Fundamentals of Psychopharmacology 2nd Edition by Brian Leonard ISBN 0471961159 9780471961154
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Authors:Brian E. Leonard , Series:Pharmacology [5] , Tags:Medical; Pharmacology; General , Author sort:Leonard, Brian E. , Ids:9780470842379 , Languages:Languages:eng , Published:Published:May 2004 , Publisher:John Wiley & Sons , Comments:Comments:Treatment with drugs is fundamental to modern therapy of psychiatric disorders. The number of disorders responsive to drug treatment is increasing, reflecting the extensive synthesis of novel compounds and the greater understanding of the aetiology of the disorders. This third edition provides new and updated material, including an additional chapter on clinical trials and their importance in assessing the efficacy and safety of psychotropic drugs. As molecular biology and imaging techniques are of increasing importance to basic and clinical neuroscience, these areas have also been extended to illustrate their relevance to our understanding of psychopharmacology. This book is essential reading for undergraduates in pharmacology and the neurosciences, postgraduate neuropharmacologists, psychiatrists in training and in practice and medical researchers. Reviews of the Second Edition “…this text is eminently readable, well researched, and probably the best of its kind. The book is well worth buying and anyone who claims to know anything about psychopharmacology will be expected to have a heavily annotated copy.” Irish Journal of Psychological Medicine “…[this is] a very good book, especially suited to those interested in psychopharmacologic research and psychiatric residency in training.” Journal of Chemical Neuroanatomy
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ISBN 10: 0471961159
ISBN 13: 9780471961154
Author: Brian Leonard
Fundamentals of Psychopharmacology 2nd Edition Table of contents:
Chapter 1: Introduction to Psychopharmacology
- Definition and Scope of Psychopharmacology
- Historical Overview of Psychopharmacology
- Psychopharmacology in the Context of Psychiatry
- Key Principles: Neurotransmission and Drug Action
Chapter 2: Basic Neurochemistry and Neurotransmitter Systems
- Overview of Neurotransmitter Functions and Mechanisms
- Major Neurotransmitter Systems: Dopamine, Serotonin, Norepinephrine, Glutamate, GABA
- Neurotransmitter Receptors and Their Role in Drug Action
- Signal Transduction Pathways in Psychopharmacology
Chapter 3: The Blood-Brain Barrier and Drug Distribution
- The Blood-Brain Barrier and Its Impact on Drug Action
- Pharmacokinetics: Absorption, Distribution, Metabolism, and Excretion (ADME)
- Factors Affecting Drug Distribution in the Brain
- Drug Half-Life and Its Relevance to Clinical Dosing
Chapter 4: Antidepressants: Mechanisms and Clinical Use
- Overview of Depression and Its Neurochemical Basis
- Classes of Antidepressants: SSRIs, SNRIs, MAOIs, Tricyclic Antidepressants
- Mechanisms of Action and Side Effects
- Clinical Applications and Therapeutic Response
Chapter 5: Antipsychotic Drugs
- The Role of Antipsychotics in Treating Schizophrenia and Other Psychoses
- Typical vs. Atypical Antipsychotics: Mechanisms and Differences
- Dopamine and Serotonin in Antipsychotic Drug Action
- Side Effects and Management of Antipsychotic Treatment
Chapter 6: Anxiolytic Drugs
- The Neurobiology of Anxiety and Stress
- Benzodiazepines: Mechanism of Action and Clinical Use
- Non-Benzodiazepine Anxiolytics: Buspirone and Others
- Emerging Treatments for Anxiety Disorders
Chapter 7: Mood Stabilizers in Bipolar Disorder
- The Pharmacological Treatment of Bipolar Disorder
- Lithium: Mechanisms of Action, Efficacy, and Side Effects
- Anticonvulsants as Mood Stabilizers: Valproate, Lamotrigine
- Newer Agents in the Treatment of Bipolar Disorder
Chapter 8: Stimulants and Attention-Deficit Hyperactivity Disorder (ADHD)
- The Neurochemistry of ADHD and Stimulant Treatment
- Mechanisms of Action of Methylphenidate and Amphetamines
- Non-Stimulant Medications for ADHD
- Clinical Considerations in ADHD Pharmacotherapy
Chapter 9: The Role of Neuroplasticity in Psychopharmacology
- Neuroplasticity and Its Impact on Mental Health
- Antidepressant Effects on Neurogenesis
- Psychotropic Medications and Brain Structure/Function
- Long-Term Effects of Psychotropic Drugs on the Brain
Chapter 10: Drug Addiction and Substance Use Disorders
- The Neurobiology of Addiction
- Pharmacological Treatments for Substance Use Disorders
- Opioids, Alcohol, and Nicotine: Mechanisms and Treatments
- Novel Approaches to Addiction Treatment and Prevention
Chapter 11: Cognitive Enhancers and Nootropics
- The Growing Interest in Cognitive Enhancers
- Mechanisms of Action of Nootropic Drugs
- Clinical and Ethical Considerations in the Use of Cognitive Enhancers
- The Future of Nootropics in Psychopharmacology
Chapter 12: Psychopharmacology of Sleep Disorders
- Neurochemical Regulation of Sleep and Wakefulness
- Pharmacological Treatment of Insomnia and Hypersomnia
- Melatonin, Benzodiazepines, and Other Sleep Medications
- Psychopharmacological Approaches to Circadian Rhythm Disorders
Chapter 13: Pediatric and Geriatric Psychopharmacology
- Developmental Aspects of Psychopharmacology in Children
- Psychopharmacological Treatments for Pediatric Psychiatric Disorders
- Age-Related Changes in Drug Metabolism and Response in Older Adults
- Special Considerations for Psychopharmacology in the Elderly
Chapter 14: Side Effects and Safety in Psychopharmacology
- Adverse Effects of Psychotropic Medications
- Managing Side Effects: Strategies and Considerations
- Drug Interactions in Psychopharmacology
- Clinical Monitoring and Patient Safety
Chapter 15: Psychopharmacology in Clinical Practice
- Principles of Psychopharmacologic Treatment
- Diagnosis and Therapeutic Decision-Making
- Case Studies in Psychopharmacology
- The Role of the Psychiatrist and Pharmacist in Treatment
Chapter 16: Future Trends in Psychopharmacology
- Advances in Psychopharmacologic Drug Development
- Personalized Medicine and Pharmacogenomics in Psychiatry
- Neurostimulation and Novel Therapeutics
- Emerging Research and Technologies in Psychopharmacology
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