Fanaroff and Martin Neonatal Perinatal Medicine 11th edition by Richard Martin, Avroy Fanaroff, Michele Walsh 9780323567107, 032356710X

Part 1: The Field of Neonatal-Perinatal Medicine

1. Growth of Neonatal Perinatal Medicine—A Historical Perspective

   • Perinatal Pioneers
   • The High-Risk Fetus and Perinatal Obstetrics
   • Midwives and Perinatal Care
   • Neonatal Resuscitation: Tales of Heroism and Desperation
   • Apgar and the Language of Asphyxia
   • Foundling Asylums and Infant Care
   • Saving Infants to Man the Army
   • An Ingenious Contrivance, the Couveuse, and Premature Baby Stations
   • Incubators, Baby Shows, and Origins of Neonatal Intensive Care Units
   • Supportive Care and Oxygen Therapy
   • Ventilatory Care: “Extended Resuscitation”
   • Supportive Care: Intravenous Fluid and Blood Transfusions
   • Tools and Supplies for Neonatal Intensive Care Units
   • Pediatric Surgery: Not for Rabbits Anymore
   • Global Neonatal Care
   • Medical Errors and “Patient Safety” as a New Discipline
   • Controlled Clinical Trials, Evidence-Based Medicine, and Research Networks
   • Future of Neonatal Research, Education, and Databases in the Internet Era
   • Some Famous High-Risk Infants
   • Acknowledgment
   • Key Points
   • References

2. Epidemiology for Neonatologists

   • Introduction
   • Common Epidemiologic Concepts
   • Health Statistics and Data Sources
   • Birth Data
   • Fetal Deaths
   • Infant Deaths
   • Pregnancy-Related Deaths
   • Maternal Morbidity
   • Neonatal Morbidity
   • Key Points
   • References

3. Medical Ethics in Neonatal Care

   • Principles in Medical Ethics
   • Autonomy
   • Beneficence
   • Nonmaleficence
   • Justice
   • Key Terms and Concepts
   • Clinical Applications in Specific Moral Problems
   • Collaborative, Procedural Framework for End-of-Life Decision Making
   • Specific Issues in End-of-Life Care
   • Palliative Care in the Neonatal Intensive Care Unit
   • Conflict Resolution When Consensus Cannot Be Reached
   • Ethics of Research in the Neonatal Intensive Care Unit
   • Ethical Responsibilities of Neonatal Physicians
   • Acknowledgment
   • Key Points
   • References

4. Legal Issues in Neonatal-Perinatal Medicine

   • Disclaimer
   • General Legal Principles
   • Malpractice
   • Live Birth
   • Handicapped Newborns
   • Providing Care Against Parents’ Wishes
   • Summary
   • Key Points
   • References

5. Evaluating and Improving the Quality and Safety of Neonatal Intensive Care

   • The Case for Improvement
   • Brief History of Industrial Quality Improvement
   • Definition and Conceptual Frameworks for Quality
   • Data and Methods for Quality Improvement
   • Quality and Safety Applied
   • Conclusion
   • Acknowledgments
   • Key Points
   • References

6. Simulation and Debriefing in Neonatal-Perinatal Medicine

   • Introduction
   • Simulation-Based Training in High-Risk Industries
   • Simulation-Based Training in Health Care
   • Simulation-Based Training in Neonatal-Perinatal Medicine
   • Debriefing Simulated Events
   • Debriefing Actual Clinical Events
   • Simulation-Based Assessment
   • Simulation-Based Research
   • Simulation as the Basis of Clinical Care
   • The Future of Simulation in Neonatal-Perinatal Medicine
   • Key Points
   • References

7. Practicing Evidence-Based Neonatal-Perinatal Medicine

   • Asking a Focused Clinical Question
   • Finding Evidence
   • Efficient Strategies for Searching for Evidence
   • Critically Appraising Evidence for Its Validity
   • Extracting the Data and Expressing the Effect of Treatment
   • Applying the Results to Patient Care
   • Promoting Evidence-Based Clinical Practice
   • Key Points
   • References

