiers of Allergic Sensitization and Disease
Air Pollution, Allergic Sensitization, and Disease
Types of Pollutant and Their Effects on Allergens, Allergic Sensitization, and Asthma
Conclusions
Acknowledgments
References
Chapter 5 Principles of Allergy Diagnosis
Introduction
Historical Perspectives
Epidemiology
Pathogenesis and Etiology
Clinical Features
The Allergen Extracts
The Technique
The Patient
Referral
Conclusions
References
Chapter 6 Allergen-specific Immunotherapy
Introduction
Historical Perspective
Indications for Specific Allergen Immunotherapy
Clinical Efficacy with Specific Allergens
Specificity of Allergen Immunotherapy
Evidence of Disease Modification
Pharmacoeconomics of SIT
Immunologic Response to Inhalant SIT
End-Organ Changes
Overview of the Immune Response to Immunotherapy
Indications for SIT
Sublingual Immunotherapy
Other Potential Modes of Administration
Modified Allergen Extracts and Adjuvants (Box 6-6)
The Future of SLIT
Conclusions
References
Chapter 7 Asthma
Introduction and Overview
Historical Perspective
Epidemiology
Pathogenesis and Etiology
Clinical Features and Phenotypes of Asthma
Evaluation and Diagnosis
Asthma Management
Acute Asthma and Referral for Hospital Care
Conclusions
References
Chapter 8 Allergic Rhinitis and Conjunctivitis
Introduction
Historic Perspective
Epidemiology
Pathogenesis and Etiology
Treatment
Indications for Referral
Conclusions
References
Chapter 9 Drug Allergy
Introduction
Historical Perspective
Epidemiology
Pathogenesis and Etiology
Clinical Features (Phenotypes)
Patient Evaluation, Diagnosis, and Differential Diagnosis
Drug Classes of Special Interest
Treatment
Conclusions
References
Chapter 10 Urticaria and Angioedema without Wheals
Introduction and Historical Perspective
Definitions and Classifications
Epidemiology
Natural History and Prognosis
Disease Associations
Pathogenesis and Etiology
Diagnostic Approach
Treatment of Urticaria
References
Chapter 11 Atopic Dermatitis and Allergic Contact Dermatitis
Introduction
Historical Perspective
Epidemiology
Pathogenesis and Etiology
Clinical Features (Phenotype)
Patient Evaluation, Diagnosis, and Differential Diagnosis
Treatment
Conclusions
References
Chapter 12 Food Allergy and Gastrointestinal Syndromes
Introduction
Historical Perspective
Epidemiology
Clinical Features
Patient Evaluation, Diagnosis, and Differential Diagnosis
Food Allergy Treatment
Emergency Management
Future Therapeutic Strategies
Conclusions
References
Chapter 13 Anaphylaxis
Introduction
Historical Perspective
Epidemiology
Pathophysiology
Clinical Features (Phenotypes)
Patient Evaluation, Diagnosis, and Differential Diagnosis
Treatment
Ongoing Management and Referral
Conclusions
References
Chapter 14 Occupational Allergy
Introduction and Definitions
Historical Perspectives
Epidemiology
Pathogenesis and Etiology
Clinical Features
Patient Evaluation, Diagnosis, and Differential Diagnosis
Outcomes and Treatment
Prevention
Socioeconomic Impact and Medicolegal Aspects
Work-Related Anaphylaxis
Conclusions
References
Chapter 15 Insect Allergy
Stinging Insect Allergy
Historical Perspective
Epidemiology
Etiology
Insect Venoms
Clinical Features and Classification of Reactions
Patient Evaluation and Diagnosis
Treatment of Acute Reactions
Prevention of Acute Reactions
Predictors of Risk for Sting Anaphylaxis
Venom Immunotherapy
Biting Insect Allergy

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