Sale!

Gene Mapping Discovery and Expression methods and protocols 1st Edition by Minou Bina ISBN 1588295753 9781588295750

Name: Gene Mapping Discovery and Expression methods and protocols 1st Edition by Minou Bina ISBN 1588295753 9781588295750
SKU: EB-13014
Availability: InStock

Original price was: $50.00.Current price is: $35.00.

Authors:Bina, Minou , Series:Pathology [15] , Tags:Pathology , Author sort:Bina, Minou , Languages:Languages:eng , Published:Published:Oct 2007 , Publisher:Humana Press , Comments:Completion of the sequence of the human genome represents an unpar- leled achievement in the historyof biology. The project has produced nearly complete, highly accurate, and comprehensive sequences of genomes of s- eral organisms including human, mouse, drosophila, and yeast. Furthermore, the development of high-throughput technologies has led to an explosion of projects to sequence the genomes of additional organisms including rat, chimp, dog, bee, chicken, and the list is expanding. The nearly completed draft of genomic sequences from numerous species has opened a new era of research in biology and in biomedical sciences. In keeping with the interdisciplinary nature of the new scientific era, the chapters in Gene Mapping, Discovery, and Expression: Methods and Protocols recapitulate the necessity of integration of experimental and computational tools for solving – portant research problems. The general underlying theme of this volume is DNA sequence-based technologies. At one level, the book highlights the importance of databases, genome-browsers, and web-based tools for data access and ana- sis. More specifically, sequencing projects routinely deposit their data in p- licly available databases including GenBank, at the National Center of Biotechnology (NCBI) in the United States; EMBL, maintained by the European Bioinformatics Institute; and DDBJ, the DNA Data Bank of Japan. Currently, several browsers offer facile access to numerous genomic DNA sequences for gene mapping and data retrieval.

SKU: EB-13014 Category: eBook PDF Tags: Discovery, Expression, Gene Mapping, Minou Bina

Description

Gene Mapping Discovery and Expression methods and protocols 1st Edition by Minou Bina – Ebook PDF Instant Download/Delivery. 1588295753 ,9781588295750
Full download Gene Mapping Discovery and Expression methods and protocols 1st Edition after payment

Product details:
ISBN 10: 1588295753
ISBN 13: 9781588295750
Author: Minou Bina

Completion of the sequence of the human genome represents an unpar- leled achievement in the history of biology. The project has produced nearly complete, highly accurate, and comprehensive sequences of genomes of s- eral organisms including human, mouse, drosophila, and yeast. Furthermore, the development of high-throughput technologies has led to an explosion of projects to sequence the genomes of additional organisms including rat, chimp, dog, bee, chicken, and the list is expanding. The nearly completed draft of genomic sequences from numerous species has opened a new era of research in biology and in biomedical sciences. In keeping with the interdisciplinary nature of the new scientific era, the chapters in Gene Mapping, Discovery, and Expression: Methods and Protocols recapitulate the necessity of integration of experimental and computational tools for solving – portant research problems. The general underlying theme of this volume is DNA sequence-based technologies. At one level, the book highlights the importance of databases, genome-browsers, and web-based tools for data access and ana- sis. More specifically, sequencing projects routinely deposit their data in p- licly available databases including GenBank, at the National Center of Biotechnology (NCBI) in the United States; EMBL, maintained by the European Bioinformatics Institute; and DDBJ, the DNA Data Bank of Japan. Currently, several browsers offer facile access to numerous genomic DNA sequences for gene mapping and data retrieval.

