Blood Science Principles and Pathology 2nd Edition by Andrew Blann, Nessar Ahmed ISBN 1119864119 978-1119864110

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ISBN 10: 1119864119
ISBN 13:  978-1119864110
Author:  Andrew Blann, Nessar Ahmed

Blood Science

The second edition of the leading introduction to blood science, with updated new illustrations and case studies

Blood Science: Principles and Pathology integrates hematology and blood transfusion, ­clinical biochemistry, and immunology to provide a thorough introduction to this rapidly expanding discipline. Reflecting recent changes in education and training for healthcare scientists, this comprehensive textbook covers the analytical techniques used in blood ­science, the diagnosis and management of various blood disorders, and more.

Fully revised, the second edition presents new case studies and high-quality images ­throughout, illustrating the practical skills and knowledge required by today’s under­graduate students and practitioners. Detailed yet accessible chapters contain learning objectives and summaries, links to further readings and resources, and real-world case studies with easy-to-follow interpretations. Throughout the text, the authors highlight how laboratory data and clinical details are used to investigate patients with actual or suspected diseases in real-world scenarios:

• Multi-disciplinary view merging biochemical, hematological, immunological, and genetical knowledge into a single discipline: Blood science
• Discusses advances in molecular genetics identifying mutations resulting in the occurrence of certain pathological conditions such as leukaemia
• Presents an expanded concluding chapter with detailed case reports that integrate biochemistry, immunology, and haematology, which all contribute to the investigation of respective conditions
• Explains the potentials for developing tests such as non-coding RNAs
• Offers further reading suggestions to dive even deeper into discussed subjects and concepts

Designed to meet the needs of undergraduate students taking blood science modules in biomedical, biological, and healthcare science programs, Blood Science: Principles and Pathology, Second Edition is also an invaluable guide for new graduates entering the field, as well as those training for professional qualifications or working with blood samples in laboratory-based environments.

Blood Science Principles and Pathology 2nd Table of contents:

• Introduction to Hematology and Blood Science

  • Overview of hematology as a medical specialty.
  • Blood composition and functions.
  • The importance of understanding blood in clinical diagnosis and treatment.

• Hematopoiesis

  • The process of blood cell formation in the bone marrow.
  • Regulation of hematopoiesis and the role of stem cells.
  • Disorders of hematopoiesis.

• Blood Cells and Their Functions

  • Red blood cells (RBCs), white blood cells (WBCs), and platelets: structure, function, and lifespan.
  • Disorders of red blood cells (e.g., anemia, polycythemia).
  • Disorders of white blood cells (e.g., leukopenia, leukemia, lymphoma).
  • Platelet disorders (e.g., thrombocytopenia, thrombocytosis).

• Hemostasis and Coagulation

  • The coagulation cascade and its components.
  • Disorders of coagulation (e.g., hemophilia, vitamin K deficiency, clotting factor deficiencies).
  • Platelet function and bleeding disorders.

• Anemia and Red Blood Cell Disorders

  • Causes of anemia: nutritional deficiencies, blood loss, bone marrow disorders, and hemolytic diseases.
  • Diagnostic approaches to anemia.
  • Inherited and acquired disorders of red blood cells (e.g., sickle cell disease, thalassemia).

• Leukemia and Lymphoma

  • Overview of hematologic malignancies.
  • Classification of leukemia and lymphoma.
  • Pathophysiology, diagnosis, and treatment of blood cancers.

• Disorders of Hemostasis

  • Thrombosis and embolism.
  • Hemorrhagic disorders and their causes.
  • Diagnostic and therapeutic approaches to clotting and bleeding disorders.

• Infectious Diseases and Hematologic Implications

  • How infections affect the blood and bone marrow.
  • Blood infections and parasitic infestations (e.g., malaria).
  • Immune response to infection in the blood.

• Blood Transfusion Medicine

  • Blood collection, storage, and transfusion processes.
  • Blood typing, cross-matching, and transfusion reactions.
  • Complications of blood transfusion and their management.

• Molecular and Genetic Aspects of Hematology

  • Genetic diseases affecting the blood (e.g., hemophilia, sickle cell).
  • Advances in molecular diagnostics in hematology.
  • Gene therapy and its role in blood disorders.

• Pathology of Bone Marrow

  • Bone marrow examination and its diagnostic significance.
  • Diseases of the bone marrow, including myelodysplastic syndromes and myelofibrosis.

• Clinical Pathology in Hematology

  • Laboratory tests in hematology: complete blood count (CBC), bone marrow biopsy, coagulation tests.
  • Approaches to diagnosing hematological conditions in clinical practice.

• Emerging Trends and Future Directions in Hematology

  • Advances in technology and treatment modalities.
  • New therapies and clinical trials in blood science.
  • Future research directions in hematology and pathology.

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