8. Perinatal and Neonatal Care in Developing Countries

   • Global Initiatives to Reduce Infant Mortality Rate and Neonatal Mortality Rate
   • Global Burden of Maternal and Neonatal Deaths
   • Causes of Global Maternal and Neonatal Mortality
   • Burden of Neonatal Sepsis
   • Evidence-Based Interventions to Reduce Maternal Mortality Rates, Neonatal Mortality Rates, and Infant Mortality Rates
   • The Impact of Progress
   • Strategies to Improve Global Neonatal and Perinatal Outcome
   • Summary
   • Acknowledgments
   • Key Points
   • References

9. Social and Economic Contributors to Neonatal Outcome in the United States

   • Epidemiology of Health Disparities in Neonatal and Perinatal Medicine
   • Social Determinants of Health
   • Interventions to Reduce Neonatal Health Outcome Disparities
   • Key Points
   • References

Part 2: The Fetus

10. Genetic Aspects of Perinatal Disease and Prenatal Diagnosis

• Principles of Inheritance
• Teratogens
• Congenital Anomalies and Ultrasonography
• Screening Modalities
• Future Directions for Non-Invasive Screening and Diagnosis
• Screening for Multifactorial Disorders
• Diagnostic Modalities
• Technical Advances in Molecular Cytogenetics
• Future Directions for Prenatal Diagnostic Testing
• Assisted Reproductive Technologies (ART)
• Genetic Evaluation and Counseling
• Key Points
• References

11. Perinatal Ultrasound

• Ultrasound Equipment
• Fetal Imaging Techniques
• Bioeffects and Safety
• Ethical Considerations
• Applications of Ultrasound Studies
• Pregnancy Evaluation
• Doppler Ultrasound
• Ultrasound-Guided Procedures
• Fetal Well-Being Assessment
• Fetal Anomalies
• Summary
• Key Points
• References

12. Estimation of Fetal Well-Being

• Introduction
• Antepartum Fetal Surveillance
• Evaluation of the Intrapartum Fetus
• Key Points
• References

13. Surgical Treatment of the Fetus

• Summary
• Fetal Access
• Anesthetic Considerations
• Anomalies Amenable to Fetal Surgery
• Conclusion
• Key Points
• References

14. Adverse Exposures to the Fetus and Neonate

• Exposures Not Concurrent With Pregnancy
• Maternal Exposures Concurrent With Pregnancy
• Pathways of Fetal Exposure
• Fetal Pharmacokinetics
• Specific Exposures
• Conclusions
• Key Points
• References

15. Intrauterine Growth Restriction

• Summary
• Definitions and Terminology
• The Health Burden of IUGR
• Classification of IUGR
• Etiology of IUGR
• Pathophysiology
• Antenatal Screening and Prenatal Management
• Prevention
• Postnatal Diagnosis of IUGR
• Postnatal Management
• Long-Term Consequences of IUGR
• Conclusions
• Key Points
• References

16. Developmental Origins of Adult Health and Disease

• Fetal Origins of Adult Disease Concept
• Postnatal Growth and Nutrition
• Mismatch Concept
• Placental Abnormalities and Association With Adult Disease
• Gestational Diabetes and Long-Term Metabolic Effects on Offspring
• Toxins, Endocrine Disrupters, and Micronutrient Metabolism (See Also Chapter 14)
• Epigenetics
• Translation to Neonatology
• Key Points
• References

Part 3: Pregnancy Disorders and Their Impact on the Fetus

17. Hypertensive Disorders of Pregnancy

• Classification of Hypertensive Disorders of Pregnancy
• Epidemiology of Preeclampsia
• Clinical Presentation of Preeclampsia
• Other Hypertensive Disorders of Pregnancy
• Prediction