Diagnostic Pathology Kidney Diseases 2nd edition by Anthony Chang, Robert Colvin ISBN 0323377076 ‎ 978-0323377072

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ISBN 10: 0323377076 ‎ 
ISBN 13: ‎ 978-0323377072
Author: Anthony Chang, Robert Colvin 

Part of the highly regarded Diagnostic Pathology series, this updated volume is a visually stunning, easy-to-use reference covering all aspects of common and rare renal diseases and their variants. Outstanding images―including gross and microscopic pathology, a wide range of stains, and detailed medical illustrations―make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. Written by leading pathologists, this second edition presents an up-to-date, concise presentation of major pathological, clinical, pathophysiological, and genetic information for over 240 diagnoses.

Diagnostic Pathology: Kidney Diseases 2nd Table of contents:

Part I: Introduction to Kidney Diseases

1. Overview of Kidney Structure and Function
   • Anatomy and Physiology of the Kidneys
   • Renal Physiology: Filtration, Reabsorption, and Secretion
   • Basic Mechanisms of Renal Injury and Disease
2. Pathology of Kidney Diseases
   • Introduction to Renal Pathology
   • Mechanisms of Kidney Injury and Disease Progression
   • Classification of Kidney Diseases: Acute vs. Chronic

Part II: Acute Kidney Injury (AKI)

3. Etiology and Pathophysiology of AKI
   • Prerenal, Intrarenal, and Postrenal Causes
   • Cellular and Molecular Mechanisms of Acute Renal Injury
4. Morphology of Acute Kidney Injury
   • Histopathological Features of AKI
   • Tubular Necrosis and Acute Tubular Injury
   • Vascular and Glomerular Changes in AKI
5. Diagnostic Approaches in Acute Kidney Injury
   • Clinical and Laboratory Diagnosis of AKI
   • Imaging and Biomarkers in AKI
   • Differential Diagnosis and Staging of AKI

Part III: Chronic Kidney Disease (CKD)

6. Etiology and Pathophysiology of Chronic Kidney Disease
   • Causes of CKD: Diabetes, Hypertension, and Glomerulonephritis
   • Pathophysiological Mechanisms in CKD Progression
7. Histopathology of Chronic Kidney Disease
   • Glomerular, Tubular, and Interstitial Changes in CKD
   • Fibrosis and Scarring in the Kidney
   • Chronic Interstitial Nephritis and Vascular Changes
8. Diagnostic Criteria and Staging of CKD
   • Glomerular Filtration Rate (GFR) and Proteinuria as Markers
   • Staging Systems for CKD
   • Role of Biopsy in CKD Diagnosis

Part IV: Glomerular Diseases

9. Overview of Glomerular Pathology
   • Basic Glomerular Anatomy and Function
   • Common Mechanisms of Glomerular Injury
10. Primary Glomerulopathies
    • Minimal Change Disease
    • Focal Segmental Glomerulosclerosis (FSGS)
    • Membranous Nephropathy
    • IgA Nephropathy
11. Secondary Glomerulopathies
    • Glomerulonephritis in Systemic Diseases (SLE, Diabetes, Vasculitis)
    • Post-Infectious and Post-Streptococcal Glomerulonephritis
    • Hereditary Glomerulopathies (Alport Syndrome, etc.)
12. Diagnostic Evaluation of Glomerular Diseases
    • Urine Sediment Analysis
    • Biopsy Techniques and Histopathological Findings
    • Immunofluorescence and Electron Microscopy in Glomerulopathies

Part V: Tubulointerstitial Diseases

13. Overview of Tubulointerstitial Pathology
    • Structure and Function of the Renal Tubules and Interstitium
    • Mechanisms of Tubulointerstitial Injury
14. Acute Tubulointerstitial Nephritis
    • Causes of Acute Tubulointerstitial Nephritis (Drugs, Infection, etc.)
    • Histopathological Features of Acute Tubulointerstitial Nephritis
15. Chronic Tubulointerstitial Diseases
    • Chronic Interstitial Nephritis
    • Drug-Induced Tubulointerstitial Disease
    • Renal Tubular Dysfunction and Fanconi Syndrome

Part VI: Vascular Renal Diseases

16. Vascular Pathology of the Kidney
    • Overview of Renal Blood Vessels and Their Role in Kidney Function
    • Hypertensive Nephropathy
17. Renal Artery Stenosis and Atherosclerotic Disease
    • Pathophysiology and Diagnosis of Renal Artery Stenosis
    • Impact on Kidney Function and Blood Pressure Regulation
18. Vasculitis and Kidney Disease
    • Small Vessel Vasculitis (e.g., ANCA-Associated Vasculitis)
    • Large Vessel Vasculitis (e.g., Takayasu’s Arteritis)
    • Diagnostic Features of Renal Involvement in Vasculitis

Part VII: Cystic Kidney Diseases

19. Polycystic Kidney Disease (PKD)
    • Genetics and Pathophysiology of PKD
    • Diagnostic Imaging and Biopsy Findings
    • Complications and Disease Progression
20. Acquired Cystic Kidney Disease
    • Causes and Pathophysiology of Acquired Cystic Disease
    • Diagnosis and Clinical Implications
    • Renal Cell Carcinoma in Cystic Kidney Disease

Part VIII: Neoplasms of the Kidney

21. Benign Renal Tumors
    • Renal Hemangioma, Oncocytoma, and Angiomyolipoma
    • Histopathological Features and Diagnosis
22. Renal Cell Carcinoma (RCC)
    • Subtypes of Renal Cell Carcinoma: Clear Cell, Papillary, and Chromophobe
    • Molecular Pathogenesis of RCC
    • Diagnostic Workup and Staging of RCC
23. Other Renal Neoplasms
    • Urothelial Carcinoma of the Renal Pelvis
    • Wilms Tumor and Other Pediatric Renal Tumors
    • Rare Renal Tumors (e.g., Renal Sarcoma, Metastases)

Part IX: Diagnostic Techniques in Renal Pathology

24. Renal Biopsy Techniques
    • Indications for Renal Biopsy
    • Technique and Procedure of Renal Biopsy
    • Complications and Interpretation of Renal Biopsy Results
25. Immunohistochemistry and Molecular Pathology in Kidney Diseases
    • Immunohistochemical Markers in Renal Disease Diagnosis
    • Molecular Testing and Genetic Profiling in Renal Pathology
    • Role of Next-Generation Sequencing in Renal Diseases
26. Imaging in Kidney Disease
    • Role of Ultrasound, CT, and MRI in Renal Diagnosis
    • Imaging Techniques for Renal Cysts and Tumors
    • Functional Imaging: Renal Scintigraphy and PET

Part X: Treatment and Management of Kidney Diseases

27. General Approaches to the Management of Kidney Disease
    • Conservative and Supportive Management
    • Dialysis and Renal Replacement Therapy
    • Transplantation in Chronic Kidney Disease
28. Pharmacological Treatment of Kidney Diseases
    • Pharmacotherapy for Glomerular Diseases
    • Management of Hypertension and Diabetes in Renal Disease
    • Immunosuppressive Therapy for Renal Vasculitis and Glomerulonephritis
29. Renal Transplantation
    • Indications for Renal Transplantation
    • Pre- and Post-Transplantation Pathology

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