Distance Corrections on Recombinant Sequences 1st Edition by David Bryant, Daniel Huson, Tobias Kloepper, Kay Nieselt Struwe- Ebook PDF Instant Download/Delivery. 9783540200765
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ISBN 13: 9783540200765
Author: David Bryant, Daniel Huson, Tobias Kloepper, Kay Nieselt Struwe
Sequences that have evolved under recombination have a ‘mosaic’ structure, with different portions of the alignment having evolved on different trees. In this paper we study the effect of mosaic sequence structure on pairwise distance estimates. If we apply standard distance corrections to sequences that evolved on more than one tree then we are, in effect, correcting according to an incorrect model. We derive tight bounds on the error introduced by this model mis-specification and discuss the ramifications for phylogenetic analysis in the presence of recombination.
Distance Corrections on Recombinant Sequences 1st Table of contents:
1 Introduction
2 Background
3 Correcting Distances Estimated from Mosaic Sequences
4 Experimental Results
5 Applications
6 Discussion – Error and the Phylogenetic Analysis of
Recombination
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