ISE EBook Online Access for Pharmacology An Introduction 8th Edition by Henry Hitner, Barbara Nagie, Michele Kaufman, Hannath Ariel, Yael Lalehzarzadeh ISBN B09HBSTHZ2 9781260021820

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ISBN 10: B09HBSTHZ2
ISBN 13: 9781260021820
Author: Henry Hitner, Barbara Nagie, Michele Kaufman, Hannath Ariel, Yael Lalehzarzadeh

ISE EBook Online Access for Pharmacology An Introduction 8th Edition Table of contents:

Chapter 1: Overview of Pharmacology

• Definition and Scope of Pharmacology
• History and Development of Pharmacology
• The Role of Pharmacologists in Healthcare
• Pharmacology and the Drug Development Process
• Pharmacokinetics vs. Pharmacodynamics: A Brief Introduction

Chapter 2: Principles of Drug Action

• Drug Receptors and Signal Transduction
• Agonists, Antagonists, and Partial Agonists
• Dose-Response Relationship
• Therapeutic Window and Drug Potency
• Drug-Drug Interactions

Chapter 3: Drug Absorption, Distribution, Metabolism, and Excretion (ADME)

• Absorption of Drugs: Routes and Mechanisms
• Distribution of Drugs: Volume of Distribution and Blood-Brain Barrier
• Metabolism: Phase I and Phase II Reactions
• Excretion: Renal and Hepatic Clearance
• Factors Affecting ADME: Age, Disease, Genetics, and Diet

Chapter 4: Pharmacokinetics: Mathematical Models and Concepts

• Kinetics of Drug Absorption and Elimination
• First-Order vs. Zero-Order Kinetics
• Half-Life and Drug Dosing
• Steady-State Concentration
• Bioavailability and Bioequivalence

Chapter 5: Pharmacodynamics: Mechanisms of Drug Action

• Dose-Response Curves and Efficacy vs. Potency
• Pharmacological Targets: Enzymes, Ion Channels, Transporters
• Signal Transduction Pathways
• Therapeutic and Toxic Effects
• Tolerance and Dependence

Chapter 6: Autonomic Nervous System and Pharmacology

• Overview of the Autonomic Nervous System
• Sympathetic and Parasympathetic Divisions
• Adrenergic and Cholinergic Drugs
• Drugs Acting on Autonomic Receptors
• Clinical Applications and Side Effects of Autonomic Drugs

Chapter 7: Cardiovascular Pharmacology

• Drugs Affecting Blood Pressure: Antihypertensives
• Drugs for Heart Failure and Arrhythmias
• Antianginal Medications
• Anticoagulants, Antiplatelets, and Fibrinolytics
• Clinical Uses and Side Effects in Cardiovascular Pharmacology

Chapter 8: Pharmacology of the Central Nervous System

• Neurotransmitters and Their Role in CNS Pharmacology
• Antidepressants and Antianxiety Drugs
• Antipsychotics and Mood Stabilizers
• Analgesics: Opioids, Non-Opioid Pain Relievers
• Anesthetics: General and Local
• Drugs for Epilepsy and Neurodegenerative Diseases

Chapter 9: Respiratory Pharmacology

• Drugs for Asthma and Chronic Obstructive Pulmonary Disease (COPD)
• Bronchodilators and Anti-inflammatory Agents
• Antihistamines and Decongestants
• Mucolytics and Expectorants
• The Role of Pharmacology in Respiratory Therapy

Chapter 10: Renal Pharmacology

• Diuretics: Mechanisms and Clinical Use
• Drugs Affecting Renal Function
• Renal Failure and Pharmacological Management
• Electrolyte Balance and Correction
• Pharmacokinetics in Renal Impairment

Chapter 11: Endocrine Pharmacology

• Hormones and Hormone Receptors
• Insulin and Oral Antidiabetic Agents
• Thyroid and Parathyroid Drugs
• Drugs for Adrenal Disorders
• Sex Hormones and Contraceptives
• Growth Hormone and Related Therapies

Chapter 12: Gastrointestinal Pharmacology

• Drugs for Acid-Peptic Disorders: Antacids, H2 Blockers, and PPIs
• Antiemetics and Antidiarrheals
• Laxatives and Drugs for Constipation
• Drugs for Inflammatory Bowel Disease (IBD)
• Pharmacotherapy of Hepatic and Pancreatic Disorders

Chapter 13: Antimicrobial Pharmacology

• Antibiotics: Mechanisms and Resistance
• Antivirals, Antifungals, and Antiparasitics
• Antimicrobial Stewardship
• Chemotherapy and Anticancer Drugs
• Emerging Infectious Diseases and Pharmacology

Chapter 14: Toxicology and Adverse Drug Reactions

• Types of Adverse Drug Reactions: Allergic, Idiosyncratic, and Dose-Dependent
• Drug Toxicity and Organ-Specific Effects
• Monitoring Drug Safety
• Drug-Induced Liver Injury and Renal Toxicity
• Pharmacovigilance and Reporting Systems

Chapter 15: Drug Development and Regulation

• Phases of Clinical Trials: Preclinical to Post-Marketing
• Regulatory Agencies: FDA, EMA, and Global Regulations
• The Role of Pharmacology in Drug Design
• Good Manufacturing Practices (GMP) and Drug Approval
• Ethical Issues in Drug Development

Chapter 16: Personalized Medicine and Pharmacogenomics

• Principles of Pharmacogenetics
• Drug Response Variability and Genetic Factors
• Clinical Applications of Pharmacogenomics
• The Future of Precision Medicine in Pharmacology
• Ethical and Regulatory Issues in Pharmacogenomics

Chapter 17: Drug Abuse and Dependence

• Drugs of Abuse: Classification and Mechanisms
• Pharmacological Treatment of Substance Use Disorders
• The Neurobiology of Addiction
• Pharmacological Approaches to Managing Withdrawal and Cravings
• Policy, Prevention, and Harm Reduction in Drug Abuse

Chapter 18: Clinical Pharmacology and Therapeutic Decision-Making

• Role of Clinical Pharmacologists in Patient Care
• Pharmacotherapy: Choosing the Right Drug for the Right Patient
• Drug Monitoring and Therapeutic Drug Levels
• Interactions Between Drugs, Diseases, and Genetic Factors
• Case Studies in Clinical Pharmacology

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