Breast Pathology 1st edition by Anna Sapino, Janina Kulka ISBN 3319625381 978-3319625386

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ISBN 10: 3319625381
ISBN 13:  978-3319625386
Author: Anna Sapino, Janina Kulka 

This book covers the complete field of breast pathology – from Acinic cell carcinoma to Usual Epithelial Hyperplasia. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.

Breast Pathology 1st Table of contents:

Part I: Introduction to Breast Pathology

1. Introduction to Breast Pathology
   • The Role of Pathology in Breast Disease Diagnosis
   • Overview of Breast Anatomy and Physiology
   • Historical Development of Breast Pathology
2. Basic Principles of Breast Pathology
   • Classification of Breast Diseases
   • Mechanisms of Carcinogenesis in the Breast
   • Pathological Features and Diagnosis

Part II: Benign Breast Diseases

3. Non-neoplastic Lesions of the Breast
   • Benign Breast Diseases: Fibrocystic Changes, Fibroadenomas, and Others
   • Breast Infections: Mastitis and Abscesses
   • Breast Cysts: Simple, Complex, and Infection-related
4. Proliferative Lesions Without Atypia
   • Usual Ductal Hyperplasia and its Significance
   • Sclerosing Adenosis and Other Proliferative Lesions
5. Atypical Hyperplasias
   • Atypical Ductal Hyperplasia (ADH)
   • Atypical Lobular Hyperplasia (ALH)
   • Diagnostic Challenges and Clinical Significance

Part III: Malignant Breast Disease

6. Breast Cancer: General Pathology
   • Pathogenesis of Breast Cancer
   • Epidemiology and Risk Factors
   • Molecular Biology and Genetic Alterations in Breast Cancer
   • Grading and Staging of Breast Cancer
7. Invasive Carcinoma
   • Invasive Ductal Carcinoma (IDC)
   • Invasive Lobular Carcinoma (ILC)
   • Medullary, Mucinous, and Other Special Types of Invasive Carcinomas
8. Non-invasive Carcinomas (In Situ)
   • Ductal Carcinoma in Situ (DCIS)
   • Lobular Carcinoma in Situ (LCIS)
   • Pathological Features and Management
9. Inflammatory Breast Cancer
   • Clinical Presentation and Pathological Features
   • Prognosis and Treatment Challenges
10. Breast Cancer Molecular Subtypes
    • Estrogen Receptor (ER) and Progesterone Receptor (PR) Expression
    • HER2 Overexpression and Its Clinical Implications
    • Triple-Negative Breast Cancer
    • Molecular Profiling and Precision Medicine in Breast Cancer

Part IV: Pathology of Metastatic and Other Malignant Lesions

11. Metastatic Lesions to the Breast
    • Common Primary Sites and Pathological Features of Metastasis
    • Diagnosis and Differentiation from Primary Breast Cancer
12. Rare Malignant Lesions of the Breast
    • Angiosarcoma, Lymphoma, and Other Rare Malignant Tumors
    • Tumors Arising in the Male Breast

Part V: Diagnostic Approaches and Techniques

13. Histopathology and Cytopathology of the Breast
    • Role of Core Needle Biopsy and Fine Needle Aspiration (FNA)
    • Histological Features in Benign and Malignant Lesions
    • Cytological Features and Diagnosis
14. Immunohistochemistry in Breast Pathology
    • Role of Immunohistochemistry in Diagnosis and Prognosis
    • Common Markers in Breast Cancer: ER, PR, HER2, Ki-67, and Others
    • Molecular Testing: Gene Expression Profiling, FISH, and PCR
15. Imaging in Breast Pathology
    • Mammography, Ultrasound, and MRI in Breast Disease
    • Radiological-Pathological Correlation
    • Role of Digital Pathology and Imaging in Breast Cancer Diagnosis

Part VI: Breast Pathology in Special Populations

16. Breast Pathology in Pregnancy and Lactation
    • Pregnancy-Related Changes in the Breast
    • Benign and Malignant Lesions During Pregnancy and Lactation
    • Challenges in Diagnosis and Treatment
17. Breast Pathology in the Elderly
    • Age-Related Changes in Breast Tissue
    • Incidence and Pathology of Breast Cancer in Older Women
    • Challenges in Management of Elderly Patients with Breast Cancer

Part VII: Prognosis and Management

18. Prognostic Factors in Breast Cancer
    • Tumor Size, Lymph Node Involvement, and Margins
    • Molecular Prognostic Markers and Their Role in Treatment
    • The Role of Oncoproteins and Tumor Suppressors in Prognostication
19. Breast Cancer Treatment and Pathology
    • Surgical Pathology in Breast Cancer: Mastectomy and Lumpectomy Specimens
    • Chemotherapy, Radiotherapy, and Hormonal Therapy
    • Targeted Therapy and Immunotherapy in Breast Cancer
    • Post-Treatment Pathology: Monitoring for Recurrence

Part VIII: Future Directions in Breast Pathology

20. Emerging Concepts and Technologies in Breast Pathology
    • Advances in Molecular Pathology and Genomic Testing
    • Personalized Medicine and Targeted Therapies
    • Role of Artificial Intelligence and Digital Pathology in Breast Cancer Diagnosis
    • Future Trends in Screening and Early Detection

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