Cancer Epidemiology Volume 1 Host Susceptibility Factors 2009th Edition by Mukesh Verma ISBN 1588299871 978-1588299871

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ISBN 10:       1588299871
ISBN 13: 978-1588299871
Author:         Mukesh Verma

Population studies and epidemiology facilitate the discovery of genetic and environmental determinants of cancer and the development of new approaches to cancer control and prevention, therefore they play a central role in the creation of health policies. Cancer Epidemiology compiles areas of research which cover etiological factors or determinants that contribute to the development of cancer and describe the latest technologies in cancer epidemiology. In Volume 1, Host Susceptibility Factors, leading experts provide chapters on cancer incidence, prevalence, mortality and surveillance, methods, technologies and study design in cancer epidemiology as well as host susceptibility factors in cancer epidemiology. Although a non-standard volume of the highly successful Methods in Molecular Biology™ series, this comprehensive text retains the commitment of the series to collecting the kind of detailed, up-to-date information and implementation advice that is crucial for getting optimal results.

Cutting-edge and essential, Cancer Epidemiology allows readers to get the maximum advantage of the methods involved in this exciting and important field.

Cancer Epidemiology Volume 1, Host Susceptibility Factors 2009th Table of contents:

Section 1: Introduction to Cancer Epidemiology

1. Chapter 1: Overview of Cancer Epidemiology
   • Definition and Scope
   • Historical Background and Advances
   • Principles and Methodologies in Cancer Epidemiology
   • Global Cancer Burden and Trends

Section 2: Genetic Factors in Cancer Susceptibility

2. Chapter 2: Genetic Susceptibility to Cancer

   • Hereditary Cancer Syndromes
   • Role of Oncogenes and Tumor Suppressor Genes
   • Genetic Polymorphisms and Cancer Risk
   • Advances in Cancer Genomics

3. Chapter 3: Genetic and Environmental Interactions

   • Gene-Environment Interactions in Cancer
   • Epigenetic Mechanisms in Cancer Susceptibility
   • Methylation, Histone Modification, and Cancer Risk
   • Impact of Inherited Variability in Environmental Responses

Section 3: Immune System and Cancer Susceptibility

4. Chapter 4: Immunology and Cancer Susceptibility

   • Role of the Immune System in Cancer Development
   • Immune Surveillance and Tumor Escape Mechanisms
   • Inflammatory Responses and Cancer Susceptibility
   • Autoimmune Diseases and Cancer Risk

5. Chapter 5: Infections and Cancer

   • Infectious Agents and Cancer: Overview
   • Human Papillomavirus (HPV) and Cervical Cancer
   • Hepatitis B and C Viruses in Liver Cancer
   • Epstein-Barr Virus and Lymphomas
   • Other Infectious Agents in Cancer Pathogenesis

Section 4: Hormonal and Reproductive Factors

6. Chapter 6: Hormonal Factors and Cancer Susceptibility

   • Hormones and Cancer Risk: Mechanisms
   • Estrogen and Breast Cancer
   • Prostate Cancer and Androgen Regulation
   • Thyroid Hormones and Cancer Development

7. Chapter 7: Reproductive Factors and Cancer Risk

   • Pregnancy, Parity, and Breast Cancer Risk
   • Oral Contraceptives and Cancer Risk
   • Menopause and Hormonal Changes in Cancer Susceptibility
   • Reproductive Health and Ovarian Cancer Risk

Section 5: Lifestyle Factors and Environmental Exposures

8. Chapter 8: Diet and Cancer Susceptibility

   • Diet, Nutrition, and Cancer Risk
   • Obesity and Cancer Development
   • Specific Dietary Factors in Cancer Prevention
   • The Role of Antioxidants and Phytochemicals in Cancer

9. Chapter 9: Tobacco Use and Cancer Susceptibility

   • Tobacco and Cancer Risk: An Overview
   • Mechanisms of Tobacco-Induced Cancer
   • Smoking and Lung Cancer
   • Other Smoking-Related Cancers: Bladder, Head, and Neck

10. Chapter 10: Occupational and Environmental Exposures

• Occupational Carcinogens and Cancer Risk
• Pesticides, Heavy Metals, and Other Exposures
• Air Pollution and Cancer
• Occupational Exposures in Specific Populations

Section 6: Aging and Cancer

11. Chapter 11: Aging and Cancer Susceptibility

• The Biology of Aging and Cancer Risk
• Age-Related Changes in DNA Repair Mechanisms
• Age as a Risk Factor for Specific Cancer Types
• Impact of Aging on Cancer Treatment and Survival

Section 7: Emerging Areas of Research

12. Chapter 12: Epigenetics and Cancer

• DNA Methylation and Histone Modification in Cancer
• Epigenetic Biomarkers for Cancer Susceptibility
• Environmental Influences on Epigenetic Changes
• Epigenetics as a Tool for Cancer Prevention and Treatment

13. Chapter 13: Microbiome and Cancer Susceptibility

• The Role of Gut Microbiota in Cancer Development
• Microbial Imbalance and Cancer Risk
• Impact of Antibiotics, Probiotics, and Diet on Cancer

Section 8: Conclusion

14. Chapter 14: Conclusion and Future Directions

• Advances in Host Susceptibility Research
• Integration of Genetic, Environmental, and Lifestyle Factors
• New Approaches in Cancer Prevention and Early Detection
• Future Challenges and Research Opportunities in Cancer Epidemiology

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