Frozen Section Pathology Diagnostic Challenges 1st edition by Alain Borczuk, Rhonda Yantiss, Brian Robinson, Theresa Scognamiglio, Timothy ISBN 3030713075 978-3030713072

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Product details:

ISBN 10: 3030713075
ISBN 13: 978-3030713072
Author: Alain Borczuk, Rhonda Yantiss, Brian Robinson, Theresa Scognamiglio, Timothy 

This book provides guidance regarding the approach to common scenarios encountered in the frozen section laboratory while underscoring diagnostic pitfalls and providing the proper level of diagnostic information to ensure clear communication. Given the use of frozen section in molecular and research pathology, the text also serves as a guide for morphologic examination. Written by experts in the field, the book is organized according to organ system with additional chapters discussing the roles of digital pathology and molecular assays. Each chapter is extensively illustrated to highlight key points that facilitate interpretation and highlight areas for potential error. The goal of this book is to help trainees understand the need for mastery of this unique diagnostic tool, and to aid pathologists who cover frozen section convert practical information provided into diagnostic improvements.
Frozen Section Pathology is a comprehensive and state-of-the-art review and serves as a valuable resource for the general surgical pathologist with frozen section responsibilities as well as surgeons who regularly utilize frozen section.

Frozen Section Pathology Diagnostic Challenges 1st Table of contents:

• Introduction to Frozen Section Pathology

  • Overview of the frozen section technique.
  • Historical context and importance in surgical pathology.
  • Indications for frozen section use during surgeries.

• Principles of Frozen Section Preparation and Processing

  • The science and methodology behind preparing frozen tissue samples.
  • Challenges with tissue handling, freezing, and sectioning.
  • Equipment used in frozen section analysis.

• Diagnostic Challenges in Frozen Section Pathology

  • Common diagnostic pitfalls during frozen section examination.
  • Artifacts and their impact on diagnosis.
  • Factors affecting the accuracy of frozen section diagnosis.

• Frozen Section and Cancer Diagnosis

  • Role of frozen section in detecting malignancy during surgery.
  • Diagnostic challenges in various cancers (e.g., breast, lung, gastrointestinal).
  • Interpretation of margins and tumor staging.

• Non-Neoplastic Conditions in Frozen Section

  • Identifying and diagnosing benign conditions in frozen section samples.
  • Inflammatory diseases, infections, and fibrous lesions.
  • Challenges in differentiating benign from malignant conditions.

• Frozen Section in Pediatric Pathology

  • Special considerations when performing frozen sections in pediatric patients.
  • Common pediatric pathologies encountered and diagnostic challenges.

• Technical Challenges in Frozen Section

  • Handling difficult tissue types (e.g., fatty tissues, calcifications).
  • Maintaining sample integrity under time constraints.
  • Preventing diagnostic errors in rapid processing.

• Case Studies and Diagnostic Dilemmas

  • Real-world case studies illustrating diagnostic challenges encountered with frozen sections.
  • How these cases were managed and lessons learned.

• Recent Advances and Future Directions in Frozen Section Pathology

  • Technological advancements to improve frozen section accuracy.
  • The role of molecular techniques and digital pathology in frozen section diagnosis.
  • Future trends in frozen section pathology.

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