BIOS Instant Notes in Biochemistry 4th Edition by David Hames ISBN 0415608459 9780415608459

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Product details:

ISBN 10:       0415608459
ISBN 13: 978-0415608459
Author:        David Hames

 

BIOS Instant Notes in Biochemistry, Fourth Edition, is the perfect text for undergraduates looking for a concise introduction to the subject, or a study guide to use before examinations. Each topic begins with a summary of essential facts-an ideal revision checklist-followed by a description of the subject that focuses on core information, with clear, simple diagrams that are easy for students to understand and recall in essays and exams.

BIOS Instant Notes in Biochemistry, Fourth Edition, is fully up-to-date and covers:

• Cells
• Amino acids and proteins
• Studying proteins
• Enzymes
• Membranes and cell signalling
• DNA structure and replication
• RNA synthesis and processing
• Protein synthesis
• Recombinant DNA technology
• Carbohydrate metabolism
• Lipid metabolism
• Respiration and energy
• Nitrogen metabolism

BIOS Instant Notes in Biochemistry 4th Table of contents:

Section A – Cells

• A1. Prokaryotic Cells: Overview of the structure and characteristics of prokaryotic cells, such as bacteria and archaea.
• A2. Eukaryotic Cells: Study of eukaryotic cells, including the structures and functions of organelles like the nucleus, mitochondria, and more.
• A3. Cell Growth: Discusses the process of cell division, growth, and regulation.
• A4. Cell Imaging: Techniques used to visualize cells, such as light microscopy, electron microscopy, and advanced imaging technologies.
• A5. Cell Fractionation: Methodologies for separating cellular components through centrifugation.

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Section B – Amino Acids and Proteins

• B1. Amino Acid Structure: Examination of the structure, types, and properties of amino acids.
• B2. Protein Structure and Function: Understanding protein structures (primary, secondary, tertiary, quaternary) and their biological roles.
• B3. Myoglobin and Hemoglobin: Study of these oxygen-binding proteins, their structure, and function in muscle and blood.
• B4. Collagen: Overview of collagen’s structure and its importance in connective tissues.
• B5. Molecular Motors: Exploration of proteins like myosin and kinesin that drive mechanical work in cells.
• B6. Antibodies: Structure, function, and role of antibodies in the immune response.

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Section C – Studying Proteins

• C1. Protein Purification: Techniques for isolating proteins from complex mixtures.
• C2. Gel Electrophoresis: Methods for separating proteins based on size and charge using electric fields.
• C3. Protein Sequencing and Peptide Synthesis: Approaches to determine protein sequences and synthesizing peptides.
• C4. Immunodetection: Techniques like Western blotting for detecting specific proteins using antibodies.

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Section D – Enzymes

• D1. Introduction to Enzymes: Basics of enzyme structure, function, and importance in catalyzing biochemical reactions.
• D2. Thermodynamics: Application of thermodynamic principles in enzyme catalysis.
• D3. Enzyme Kinetics: Study of the rate of enzyme-catalyzed reactions and factors influencing it.
• D4. Enzyme Inhibition: Mechanisms of how enzyme activity can be reduced or stopped.
• D5. Regulation of Enzyme Activity: Understanding how enzyme function is controlled in cells.

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Section E – Membranes and Cell Signaling

• E1. Membrane Lipids: Study of the structure and function of lipids in biological membranes.
• E2. Membrane Structure: Examination of the lipid bilayer and membrane proteins.
• E3. Membrane Transport: Small Molecules: Mechanisms of small molecule transport across membranes.
• E4. Membrane Transport: Macromolecules: Transport systems for larger molecules like proteins and polysaccharides.
• E5. Signal Transduction: Overview of how cells communicate through signaling pathways.
• E6. Nerve Function: The role of membranes and signaling in nerve cells and their communication.

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Section F – DNA Structure and Replication

• F1. An Introduction to DNA: Basics of DNA structure, including the double helix and nucleotide composition.
• F2. Genes and Chromosomes: How genes are organized into chromosomes and their role in heredity.
• F3. DNA Replication in Bacteria: The process of DNA replication in prokaryotes.
• F4. DNA Replication in Eukaryotes: DNA replication mechanisms in eukaryotic cells.

