Breast Disease Diagnosis and Pathology 1st editon by Adnan Aydiner, Abdullah Ä°ÄŸci, Atilla Soran ISBN 3319228420 978-3319228426

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ISBN 10: 3319228420 
ISBN 13: 978-3319228426
Author:  Adnan Aydiner, Abdullah İğci, Atilla Soran 

This first of two volumes provides and in-depth account of breast disease characteristics, imaging and diagnosis. Covering from breast anatomy and tumor biology to benign and malignant lesions this is an indispensable companion for breast specialists, medical oncologists, radiologists and pathologists. The book is organised in themed parts exploring topics such as epidemiology, risk factors, genetic biomarkers, pathological evaluation of tumors and biopsy techniques.

With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain an interdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into pathological and epidemiological aspects of breast disease. Covering both theoretical and practical aspects of breast cancer this is a highly informative and carefully presented book which will appeal to an international audience of breast cancer practitioners.

Breast Disease Diagnosis and Pathology 1st  Table of contents:

Section I: Introduction to Breast Disease

1. Introduction to Breast Pathology
   • Overview of Breast Anatomy and Physiology
   • The Role of Breast Pathology in Diagnosis and Treatment
   • The Evolution of Breast Disease Diagnosis
2. Basic Principles in Breast Disease Diagnosis
   • Clinical Evaluation of the Breast
   • Imaging Techniques in Breast Disease Diagnosis: Mammography, Ultrasound, MRI
   • Core Needle Biopsy and Fine Needle Aspiration

Section II: Benign Breast Conditions

3. Non-Proliferative Lesions
   • Fibrocystic Changes
   • Simple Cysts and Ductal Ectasia
   • Other Non-Proliferative Conditions
4. Proliferative Lesions Without Atypia
   • Sclerosing Adenosis
   • Radial Scars
   • Complex Sclerosing Lesions
5. Atypical Ductal and Lobular Hyperplasia
   • Atypical Ductal Hyperplasia (ADH)
   • Atypical Lobular Hyperplasia (ALH)
   • Risk Factors and Management
6. Fibroadenomas
   • Pathologic Features and Subtypes
   • Management and Clinical Implications
7. Benign Phyllodes Tumors
   • Pathology and Diagnosis of Phyllodes Tumors
   • Classification and Treatment Options
8. Breast Infections and Inflammatory Conditions
   • Acute and Chronic Mastitis
   • Granulomatous Mastitis
   • Periductal Mastitis and Duct Ectasia

Section III: Malignant Breast Disease

9. Invasive Carcinomas
   • Invasive Ductal Carcinoma (IDC)
   • Invasive Lobular Carcinoma (ILC)
   • Other Invasive Carcinomas and Their Subtypes
10. Ductal Carcinoma In Situ (DCIS)
    • Pathologic Features and Subtypes of DCIS
    • Diagnosis, Staging, and Treatment Approaches
11. Special Types of Breast Cancer
    • Medullary Carcinoma
    • Mucinous Carcinoma
    • Tubular Carcinoma
    • Inflammatory Breast Cancer
12. Triple-Negative Breast Cancer
    • Clinical and Pathological Features
    • Molecular Characteristics and Prognostic Implications
13. HER2-Positive Breast Cancer
    • Pathology and Molecular Diagnosis
    • Targeted Therapies for HER2-Positive Breast Cancer
14. Hormone Receptor-Positive Breast Cancer
    • Estrogen and Progesterone Receptor Expression
    • Pathologic Features and Prognostic Significance

Section IV: Lymphatic and Vascular Involvement

15. Lymph Node Involvement in Breast Cancer
    • Sentinel Lymph Node Biopsy
    • Pathology of Lymph Node Metastasis
    • Management of Lymphatic Involvement
16. Vascular Invasion in Breast Cancer
    • Pathologic Features of Vascular Invasion
    • Impact on Prognosis and Treatment

Section V: Pathology of Metastatic Disease

17. Metastatic Spread of Breast Cancer
    • Patterns of Metastasis
    • Common Sites of Distant Metastasis
    • Pathology of Metastatic Breast Cancer

Section VI: Molecular and Genetic Aspects

18. Genetic and Molecular Pathology of Breast Cancer
    • Hereditary Breast Cancer: BRCA1 and BRCA2
    • Other Genetic Mutations (e.g., TP53, PTEN)
    • Molecular Subtypes of Breast Cancer and Their Significance
19. Biomarkers in Breast Cancer
    • Role of Tumor Markers in Diagnosis and Prognosis
    • Molecular Tests for Personalized Treatment
20. Pathology of Metastatic Breast Cancer
    • Diagnosis of Metastatic Breast Disease
    • Role of Pathology in Treatment Decisions

Section VII: Management and Therapeutics

21. Surgical Pathology in Breast Disease
    • Surgical Management of Benign and Malignant Lesions
    • Pathologic Evaluation of Surgical Margins and Lymph Nodes
22. Chemotherapy, Hormonal Therapy, and Targeted Therapy
    • Role of Pathology in Guiding Therapy Decisions
    • Histopathologic Features Indicative of Treatment Response
23. Radiation Therapy and Its Pathologic Effects
    • Radiation-Induced Changes in Breast Tissue
    • Managing Post-Treatment Changes in Breast Pathology

Section VIII: Advances in Breast Disease Pathology

24. Advances in Breast Disease Diagnosis
    • New Technologies in Imaging and Biopsy Techniques
    • Advances in Molecular Pathology and Next-Generation Sequencing
25. Challenges and Controversies in Breast Pathology
    • Controversies in Diagnosis and Classification
    • Challenges in Identifying New and Rare Breast Disease Types
    • Pathology’s Role in Overdiagnosis and Overtreatment

Appendices

• Glossary of Terms
• Index

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