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Diagnostic Pathology Breast 2nd edition by Susan Lester, David Hicks ISBN 0323377122 978-0323377126

Name: Diagnostic Pathology Breast 2nd edition by Susan Lester, David Hicks ISBN 0323377122 978-0323377126
SKU: EB-3778
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Authors:David G. Hicks MD , Series:Pathology [239] , Author sort:Hicks, David G. MD , Ids:9780323377126 , Languages:Languages:eng , Published:Published:Mar 2016 , Publisher:Amirsys Elsevier

SKU: EB-3778 Category: eBook PDF Tags: David Hicks, Diagnostic Pathology, Susan Lester

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Diagnostic Pathology: Breast 2nd edition by Susan Lester, David Hicks – Ebook PDF Instant Download/Delivery. 0323377122 978-0323377126
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ISBN 10: 0323377122
ISBN 13: 978-0323377126
Author: Susan Lester, David Hicks

Part of the highly regarded Diagnostic Pathology series, Diagnostic Pathology: Breast,second edition, is a visually stunning, easy-to-use reference covering all aspects of breast pathology. Outstanding images, including gross and microscopic pathology, a wide range of supportive immunohistochemistry, and detailed medical illustrations with numerous examples of morphologic findings, make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. This second edition incorporates the most recent clinical, pathological, histological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice.

Thoroughly updated content throughout, including coverage of new technologies and molecular approaches that are quickly moving out of the laboratory into clinical diagnosis and therapeutic decision making
New to this edition: Tips on how to biopsy and send the best block for breast cancer predictive factor testing, updated prognostic assays, updated national guidelines (including HER2 testing) with photos, neoadjuvant treatment, new drugs for HER2-positive cancers, and pattern-based differential diagnosis chapters and guidance on the most helpful IHC antibodies
For each anatomical site, you will find CAP cancer staging and specimen handling protocols, plus detailed immunohistochemistry panels to accompany the images
High-quality, carefully annotated color images provide clinically and diagnostically important information
Fully integrated, searchable, and linked content between differential diagnostic categories is perfectly suited for residents, while new images and outstanding graphics make this text ideal for both residents and practitioners
Time-saving reference features include bulleted text, a variety of data tables, key facts in each chapter, annotated images, and an extensive index
Expert Consult eBook version included,whichallows you to search all of the text, figures, and references from the book on a variety of devices

Diagnostic Pathology: Breast 2nd Table of contents:

Part I: General Principles of Breast Pathology

Introduction to Breast Pathology
- Normal Breast Anatomy and Physiology
- Histology of the Breast
- Clinical Evaluation of Breast Disease
- Role of Imaging in Breast Pathology
Breast Biopsy Techniques
- Types of Breast Biopsy: Core Needle, Fine Needle Aspiration, and Excisional Biopsy
- Indications and Contraindications for Biopsy
- Processing and Handling of Breast Tissue Specimens
Histopathological Examination of the Breast
- Basic Histopathological Techniques and Stains
- Key Morphological Features in Breast Pathology
- Diagnostic Challenges in Breast Pathology

Part II: Benign Breast Lesions

Non-Proliferative Lesions
- Fibrocystic Changes
- Simple Cysts
- Apocrine Metaplasia
- Fat Necrosis and Its Mimics
Proliferative Lesions Without Atypia
- Epithelial Hyperplasia
- Sclerosing Adenosis
- Complex Sclerosing Lesion
- Radial Scars and Their Clinical Significance
Proliferative Lesions With Atypia
- Atypical Ductal Hyperplasia (ADH)
- Atypical Lobular Hyperplasia (ALH)
- Differential Diagnosis and Management
Fibroadenoma and Related Lesions
- Fibroadenoma: Pathogenesis, Subtypes, and Diagnosis
- Phyllodes Tumors: Classification and Management
- Fibroadenomatoid Hyperplasia and Its Mimics

Part III: Malignant Breast Lesions

Invasive Ductal Carcinoma (IDC)
- Subtypes of IDC: Luminal, HER2+, Triple-Negative
- Histopathology of IDC
- Prognostic Features: Grading and Staging
Invasive Lobular Carcinoma (ILC)
- Histopathology of ILC
- Diagnosis and Differential Diagnosis
- Molecular Features and Prognosis
Ductal Carcinoma In Situ (DCIS)
- Classification and Subtypes of DCIS
- Histopathological Features of DCIS
- Management and Risk of Invasive Disease
Lobular Carcinoma In Situ (LCIS)
- Pathogenesis and Diagnosis
- Role of LCIS as a Marker for Increased Risk
- Management and Follow-Up Guidelines
Other Invasive Carcinomas
- Inflammatory Breast Cancer
- Medullary Carcinoma
- Mucinous Carcinoma and Colloid Carcinoma
- Tubular Carcinoma and Cribriform Carcinoma

Part IV: Prognostic and Predictive Factors in Breast Cancer

Hormone Receptor Status
- Estrogen Receptor (ER) and Progesterone Receptor (PR) Testing
- Clinical Implications of Hormone Receptor Status
- Impact of Hormone Receptor Status on Treatment and Prognosis
HER2/neu Status
- Testing for HER2 Overexpression
- Role of HER2 in Breast Cancer Prognosis and Treatment
- Targeted Therapies: Trastuzumab and Other HER2-targeted Agents
Genomic and Molecular Markers
- Oncotype DX and Other Genomic Assays
- Role of Molecular Subtyping in Prognosis
- Future Directions in Molecular Pathology of Breast Cancer

Part V: Metastatic Breast Cancer

Patterns of Breast Cancer Spread
- Lymphatic Spread: Axillary Lymph Node Metastasis
- Hematogenous Spread: Bone, Liver, Lung, and Brain Metastases
- Clinical and Histopathological Features of Metastatic Disease
Diagnostic Approaches in Metastatic Breast Cancer
- Immunohistochemical Markers in Metastatic Carcinoma
- Differentiating Primary and Metastatic Breast Carcinoma
- Molecular Techniques for Diagnosis and Prognosis

Part VI: Special Considerations in Breast Pathology

Breast Pathology in the Male Breast
- Gynecomastia: Pathology and Diagnosis
- Male Breast Cancer: Epidemiology, Risk Factors, and Prognosis
Pathology of the Breast in Pregnancy and Lactation
- Changes in the Breast During Pregnancy
- Lactational Changes and Pathological Mimics
- Breast Cancer Diagnosis During Pregnancy and Lactation
Breast Cancer in Special Populations
- Young Women and Breast Cancer
- Genetic Syndromes: BRCA1, BRCA2, and Other Mutations
- Familial and Hereditary Breast Cancer

Part VII: Advances in Breast Cancer Pathology

Molecular Pathology and Breast Cancer
- Genetic Mutations in Breast Cancer
- Role of Next-Generation Sequencing (NGS) in Breast Cancer Diagnosis
- Advances in Liquid Biopsy and Biomarker Discovery
Pathology of Precursor Lesions
- Atypical Ductal Hyperplasia and Its Role in Breast Cancer Risk
- Lobular Neoplasia and Its Implications for Screening and Surveillance
Breast Cancer Screening and Pathology
- Role of Pathology in Breast Cancer Screening Programs
- Mammography, Ultrasound, and MRI: Integration with Pathological Findings
- Management of Screen-Detected Lesions and Biopsy Techniques

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