Microbial Biotechnology Fundamentals of Applied Microbiology 2nd edition by Alexander N Glazer, Hiroshi Nikaido ISBN 0521842107 978-0521842105

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ISBN 10:  0521842107
ISBN 13: 978-0521842105
Author: Alexander N Glazer, Hiroshi Nikaido

Knowledge in microbiology is growing exponentially through the determination of genomic sequences of hundreds of microorganisms and the invention of new technologies such as genomics, transcriptomics, and proteomics, to deal with this avalanche of information.

These genomic data are now exploited in thousands of applications, ranging from those in medicine, agriculture, organic chemistry, public health, biomass conversion, to biomining. Microbial Biotechnology. Fundamentals of Applied Microbiology focuses on uses of major societal importance, enabling an in-depth analysis of these critically important applications. Some, such as wastewater treatment, have changed only modestly over time, others, such as directed molecular evolution, or ‘green’ chemistry, are as current as today’s headlines.

This fully revised second edition provides an exciting interdisciplinary journey through the rapidly changing landscape of discovery in microbial biotechnology. An ideal text for courses in applied microbiology and biotechnology courses, this book will also serve as an invaluable overview of recent advances in this field for professional life scientists and for the diverse community of other professionals with interests in biotechnology.

Microbial Biotechnology: Fundamentals of Applied Microbiology 2nd Table of contents:

Chapter 1: Introduction to Microbial Biotechnology

• Definition and Scope of Microbial Biotechnology

• Historical Development of Microbial Biotechnology

• Applications of Microbial Biotechnology in Industry, Medicine, and Environmental Science

• The Role of Microbes in Biotechnology

• Future Trends and Emerging Fields in Microbial Biotechnology

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Chapter 2: Microbial Diversity and Classification

• Overview of Microbial Diversity

• Classification of Microorganisms: Bacteria, Fungi, Viruses, and Algae

• Major Microbial Groups in Biotechnology

• Microbial Taxonomy and Phylogeny

• Techniques for Identifying and Classifying Microorganisms

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Chapter 3: Microbial Metabolism and Physiology

• Overview of Microbial Metabolism

• Aerobic and Anaerobic Respiration in Microorganisms

• Microbial Growth and Reproduction

• Nutrient Requirements and Uptake Mechanisms

• Biochemical Pathways in Microbial Cells: Glycolysis, TCA Cycle, and Fermentation

• Regulation of Metabolic Pathways

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Chapter 4: Genetic Engineering in Microbial Biotechnology

• Introduction to Genetic Engineering and Recombinant DNA Technology

• Techniques in Genetic Modification of Microorganisms

• Cloning Vectors and Gene Insertion Methods

• Gene Expression and Regulation in Microbial Systems

• Applications of Genetic Engineering in Microbial Biotechnology

• Ethical Considerations and Safety in Genetic Engineering

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Chapter 5: Industrial Microbiology and Bioprocessing

• Principles of Industrial Microbiology

• The Role of Microorganisms in Bioprocesses

• Types of Bioreactors and Their Applications

• Fermentation Technology: Batch and Continuous Processes

• Scaling Up: Challenges and Considerations in Industrial Microbiology

• Industrial Microbial Products: Enzymes, Antibiotics, and Biofuels

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Chapter 6: Enzyme Biotechnology

• Introduction to Enzyme Biotechnology

• Types of Enzymes Used in Biotechnology: Hydrolases, Oxidoreductases, and Ligases

• Enzyme Production, Purification, and Characterization

• Industrial Applications of Enzymes: Food, Pharmaceuticals, and Biofuels

• Enzyme Immobilization and Its Industrial Significance

• Future Trends in Enzyme Biotechnology

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Chapter 7: Microbial Fermentation and Its Applications

• Principles of Fermentation Technology

• Types of Fermentation: Solid-State, Submerged, and Semi-Solid Fermentation

• Industrial Fermentation for the Production of Pharmaceuticals, Biofuels, and Food Additives

• Optimization of Fermentation Conditions

• Microbial Metabolites and Secondary Metabolite Production

• Bioreactor Design and Operation in Fermentation

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Chapter 8: Microbial Production of Pharmaceuticals and Bioactive Compounds

• Microbial Production of Antibiotics: Mechanisms and Applications

• The Role of Microorganisms in Producing Vaccines and Therapeutic Proteins

• Biotechnological Production of Vitamins, Amino Acids, and Other Nutraceuticals

• Production of Biologically Active Molecules from Microbes

• Case Studies: Antibiotics (Penicillin, Streptomycin) and Other Pharmaceutical Products

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Chapter 9: Environmental Microbial Biotechnology

• The Role of Microorganisms in Environmental Biotechnology

• Microbial Bioremediation: Cleanup of Pollutants and Toxic Compounds

• Wastewater Treatment and the Role of Microbes in Degradation

• Environmental Monitoring and Microbial Indicators of Pollution

• Microbial Bioenergy: Biofuels, Biogas, and Hydrogen Production

• Biocatalysis and Environmental Sustainability

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Chapter 10: Agricultural Microbial Biotechnology

• The Role of Microorganisms in Agriculture

• Microbial Fertilizers and Biopesticides

• Plant Growth-Promoting Rhizobacteria (PGPR)

• Microbial Control of Plant Diseases

• Mycorrhizal Fungi and Their Role in Soil Health

• Microbes in Biotransformation of Agricultural Waste

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Chapter 11: Microbial Biotechnology in Food Industry

• Applications of Microorganisms in Food Production

• Fermented Foods: Dairy, Beverages, and Vegetables

• Microbial Inoculants in Food Processing

• Microbial Enzymes in the Food Industry

• Food Safety: Detection and Control of Pathogens

• Probiotics and Functional Foods

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Chapter 12: Bioprocessing, Bioreactors, and Scale-Up in Microbial Biotechnology

• Bioprocessing and its Role in Biotechnology

• Bioreactor Design and Types: Stirred-Tank, Airlift, and Fixed-Bed

• Monitoring and Control in Bioreactor Operations

• Scaling Up Microbial Cultures: Challenges and Considerations

• Industrial Case Studies in Bioprocessing

• Economic and Environmental Considerations in Bioprocess Design

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Chapter 13: Safety, Regulation, and Ethical Issues in Microbial Biotechnology

• Biosafety in Microbial Biotechnology Laboratories

• Genetic Modification and Its Regulatory Framework

• Environmental Impact of Biotechnology Applications

• Ethical Issues in Genetic Engineering and GMOs

• Global Regulatory Standards and Compliance for Biotech Products

• Public Perception and Biotechnology: Challenges in Communication

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Chapter 14: Future Directions in Microbial Biotechnology

• Emerging Technologies in Microbial Biotechnology

• Synthetic Biology and Its Potential Applications

• Personalized Medicine and Microbial Biotechnology

• The Role of Microbial Biotechnology in Addressing Global Challenges: Food Security, Disease, and Climate Change

• Bioinformatics and Systems Biology in Microbial Biotechnology

• The Future of Microbial Biotechnology: Opportunities and Challenges

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Appendices

• A. Glossary of Key Terms in Microbial Biotechnology

• B. Microbial Culture Media and Techniques

• C. Protocols for Common Microbiological Experiments

• D. Further Reading and Resources

Index

• Subject Index

• Author Index

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