Lung Cancer Molecular Pathology Methods and Reviews Volume 1 1st edition by Barbara Driscoll – Ebook PDF Instant Download/Delivery.0896039854, 9780896039858
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ISBN 10: 0896039854
ISBN 13: 9780896039858
Author: Barbara Driscoll
The Methods in Molecular Medicine series is intended as a resource for both novice and experienced investigators attempting to diversify their tech- logical base in research. Lung Cancer: Volume 1: Molecular Pathology Me- ods and Reviews presents an overview of the current status of assays employed to detect and characterize the multitude of pathologies that contribute to the development of this deadly disease. As with all volumes in the Methods in Molecular Medicine series, the reader should find that each methods-based chapter provides clear instructions for the performance of various protocols, supplemented by additional technical notes that provide valuable insight. These notes are designed to enable the reader to acquire the techniques described with a proficiency not easily achieved by re- ing standard method formats. No volume can exhaustively cover every aspect of biological research and there will be gaps in this endeavor that one or another research group will id- tify. Each section herein could readily be expanded into a book in its own right. However, I have sought to include a spectrum of techniques that should allow for the acquisition of key skills in each area covered.
Lung Cancer Molecular Pathology Methods and Reviews Volume 1 1st Table of contents:
Lung Cancer Molecular Pathology Methods and Reviews Volume 1 table of contents :
Introduction
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Characteristic Genetic Alterations in Lung Cancer – Ignacio I. Wistuba, Adi F. Gazdar (Pages 3-28)
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Etiology and Classification of Lung Tumors
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Clinical and Biological Relevance of Recently Defined Categories of Pulmonary Neoplasia – Edward Gabrielson (Pages 31-42)
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Molecular Epidemiology of Human Cancer Risk – Kirsi Vähäkangas (Pages 43-59)
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Neuroendocrine Phenotype of Small Cell Lung Cancer – Judy M. Coulson, Marta Ocejo-Garcia, Penella J. Woll (Pages 61-73)
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AIDS-Associated Pulmonary Cancers – Kushagra Katariya, Richard J. Thurer (Pages 75-86)
Molecular Abnormalities in Lung Cancer
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Abrogation of the RB-p16 Tumor Suppressor Pathway in Human Lung Cancer – Joseph Geradts (Pages 89-99)
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Sensitive Detection of Hypermethylated p16INK4a Alleles in Exfoliative Tissue Material – Marcus Schuermann, Michael Kersting (Pages 101-109)
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Role of Receptor Tyrosine Kinases in Lung Cancer – Gautam Maulik, Takashi Kijima, Ravi Salgia (Pages 113-125)
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Relationship of EGFR Signal-Transduction Modulation by Tyrosine Kinase Inhibitors to Chemosensitivity and Programmed Cell Death in Lung Cancer Cell Lines – Wendong Lei, Patrick P. Koty, Mark L. Levitt (Pages 127-143)
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Detection of the Transcripts and Proteins for the Transforming Growth Factor-β Isoforms and Receptors in Mouse Lung Tumorigenesis Using In Situ Hybridization and Immunohistochemistry in Paraffin-Embedded Tissue Sections – Sonia B. Jakowlew, Jennifer Mariano (Pages 145-166)
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Alterations in the Expression of Insulin-Like Growth Factors and Their Binding Proteins in Lung Cancer – Carrie M. Coleman, Adda Grimberg (Pages 167-186)
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Screening of Mutations in the ras Family of Oncogenes by Polymerase Chain Reaction-Based Ligase Chain Reaction – Alfredo MartÍnez, Teresa A. Lehman, Rama Modali, James L. Mulshine (Pages 187-200)
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Assays for Raf-1 Kinase Phosphorylation and Activity in Human Small Cell Lung Cancer Cells – Rajani K. Ravi, Barry D. Nelkin (Pages 201-210)
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γ-Glutamylcysteine Synthetase in Lung Cancer – Kristiina Järvinen, Ylermi Soini, Vuokko L. Kinnula (Pages 211-222)
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Localization of Cyclooxygenase-2 Protein Expression in Lung Cancer Specimens by Immunohistochemical Analysis – Sarah A. Wardlaw, Thomas H. March (Pages 223-230)
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Non-RI Protocols for L-myc Allelotyping and Deletion Mapping of Chromosome 1p in Primary Lung Cancers – Keiko Hiyama, Ciro Mendoza, Eiso Hiyama (Pages 231-239)
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Intercellular Adhesion Molecules (ICAM-1, VCAM-1, and LFA-1) in Adenocarcinoma of Lung – Armando E. Fraire, Bruce A. Woda, Louis Savas, Zhong Jiang (Pages 243-249)
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MUC1 Expression in Lung Cancer – Eva Szabo (Pages 251-258)
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Altered Surface Markers in Lung Cancer
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