Essentials of Kumar and Clark Clinical Medicine 6th Edition by Nicola Zammitt, Alastair OBrien, Parveen Kumar, Michael Clark ISBN 9780702066061 0702066060

1: Ethics and communication

Legally valid consent

Confidentiality

Communication

2: Infectious diseases

Common viral infections

Bacterial infections

Fever in the returned traveller

Miscellaneous viral infections

Gastroenteritis and food poisoningnd

Helminthic infections

Sexually transmitted infections

Human immunodeficiency virus

Therapeutics

3: Gastroenterology and nutrition

Gastroenterology

Symptoms of gastrointestinal disease

Investigation of gastrointestinal disease

The mouth

The oesophagus

The stomach and duodenum

Gastrointestinal bleeding

The small intestine

Miscellaneous small intestinal conditions

Inflammatory bowel disease

The colon and rectum

Diarrhoea

Functional bowel disorders

The acute abdomen

The peritoneum

Nutrition

Nutritional support

Disorders of bodyweight

Therapeutics

4: Liver, biliary tract and pancreatic disease

Liver biochemistry and liver function tests

Other investigations in liver and biliary disease

Symptoms and signs of liver disease

Jaundice

Hepatitis

Non-alcoholic fatty liver disease

Cirrhosis

Complications and effects of cirrhosis

Liver transplantation

Types of chronic liver disease and cirrhosis

Primary sclerosing cholangitis

Budd–Chiari syndrome

Liver abscess

Liver disease in pregnancy

Liver tumours

Gallstones

The pancreas

Carcinoma of the pancreas

Neuroendocrine tumours of the pancreas

5: Haematological disease

Anaemia

Haemolytic anaemia

Inherited haemolytic anaemias

Acquired haemolytic anaemia

Myeloproliferative disorders

The spleen

Blood transfusion

The white cell

Haemostasis and thrombosis

Thrombosis

Therapeutics

6: Malignant disease

Diagnosis of malignancy

Myeloablative therapy and haemopoietic stem cell transplantation

The lymphomas

The paraproteinaemias

Palliative medicine and symptom control

7: Rheumatology

The normal joint

Musculoskeletal symptoms

Common investigations in musculoskeketal disease

Common regional musculoskeletal problems

Back pain

Intervertebral disc disease

Osteoarthritis

Inflammatory arthritis

The seronegative spondyloarthritis

Crystal arthritis

Infection of bones and joints

Autoimmune rheumatic diseases

Systemic inflammatory vasculitis

Diseases of bone

Therapeutics

8: Water, electrolytes and acid–base balance

Water and electrolyte requirements

Body fluid compartments

Regulation of body fluid homeostasis

Plasma osmolality and disorders of sodium regulation

Disorders of potassium regulation

Disorders of magnesium regulation

Disorders of acid–base balance

Therapeutics

9: Renal disease

Presenting features of renal disease

Investigation of renal disease

Glomerular diseases

Nephrotic syndrome

Urinary tract infection

Tubulointerstitial nephritis

Hypertension and the kidney

Renal calculi and nephrocalcinosis

Urinary tract obstruction

Acute kidney injury

Chronic kidney disease

Renal replacement therapy

Cystic renal disease

Tumours of the kidney and genitourinary tract

Diseases of the prostate gland

Testicular tumour

Urinary incontinence

10: Cardiovascular disease

Common presenting symptoms of heart disease

Investigations in cardiac disease

The electrocardiogram

Cardiac arrhythmias

Heart failure

Ischaemic heart disease

Rheumatic fever

Valvular heart disease

Pulmonary heart disease

Myocardial disease

Cardiomyopathy

Pericardial disease

Systemic hypertension

Arterial and venous disease

Therapeutics for the cardiovascular system

Drugs for arrhythmias

Drugs for heart failure

Drugs affecting the renin–angiotensin system

Nitrates, calcium-channel blockers and potassium-channel activators

11: Respiratory disease

Basic structure of the respiratory system

Function of the respiratory system

Symptoms of respiratory disease

Investigation of respiratory disease

Smoking

Diseases of the upper respiratory tract

Diseases of the lower respiratory tract

Asthma

Pneumonia

Tuberculosis

Diffuse diseases of the lung parenchyma

Occupational lung disease

Carcinoma of the lung

Diseases of the chest wall and pleura

Disorders of the diaphragm

Therapeutics

12: Intensive care medicine

Acute disturbances of haemodynamic function (shock)

Respiratory failure

Acute respiratory distress syndrome (ARDS)

13: Clinical pharmacology and toxicology

Drug prescribing

Drug poisoning

Specific drug problems

Recreational drug use

14: Endocrine disease

Common presenting symptoms in endocrine disease

Pituitary hypersecretion syndromes

The thyroid axis

Male reproduction and sex

Female reproduction and sex

The glucocorticoid axis

Endocrinology of blood pressure control

The thirst axis

Disorders of calcium metabolism

Disorders of phosphate concentration

Disorders of temperature regulation

Therapeutics

15: Diabetes mellitus and other disorders of metabolism

Diabetes mellitus

Diabetic metabolic emergencies

Complications of diabetes

Special situations

Hypoglycaemia in the non-diabetic

Disorders of lipid metabolism

The porphyrias

Amyloidosis

Therapeutics

16: The special senses

The ear

The nose and nasal cavity

The throat

The eye

17: Neurology

Common neurological symptoms

Coordination of movement

The cranial nerves

Common investigations in neurological disease

Unconsciousness and coma

Stroke and cerebrovascular disease

Epilepsy and loss of consciousness

Movement disorders

Nervous system infection and inflammation

Brain tumours

Hydrocephalus

Headache, migraine and facial pain

Spinal cord disease

Degenerative neuronal diseases

Diseases of the peripheral nerves

Muscle diseases

Myotonias

Delirium

Therapeutics

18: Dermatology

Introduction

Skin and soft tissue infections

Cellulitis and erysipelas

Common skin conditions

Cutaneous signs of systemic disease

Other diseases affecting the skin

Bullous disease

Malignant skin tumours

Normal values

Dictionary of terms

Index