Diagnostic Pathology Transplant Pathology 2nd editon by Anthony Chang, Matthew Lindberg ISBN 0323553575 978-0323553575

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ISBN 10:  0323553575 
ISBN 13: 978-0323553575
Author: Anthony Chang, Matthew Lindberg 

Part of the highly regarded Diagnostic Pathology series, this updated volume by Drs. Anthony Chang and Robert B. Colvin is an ideal point-of-care reference to guide you through the complex realm of transplant pathology. Concise, focused chapters, supported by tables, diagrams, radiographs, and photographs, provide essential information to keep you up to date with the impact of new viral infections, updates from the Banff Allograft Conference, new information on next-generation sequencing, and much more.

• More than 20 experts present their collective knowledge to assist you with different aspects of transplant pathology, including rare issues such as the impact of new viral infections (e.g., the Zika virus on transplant patients who are immunosuppressed)
• Packed with high-quality images that provide examples and potential pitfalls of diagnostic lesions that you are likely to encounter
• Time-saving reference features include bulleted text, tables of diagnostic criteria, annotated images, and an extensive index
• Thoroughly updated content keeps you current with all aspects of transplant immunology and pathology, guiding you expertly through diagnostic challenges such as donor disease, surgical complications, allograft rejection, drug toxicity, opportunistic infections, and/or recurrent or de novo diseases that can occur simultaneously or at different times
• New Banff classifications are integrated into all chapters, covering pathology of all clinical organ transplants, including kidney, heart, lung, liver, pancreas, small bowel, and vascularized composite allografts as well as bone marrow allografts
• New coverage includes next-generation sequencing, which is quickly becoming the standard for HLA testing, as well as new drugs that are in clinical trials for the treatment of antibody-mediated rejection
• Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices

Diagnostic Pathology: Transplant Pathology 2nd Table of contents:

Part I: Introduction

1. Overview of Transplant Pathology
   • The Role of Transplant Pathology in Organ Transplantation
   • Challenges in Diagnosis of Transplant-Related Diseases
   • Immunology of Organ Transplantation: Basic Concepts
2. Immunological Mechanisms in Transplantation
   • Alloimmune Responses and Their Role in Rejection
   • T-cell and B-cell Mediated Responses
   • Role of Antibodies in Acute and Chronic Rejection
   • Mechanisms of Graft-versus-Host Disease (GVHD)

Part II: Pathology of Solid Organ Transplants

3. Kidney Transplantation
   • Acute Kidney Allograft Rejection
   • Chronic Kidney Allograft Dysfunction and Pathology
   • Infections and Post-transplant Lymphoproliferative Disorders in Kidney Transplantation
   • Pathological Changes in Diabetic Nephropathy and Other Complications
4. Liver Transplantation
   • Acute and Chronic Rejection in Liver Transplants
   • Liver Allograft Dysfunction and Its Causes
   • Infectious Complications and Their Pathological Features
   • Fibrosis and Cirrhosis in Liver Allografts
5. Heart Transplantation
   • Acute Cellular Rejection and Its Pathology
   • Chronic Allograft Vasculopathy in Heart Transplants
   • Infections and Other Complications in Heart Allografts
   • Pathology of Cardiac Allograft Vasculopathy
6. Lung Transplantation
   • Acute and Chronic Rejection in Lung Allografts
   • Obliterative Bronchiolitis and Its Pathology
   • Infections in Lung Transplants and Post-transplant Lymphoproliferative Disorders
   • Pathological Features in Acute Lung Injury
7. Pancreas and Islet Transplantation
   • Pathology of Pancreas Allografts
   • Acute and Chronic Rejection in Pancreatic and Islet Transplants
   • Islet Cell Dysfunction and Diabetes After Transplantation
8. Small Bowel and Multivisceral Transplants
   • Pathological Features of Small Bowel Allografts
   • Acute and Chronic Rejection in Small Bowel Transplants
   • Gastrointestinal Complications After Multivisceral Transplants

Part III: Special Topics in Transplant Pathology

9. Graft-Versus-Host Disease (GVHD)
   • Pathophysiology and Diagnosis of GVHD
   • Acute and Chronic GVHD in Solid Organ Transplants
   • Management and Clinical Implications of GVHD
10. Infections in Transplantation
    • Opportunistic Infections in Organ Transplant Recipients
    • Diagnosis and Pathology of Infections: Bacterial, Fungal, Viral
    • Viral Infections: Cytomegalovirus, Epstein-Barr Virus, and Others
    • Post-transplant Lymphoproliferative Disorders (PTLD)
11. Neoplasia in Transplant Recipients
    • Risk of Cancer After Organ Transplantation
    • Pathology of Post-transplant Neoplasms
    • Skin Cancers and Lymphomas in Transplant Recipients
    • Kaposi’s Sarcoma and Other Malignancies

Part IV: Diagnostic Techniques in Transplant Pathology

12. Histopathology of Transplanted Organs
    • Common Histopathological Patterns in Transplant Rejection
    • Grading and Staging of Rejection: Standard Criteria
    • Special Stains and Immunohistochemistry in Transplant Pathology
13. Molecular and Genetic Approaches in Transplantation
    • Molecular Diagnosis of Rejection and Graft Dysfunction
    • Gene Expression Profiling in Transplant Pathology
    • Role of Circulating Biomarkers in Diagnosis and Prognosis
14. Immunohistochemistry in Transplant Pathology
    • Key Immunohistochemical Markers in Transplant Pathology
    • Applications of Immunohistochemistry in Diagnosing Rejection and Infections

Part V: Management of Transplant-Related Pathology

15. Management of Acute and Chronic Rejection
    • Immunosuppressive Therapy and Its Impact on Pathology
    • Diagnosis and Treatment of Acute Cellular Rejection
    • Long-term Management of Chronic Rejection
16. Transplant Immunosuppression
    • Types of Immunosuppressive Drugs and Their Mechanisms
    • Toxicities of Immunosuppressive Therapy and Its Pathological Manifestations
    • Personalized Approaches to Immunosuppressive Therapy

Part VI: Case Studies and Clinical Applications

17. Case Studies in Transplant Pathology
    • Case-Based Discussion of Common and Rare Transplant Pathologies
    • Diagnostic Challenges and Management Strategies

Appendices

• Glossary of Transplant Pathology Terms
• Index

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