Functional Ultrastructure Atlas of Tissue Biology and Pathology 3rd edition by Margit Pavelka, Jürgen Roth ISBN 3709118298 978-3709118290

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ISBN 10:  3709118298 
ISBN 13: 978-3709118290
Author:   Margit Pavelka, Jürgen Roth 

Functional Ultrastructure Atlas of Tissue Biology & Pathology 3rd Table of contents:

 

1. Introduction to Ultrastructural Techniques

   • Overview of electron microscopy and its role in tissue biology and pathology.
   • Techniques for preparing tissue samples for ultrastructural analysis.
   • Imaging methods and interpretation of ultrastructural data.

2. Basic Ultrastructure of Cells and Tissues

   • Detailed images and descriptions of cellular organelles and structures.
   • Membranes, cytoplasm, nucleus, and cytoskeleton.
   • Special structures in different types of cells (e.g., muscle cells, neurons).

3. Functional Ultrastructure of Epithelial Tissues

   • Ultrastructural features of different types of epithelial cells (e.g., squamous, columnar, and transitional epithelium).
   • Specialized structures like cilia, microvilli, and tight junctions.
   • Pathological changes in epithelial tissues (e.g., neoplasia, dysplasia).

4. Functional Ultrastructure of Connective Tissues

   • Ultrastructure of fibroblasts, collagen fibers, elastin, and ground substance.
   • Cartilage and bone ultrastructure.
   • Pathological alterations in connective tissue, including fibrosis and inflammation.

5. Muscle Tissue Ultrastructure

   • Ultrastructural features of skeletal, cardiac, and smooth muscle cells.
   • Sarcomere structure, myofilaments, and muscle contraction mechanisms.
   • Changes in muscle tissue due to disease (e.g., muscular dystrophy, cardiac hypertrophy).

6. Nervous Tissue Ultrastructure

   • Neurons, glial cells, and synaptic structures.
   • Ultrastructure of the blood-brain barrier and neurovascular unit.
   • Pathological alterations in the nervous system, including neurodegenerative diseases and tumors.

7. Vascular Ultrastructure

   • Endothelial cell structure and function.
   • Smooth muscle cells in blood vessel walls.
   • Pathological changes in blood vessels, such as atherosclerosis, aneurysms, and inflammation.

8. Functional Ultrastructure of the Liver

   • Hepatocyte ultrastructure and the structure of liver lobules.
   • Blood flow through the liver and bile formation.
   • Pathological changes in liver tissue, such as cirrhosis, hepatitis, and fatty liver disease.

9. Functional Ultrastructure of the Kidney

   • Ultrastructure of glomeruli, renal tubules, and collecting ducts.
   • Mechanisms of filtration, reabsorption, and secretion.
   • Pathological changes in kidney tissue, including glomerulonephritis and nephrosclerosis.

10. Functional Ultrastructure of the Lung

    • Ultrastructure of alveoli, capillaries, and airways.
    • Mechanisms of gas exchange and lung compliance.
    • Pathological changes in lung tissue, including emphysema, fibrosis, and infections.

11. Functional Ultrastructure of the Endocrine Glands

    • Ultrastructure of pituitary, thyroid, parathyroid, adrenal, and pancreas.
    • Hormone secretion mechanisms and their regulation.
    • Pathological conditions affecting endocrine glands, such as tumors and autoimmune diseases.

12. Functional Ultrastructure of the Gastrointestinal Tract

    • Ultrastructure of the mucosa, muscularis, and serosa in the GI tract.
    • Absorption and secretion in the intestines.
    • Pathological changes in the GI system, including inflammatory bowel disease and gastrointestinal cancers.

13. Functional Ultrastructure of the Skin

    • Epidermal and dermal structure.
    • Specialized structures, including hair follicles and sweat glands.
    • Pathological alterations in the skin, such as dermatitis, psoriasis, and skin cancer.

14. Functional Ultrastructure of the Reproductive System

    • Ultrastructure of the male and female reproductive organs.
    • Gametogenesis, fertilization, and early embryonic development.
    • Pathological conditions, including infertility, tumors, and hormonal disorders.

15. Emerging Technologies in Ultrastructure

    • Advances in imaging techniques such as cryo-EM and super-resolution microscopy.
    • Future trends in ultrastructural pathology.
    • Integrating molecular techniques with ultrastructural analysis.

16. Case Studies and Diagnostic Challenges

    • Case-based approach to interpreting ultrastructural features in pathology.
    • Common diagnostic challenges and how ultrastructure can provide solutions.
    • Review of key learning points.

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