Cell Engineering and Regeneration 1st edition by Jeffrey M. Gimble, Darja Marolt Presen, Richard O. C. Oreffo, Susanne Wolbank, Heinz Redl – Ebook PDF Instant Download/DeliveryISBN: 9783319088310
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Product details:
ISBN-13 : 9783319088310
Author : Jeffrey M. Gimble, Darja Marolt Presen, Richard O. C. Oreffo, Susanne Wolbank, Heinz Redl
This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.
Cell Engineering and Regeneration 1st Table of contents:
Overview of Cell Types Capable of Contributing to Skeletal Muscle Repair and Regeneration
Cells for Cartilage Regeneration
Periosteum Derived Cells in Skeletal Tissue Regeneration
Bone-Marrow-Derived Mesenchymal Stromal Cells: From Basic Biology to Applications in Bone Tissue Engineering and Bone Regeneration
Pancreatic Islet Beta-Cell Replacement Strategies
The Role of Schwann Cells in Peripheral Nerve Function, Injury, and Repair
Stem Cells: Umbilical Cord/Wharton’s Jelly Derived
Hair Follicle Stem Cells and Hair Regeneration
Muse Cells
Embryonic Stem Cells
Use of Xenogeneic Cells
Cell Culture and Cell Modulation
Cell Culture Conditions: Cultivation of Stem Cells Under Dynamic Conditions
Hard Material Modulation for (Skeletal) Tissue Engineering Purposes
Peeking into a Hidden Syndicate: Mitochondria of the Human Amniotic Membrane
Molecular Crowding – (in Cell Culture)
microRNA Modulation
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