Lehninger Principles of Biochemistry 6th Edition by David Nelson, Michael Cox ISBN 1429234148 9781429234146

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ISBN 10: 1429234148
ISBN 13: 9781429234146
Author: David Nelson, Michael Cox

Lehninger Principles of Biochemistry 6th Edition Table of contents:

1. The Foundations of Biochemistry

• The Scope of Biochemistry
• The Chemical Basis of Life
• Water, pH, and Buffers
• The Importance of Carbon in Biochemical Systems
• The Role of Energy in Biochemical Reactions

2. Amino Acids and Proteins

• The Structure and Properties of Amino Acids
• Peptide Bonds and Protein Structure
• Protein Folding and Stability
• Enzyme Structure and Function
• Protein Purification and Analysis
• Diseases Caused by Protein Misfolding

3. Enzymes: Structure, Kinetics, and Regulation

• Enzyme Structure and Mechanism of Action
• Enzyme Kinetics: Michaelis-Menten and Allosteric Models
• Regulation of Enzyme Activity
• Inhibition and Activation of Enzymes
• Enzyme Catalysis in Metabolic Pathways

4. Nucleic Acids and the Flow of Genetic Information

• The Structure and Function of DNA and RNA
• DNA Replication and Repair
• Transcription and RNA Processing
• Translation and Protein Synthesis
• Regulation of Gene Expression

5. Bioenergetics and Metabolism

• Principles of Thermodynamics in Biochemistry
• ATP and Cellular Energy Transfer
• Overview of Metabolic Pathways
• Coupled Reactions and Metabolic Control
• Metabolic Integration and Regulation

6. Carbohydrate Metabolism

• Glycolysis: Pathways, Regulation, and Energetics
• The Citric Acid Cycle
• Oxidative Phosphorylation and ATP Synthesis
• Glycogen Metabolism and Disorders
• Gluconeogenesis and Metabolic Control

7. Lipid Metabolism

• Lipid Structure and Function
• Fatty Acid Metabolism: Beta-Oxidation and Biosynthesis
• Synthesis of Membrane Lipids
• Cholesterol Metabolism
• Lipoproteins and Their Role in Lipid Transport

8. Nitrogen Metabolism and the Urea Cycle

• Amino Acid Metabolism: Transamination and Deamination
• The Urea Cycle: Pathway and Regulation
• Synthesis and Catabolism of Nonessential Amino Acids
• Disorders of Nitrogen Metabolism

9. Molecular Biology of the Cell

• The Cell: Structure and Function
• The Role of Organelles in Cellular Processes
• Signal Transduction and Cell Communication
• Mechanisms of Cellular Regulation
• The Cytoskeleton and Cell Division

10. Membrane Structure and Function

• The Fluid Mosaic Model of Membranes
• Membrane Transport: Passive and Active Processes
• Ion Channels and Transporters
• Membrane Proteins and Their Functions
• Membrane Lipids and Their Role in Cell Signaling

11. The Biochemistry of Signal Transduction

• Receptors and Signal Molecules
• G-Protein-Coupled Receptors (GPCRs)
• Enzyme-Linked Receptors
• Intracellular Signaling Pathways
• Hormonal Regulation and Second Messengers

12. Photosynthesis and Plant Biochemistry

• Light Reactions and the Photosynthetic Electron Transport Chain
• The Calvin Cycle: Carbon Fixation and Sugar Synthesis
• Regulation of Photosynthesis
• The Role of Chloroplasts in Energy Production
• Photosynthesis in Different Organisms

13. The Molecular Basis of Cancer

• Cellular Mechanisms of Cancer
• Oncogenes and Tumor Suppressors
• Signal Transduction Pathways in Cancer
• The Role of Metabolism in Cancer Cells
• Cancer Therapy and Chemotherapy

14. Clinical Biochemistry and Biotechnology

• Biochemical Markers in Disease Diagnosis
• Clinical Applications of Metabolic Pathways
• Recombinant DNA Technology and Biotechnology
• Enzyme Therapy and Protein Engineering
• Gene Therapy and Molecular Medicine

15. Advanced Topics in Biochemistry

• Structural Biology: X-ray Crystallography and NMR
• Bioinformatics and Systems Biology
• Metabolomics and its Applications
• Protein-Protein Interactions and Networks
• The Future of Biochemistry in Medicine and Biotechnology

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