Epicardial Adipose Tissue From Cell to Clinic 1st Edition by Gianluca Iacobellis ISBN 9783030405700

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ISBN 10: 
ISBN 13: 9783030405700
Author: Gianluca Iacobellis

This book is the first authoritative and comprehensive volume dedicated to epicardial adipose tissue (EAT). It provides an up-to-date and highly illustrated synopsis of the anatomical, biomolecular, genetic, imaging features, and clinical applications of EAT and its role in cardiovascular disease.

It relays to the reader a contemporary view of the emerging interplay between the heart and adiposity-related diseases. In addition, this volume discusses the clinical implications and therapeutic targets of EAT in atrial fibrillation, heart failure and coronary artery disease.

Comprehensive yet focused, Epicardial Adipose Tissue: From Cell to Clinic is an essential resource for physicians, residents, fellows, and medical students in cardiology, endocrinology, primary care, and health promotion and disease prevention.

Epicardial Adipose Tissue From Cell to Clinic 1st Table of contents:

Chapter 1: Introduction to Epicardial Adipose Tissue

• Definition and Location of Epicardial Adipose Tissue
• Anatomy and Physiology of EAT
• Role of EAT in Cardiovascular Health
• Clinical Significance and Emerging Research

Chapter 2: Development and Biology of Epicardial Adipose Tissue

• Embryological Development of EAT
• Differentiation of Adipocytes in the Heart
• Genetic and Epigenetic Regulation of EAT
• Adipogenesis and Lipid Metabolism in EAT

Chapter 3: Molecular and Cellular Composition of EAT

• Types of Cells in EAT (Adipocytes, Fibroblasts, Macrophages, etc.)
• Cytokines and Growth Factors Secreted by EAT
• Adipokines and Their Role in Cardiovascular Disease
• Molecular Signaling Pathways in EAT Function

Chapter 4: Pathophysiology of Epicardial Adipose Tissue

• EAT and Cardiovascular Risk Factors
• EAT in Atherosclerosis and Coronary Artery Disease
• The Role of EAT in Inflammation and Metabolic Dysfunction
• Adiposity and Its Impact on Myocardial Function

Chapter 5: EAT as a Diagnostic Marker

• Imaging Techniques for EAT Assessment (CT, MRI, Echocardiography)
• EAT and Its Relationship with Obesity and Metabolic Syndrome
• EAT Thickness as a Risk Indicator in Cardiovascular Disease
• Biomarkers Associated with EAT for Clinical Use

Chapter 6: Epicardial Adipose Tissue in Cardiovascular Disease

• EAT in Heart Failure and Arrhythmias
• The Role of EAT in Coronary Artery Disease (CAD)
• EAT and Hypertension
• EAT and Acute Myocardial Infarction (MI)
• Influence of EAT on Myocardial Remodeling

Chapter 7: Clinical Implications and Therapeutic Strategies

• EAT Reduction: Surgical, Pharmacological, and Lifestyle Approaches
• EAT and Weight Loss: Effects on Cardiovascular Risk
• Pharmacotherapies Targeting EAT
• EAT and Personalized Cardiovascular Medicine

Chapter 8: Advances in EAT Research

• Stem Cells and Regenerative Medicine in EAT
• Animal Models in EAT Research
• Novel Insights into EAT and Its Role in Cardiac Disease
• EAT and Its Interaction with Other Organs

Chapter 9: Epicardial Adipose Tissue and Aging

• Age-Related Changes in EAT
• EAT and Age-Associated Cardiovascular Diseases
• Impact of Aging on EAT Function and Metabolism

Chapter 10: Future Directions in EAT Research and Clinical Practice

• Emerging Technologies in EAT Imaging and Monitoring
• Molecular Therapeutics Targeting EAT
• Prospects for EAT as a Biomarker for Precision Medicine
• Future Clinical Trials and Studies on EAT

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