Dales pharmacology condensed E book 3rd Edition by Clive Page, Simon Pitchford 0702078182 9780702078187

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ISBN 10: 0702078182

ISBN 13: 9780702078187

Author: Clive P. Page; Simon Pitchford

Covering the essential basic science and principles of pharmacology using concise text and diagrams, Dale’s Pharmacology Condensed, 3rd Edition, presents the key facts and concepts that are key to understanding how drugs work and their underlying pathophysiological processes. Each chapter provides an organized, consistent approach to efficient learning and retention of complex information. This concise text is an ideal companion volume to Rang and Dale’s Pharmacology, as well as a stand-alone condensed textbook or review book for exams.

Dales pharmacology condensed E book 3rd Table of contents:

1. Preface

2. Pharmacology, drug names and classification systems

Drug Names

Receptors, ion channels and enzymes

3. General principles of drug action

Receptors as Drug Targets

Antagonists

Allosteric Modulation

Desensitization and Tolerance

4. Molecular aspects of drug action

Receptors as Targets for Drug Action

Carrier Molecules as Targets for Drug Action

Ion Channels as Targets for Drug Action

Enzymes as Targets for Drug Action

5. Pharmacokinetic and other factors influencing drug action

Absorption and Distribution of Drugs

Drug Metabolism and Excretion

Measurement of Pharmacokinetics

6. Pharmacodynamics and the measurement of drug action

Principles of Bioassay

New Drug Development

Clinical Trials

7. Drug discovery and the development of small molecules

The Drug Discovery Phase

The Preclinical Development Phase

The Clinical Development Period

8. Drug discovery and the development of biologicals

Proteins and Polypeptides and Gene Therapy

Antibodies

Considerations During Antibody Characterization Phase

Safety Aspects During Preclinical Development

9. Drug safety, toxicology and pharmacovigilance

Safety Pharmacology

Toxicology

Biologicals

Pharmacovigilance

10. Regulation of drug use

Drug Regulation for New Drugs

Drug Information to Public

Drug Regulations Relating to Access to Drugs

11. Outline of transmission and drug action in the nervous system

Central Nervous System

Autonomic Nervous System

Neurotransmitters and Co-Transmitters

Cholinergic Transmission

Synthesis, Storage and Release of Acetylcholine and Summary of Drug Action

Nicotinic Receptors

Muscarinic Receptors

Cholinesterases and Anticholinesterases

Adrenergic Transmission

Transmission at the Noradrenergic Varicosity with Summary of Drug Action

The Action of Drugs on Adrenoceptors

12. Drugs and neurological disorders

Neurodegenerative Disorders

Stroke

Parkinson’s Disease

Alzheimer’s Disease

Other Neurodegenerative Diseases

Anxiety and Hypnosis

Psychosis

Affective Disorders

Epilepsy

13. Drugs and pain

Analgesia (The Relief of Pain)

Opioid Analgesics

Paracetamol and Nsaids

Treatment of Neuropathic Pain

Other Pain-Relieving Drugs

14. Drugs and the cardiovascular system

Cardiac Rhythm and Dysrhythmias

Blood Pressure Control and Hypertension

Cardiac Blood Flow, Angina and Myocardial Infarction

Angina

Myocardial Infarction

15. Drugs and blood: haematopoiesis and haemostasis

The Haematopoietic System

Haemostasis and Thrombosis

16. Drugs and the inflammatory and immune response

Mediators of Inflammation and the Drugs Affecting Them

Nonsteroidal Anti-Inflammatory Drugs

Glucocorticoids

Drugs Used for Gout

Drugs Used to Modulate Immune Responses

17. Drugs and the endocrine and metabolic systems

The Hypothalamic-Pituitary Axis

The Adrenal Cortex

The Thyroid

The Pancreas, Blood Sugar and Diabetes

Drugs Used to Treat Diabetes

The Reproductive System

The Female Reproductive System

The Male Reproductive System

18. Drugs and the renal system

Drugs Acting on the Kidney

19. Drugs and the pulmonary system

Asthma

Chronic Obstructive Pulmonary Disease

Cough

20. Drugs and the musculoskeletal system

Bone metabolism

21. Drugs and the gastrointestinal tract

Gastric Secretion and Peptic Ulcer

Emesis and Anti-Emetic Drugs

Other Gastrointestinal Conditions

22. Drugs and the genitourinary system

Benign prostatic hyperplasia

Urinary Incontinence

Erectile dysfunction

23. Drugs and the skin

Dermatitis (eczema)

Acne

Psoriasis

Treatment of skin disorders

24. Drugs and the eye

Glaucoma

25. Drugs and the ear

Physiology of the ear

Diseases of the ear

26. Drugs used in anaesthesia

Local anaesthetics

General anaesthetics

27. Drug use in disorders of nutrition

Obesity

Eating Disorders

28. Drug use in dentistry

Physiology of the oral cavity

The teeth and other oral tissues

Oral mucosa

Salivary glands

Diseases of the oral cavity

Systemic factors may also play a role in gingivitis

Common diseases of the oral mucosa

29. Antiviral drugs

30. Antibacterial drugs

31. Antifungal drugs

Antifungal Drugs

32. Drugs and parasites: Anti-protozoal and anti-helminthic drugs

Malaria

Other Protozoal Infections

33. Drugs and cancer

Pathology

Anticancer drugs

34. Prescribing and personalizing drug treatments

Age, gender and origin

Drug interactions

Effect of disease on drug action

Genetic variation

Personalized medicines

35. Venoms, toxins, poisons and herbs

Toxicity and target organ damage

Medical procedures for treatment of poisoning and toxicity

Natural sources

Industrial or man-made toxins

Carcinogensis and Mutagenesis

Herbal Medicines

36. Drug dependence and drug abuse

Pathophysiology

Psychomotor Stimulants

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