Gene Mapping Discovery and Expression methods and protocols 1st Edition Table of contents:

Chapter 1: Introduction to Gene Mapping

Overview of Gene Mapping
History and Evolution of Gene Mapping Techniques
Types of Gene Mapping: Physical and Genetic Maps
The Importance of Gene Mapping in Genomics
Key Concepts in Gene Discovery and Expression

Chapter 2: Methods for Mapping Genes

Classical Genetic Mapping Techniques
Molecular Markers in Gene Mapping
Restriction Fragment Length Polymorphism (RFLP) Mapping
Amplified Fragment Length Polymorphism (AFLP) and Simple Sequence Repeat (SSR) Markers
Quantitative Trait Locus (QTL) Mapping
Whole Genome Association Studies (GWAS)

Chapter 3: Chromosomal Mapping and Cytogenetic Techniques

Cytogenetic Approaches in Gene Mapping
Fluorescence In Situ Hybridization (FISH) for Chromosome Mapping
Spectral Karyotyping (SKY) and Comparative Genomic Hybridization (CGH)
Chromosome Conformation Capture (3C) and Related Techniques
High-Resolution Chromosome Mapping

Chapter 4: Next-Generation Sequencing (NGS) and Gene Mapping

Introduction to NGS Technologies in Gene Mapping
Whole Genome Sequencing (WGS) and Exome Sequencing
Mapping Genomic Variants with NGS Data
Mapping Genes in Complex Genomes Using NGS
Analysis of Structural Variants and Copy Number Variations (CNVs)

Chapter 5: Gene Expression Analysis and Profiling

Overview of Gene Expression and Its Regulation
RNA Extraction and Purification Methods
Quantitative PCR for Gene Expression Quantification
Microarray Analysis for Gene Expression Profiling
RNA-Seq: High-Throughput Sequencing for Transcriptome Analysis
Comparative Gene Expression Analysis: Normal vs. Disease States

Chapter 6: Functional Gene Mapping

Approaches to Functional Genomics
Gene Knockout and Knockdown Techniques: CRISPR/Cas9 and RNA Interference (RNAi)
Functional Annotation of Genes and Pathways
Gene Editing for Functional Gene Mapping
Transgenic Models in Functional Gene Discovery

Chapter 7: Physical Mapping Techniques

Radiation Hybrid Mapping and Mapping Using Bacterial Artificial Chromosomes (BACs)
Chromosome Walking and Cloning of Genes
High-Throughput Physical Mapping Techniques
Contig Assembly and Scaffold Construction in Large Genomes
Integration of Physical and Genetic Maps

Chapter 8: Advanced Technologies for Gene Discovery

Single-Cell Gene Expression Profiling
DNA Methylation and Epigenetics in Gene Mapping
Chromatin Immunoprecipitation (ChIP) for Gene Mapping
Proteomics in Gene Discovery: Protein-Protein Interactions
Metabolomics and its Role in Gene Expression and Mapping

Chapter 9: Computational Tools for Gene Mapping and Expression Analysis

Bioinformatics Software for Gene Mapping and Annotation
Tools for GWAS, QTL Analysis, and NGS Data Interpretation
Pathway and Network Analysis in Gene Expression Studies
Genome Browsers and Visualization Tools
Data Integration from Various Omics Approaches

Chapter 10: Gene Mapping in Model Organisms

Model Organisms for Gene Mapping: Yeast, Drosophila, Zebrafish, Mice, and Others
Comparative Genomics in Gene Discovery
Gene Mapping in Non-model Organisms
Applications of Gene Mapping in Agricultural and Environmental Research

Chapter 11: Clinical Applications of Gene Mapping

Gene Mapping in Human Disease: Identifying Disease-Specific Genes
Gene Mapping for Personalized Medicine and Pharmacogenomics
Gene Therapy and Gene Editing for Disease Treatment
Ethical Issues in Gene Mapping and Genetic Data Interpretation
The Future of Gene Mapping in Medicine and Biotechnology

Chapter 12: Challenges and Future Directions in Gene Mapping

Current Limitations in Gene Mapping Technologies
Addressing Complex Traits and Polygenic Inheritance
Advances in Long-Read Sequencing and Its Impact on Gene Mapping
Integrating Epigenetic, Transcriptomic, and Proteomic Data for Comprehensive Mapping
The Future of Precision Medicine and Functional Genomics

People also search for Gene Mapping Discovery and Expression methods and protocols 1st Edition:

gene mapping explained

gene mapping example

gene mapping example problems

gene mapping and linkage

Gene Mapping Discovery and Expression methods and protocols 1st Edition by Minou Bina ISBN 1588295753 9781588295750

You may also like…

Login