Microbial Biotechnology Fundamentals of Applied Microbiology 2nd Edition by Alexander Glazer, Hiroshi Nikaido ISBN 9781316099360 1316099369
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Authors:Alexander N. Glazer; Hiroshi Nikaido , Series:Microbiology [15] , Tags:Science; Life Sciences; Microbiology; Biotechnology; Molecular Biology; Genetics & Genomics , Author sort:Glazer, Alexander N. & Nikaido, Hiroshi , Ids:9781139465632 , Languages:Languages:eng , Published:Published:Oct 2007 , Publisher:CAMBRIDGE UNIVERSITY PRESS , Comments:Comments:Knowledge in microbiology is growing exponentially through the determination of genomic sequences of hundreds of microorganisms and the invention of new technologies such as genomics, transcriptomics, and proteomics, to deal with this avalanche of information. These genomic data are now exploited in thousands of applications, ranging from those in medicine, agriculture, organic chemistry, public health, biomass conversion, to biomining. Microbial Biotechnology. Fundamentals of Applied Microbiology focuses on uses of major societal importance, enabling an in-depth analysis of these critically important applications. Some, such as wastewater treatment, have changed only modestly over time, others, such as directed molecular evolution, or ‘green’ chemistry, are as current as today’s headlines. This fully revised second edition provides an exciting interdisciplinary journey through the rapidly changing landscape of discovery in microbial biotechnology. An ideal text for courses in applied microbiology and biotechnology courses, this book will also serve as an invaluable overview of recent advances in this field for professional life scientists and for the diverse community of other professionals with interests in biotechnology.
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ISBN 10: 1316099369
ISBN 13: 9781316099360
Author: Alexander Glazer, Hiroshi Nikaido
Microbial Biotechnology Fundamentals of Applied Microbiology 2nd Edition Table of contents:
1 Microbial Diversity
Prokaryotes and Eukaryotes
The Importance of the Identification and Classification of Microorganisms
Plasmids and the Classification of Bacteria
Analysis of Microbial Populations in Natural Environments
Taxonomic Diversity of Bacteria with Uses in Biotechnology
Characteristics of the Fungi
Classification of the Fungi
Culture Collections and the Preservation of Microorganisms
Summary
Selected References and Online Resources
2 Microbial Biotechnology: Scope, Techniques, Examples
Human Therapeutics
Agriculture
Food Technology
Single-Cell Protein
Environmental Applications of Microorganisms
Microbial Whole-Cell Bioreporters
Organic Chemistry
Summary
Selected References and Online Resources
3 Production of Proteins in Bacteria and Yeast
Production of Proteins in Bacteria
Production of Proteins in Yeast
Summary
Selected References
4 The World of “Omics”: Genomics, Transcriptomics, Proteomics, and Metabolomics
Genomics
Transcriptomics
Proteomics
Metabolomics and Systems Biology
Summary
Selected References
5 Recombinant and Synthetic Vaccines
Problems with Traditional Vaccines
Impact of Biotechnology on Vaccine Development
Mechanisms for Producing Immunity
Improving the Effectiveness of Subunit Vaccines
Fragments of Antigen Subunit Used as Synthetic Peptide Vaccines
DNA Vaccines
Vaccines in Development
Summary
Selected References
6 Plant–Microbe Interactions
Use of Symbionts
Production of Transgenic Plants
Summary
Selected References
7 Bacillus thuringiensis (Bt) Toxins: Microbial Insecticides
Bacillus thuringiensis
Insect-Resistant Transgenic Crops
Benefit and Risk Assessment of Bt Crops
Summary
Selected References and On-Line Resources
8 Microbial Polysaccharides and Polyesters
Polysaccharides
Xanthan Gum
Polyesters
Summary
References
9 Primary Metabolites: Organic Acids and Amino Acids
Citric Acid
Amino Acid: l-Glutamate
Amino Acids Other Than Glutamate
Amino Acid Production with Enzymes
Summary
Selected References
10 Secondary Metabolites: Antibiotics and More
Activities of Secondary Metabolites
Primary Goals of Antibiotic Research
Development of Aminoglycosides
Development of the β-Lactams
Production of Antibiotics
Problem of Antibiotic Resistance
Summary
Selected References
11 Biocatalysis in Organic Chemistry
Microbial Transformation of Steroids and Sterols
Asymmetric Catalysis in the Pharmaceutical and Agrochemical Industries
Microbial Diversity: A Vast Reservoir of Distinctive Enzymes
High-Throughput Screening of Environmental DNA for Natural Enzyme Variants with Desired Catalytic Properties: An Example
Approaches to Optimization of the “Best Available” Natural Enzyme Variants
Rational Methods of Protein Engineering
Large-Scale Biocatalytic Processes
Summary
References
12 Biomass
Major Components of Plant Biomass
Degradation of Lignocellulose by Fungi and Bacteria
Degradation of Lignin
Degradation of Cellulose
Degradation of Hemicelluloses
The Promise of Enzymatic Lignocellulose Biodegradation
Summary
References and Online Resources
13 Ethanol
Stage I: From Feedstocks to Fermentable Sugars
Stage II: From Sugars to Alcohol
Simultaneous Saccharification and Fermentation: Stages I and II Combined
Prospects of Fuel Ethanol from Biomass
Summary
References and Online Resources
14 Environmental Applications
Degradative Capabilities of Microorganisms and Origins of Organic Compounds
Wastewater Treatment
Microbiological Degradation of Xenobiotics
Microorganisms in Mineral Recovery
Microorganisms in the Removal of Heavy Metals from Aqueous Effluent
Summary
References
Index
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