Genomic Medicine A Practical Guide 1st edition by Laura Tafe 9783030229221 303022922X

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ISBN 10: 303022922X
ISBN 13: 9783030229221 
Author: Laura J. Tafe

The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest in molecular pathology and biomarkers. The book covers many aspects of molecular diagnostics, from techniques to applications and comprehensive summaries of the current molecular biomarkers of critical importance in solid and liquid tumors. Attention is also specifi cally devoted to bioinformatics and next generation sequencing, as well as pre-analytical issues that must be considered for accurate interpretation of molecular results in the context of overall patient care. This text focuses on clinical utility and validity and serves as an “owner’s manual” in Genomic Diagnostics for the practicing pathologist, pathology fellows and residents and other health care providers. Physicians will find this book invaluable as a quick reference for current molecular testing modalities and guidelines, tumor board preparation, deciding which test to order and interpreting genomic laboratory results. In addition, it is an accessible for trainees as a board review preparation reference.

Genomic Medicine A Practical Guide 1st Table of contents:

Part I. General Concepts

1. Pre-analytics, Current Testing Technologies, and Limitations of Testing

2. Next-Generation Sequencing

3. Cell-Free DNA Testing

4. Role of Bioinformatics in Molecular Medicine

5. Interpreting Genomic Reports

Part II. Applications in Solid Tumors

6. Lung Carcinoma

7. GI Including GIST

8. Breast

9. Genitourinary Tumors

10. Gynecologic Malignancies

11. Sarcomas

12. Salivary Gland Carcinomas

13. Sinonasal Carcinomas

Part III. Applications in Hematopathology

14. Acute Myeloid Neoplasms

15. Chronic Myeloid Neoplasms

16. Lymphomas

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