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Section G – RNA Synthesis and Processing

• G1. An Introduction to RNA: Basics of RNA structure and function.
• G2. Transcription in Prokaryotes: Mechanisms of RNA synthesis in bacteria.
• G3. Operons: Genetic regulation in prokaryotes through operons.
• G4. Transcription in Eukaryotes: An Overview: Overview of eukaryotic RNA transcription.
• G5. Transcription of Protein-Coding Genes in Eukaryotes: Detailed study of transcription in eukaryotic cells.
• G6. Regulation of Transcription by RNA Pol II: Control mechanisms for RNA polymerase II during transcription.
• G7. Processing of Eukaryotic Pre-mRNA: How eukaryotic pre-mRNA is processed before translation.
• G8. Transcription and Processing of Ribosomal RNA: How rRNA is synthesized and processed in cells.
• G9. Transcription and Processing of Transfer RNA: Processes involved in tRNA synthesis and maturation.

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Section H – Protein Synthesis

• H1. The Genetic Code: Understanding how DNA sequences code for proteins.
• H2. Translation in Prokaryotes: Overview of protein synthesis in bacteria.
• H3. Translation in Eukaryotes: Mechanisms of translation in eukaryotic cells.
• H4. Protein Targeting: How proteins are directed to specific cellular locations.
• H5. Protein Glycosylation: The process of adding sugar moieties to proteins for functional purposes.

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Section I – Recombinant DNA Technology

• I1. The Power of Recombinant DNA Approaches: Overview of how recombinant DNA technology has revolutionized biology.
• I2. Restriction Enzymes: The role of enzymes in cutting DNA at specific sequences.
• I3. Nucleic Acid Hybridization: Techniques for pairing complementary nucleic acid sequences.
• I4. DNA Cloning: Methods for creating copies of DNA sequences.
• I5. DNA Sequencing: Approaches to determine the sequence of nucleotides in DNA.
• I6. Polymerase Chain Reaction: A technique for amplifying specific DNA sequences.
• I7. Site-Directed Mutagenesis: Techniques for introducing specific mutations into DNA.

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Section J – Carbohydrate Metabolism

• J1. Monosaccharides and Disaccharides: Study of simple sugars and their properties.
• J2. Polysaccharides and Oligosaccharides: Structure and function of complex carbohydrates.
• J3. Glycolysis: The breakdown of glucose to generate ATP.
• J4. Gluconeogenesis: The process of synthesizing glucose from non-carbohydrate sources.
• J5. Pentose Phosphate Pathway: A metabolic pathway involved in the generation of nucleotides and NADPH.
• J6. Glycogen Metabolism: Study of glycogen synthesis and breakdown.
• J7. Control of Glycogen Metabolism: Regulation mechanisms for glycogen metabolism.

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Section K – Lipid Metabolism

• K1. Fatty Acid Structure and Function: The structure and biological importance of fatty acids.
• K2. Fatty Acid Breakdown: The process of fatty acid oxidation for energy production.
• K3. Fatty Acid Synthesis: The process of synthesizing fatty acids.
• K4. Triacylglycerols: The structure and role of triglycerides in energy storage.
• K5. Cholesterol: The structure and function of cholesterol in cellular membranes and as a precursor for hormones.
• K6. Lipoproteins: Study of complexes that transport lipids in the bloodstream.

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Section L – Respiration and Energy

• L1. Citric Acid Cycle: The cycle that generates ATP through the oxidation of acetyl-CoA.
• L2. Electron Transport and Oxidative Phosphorylation: Mechanisms of ATP production through the electron transport chain and oxidative phosphorylation.
• L3. Photosynthesis: The process by which plants convert light energy into chemical energy.

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Section M – Nitrogen Metabolism

• M1. Nitrogen Fixation and Assimilation: Conversion of atmospheric nitrogen into biologically usable forms.
• M2. Amino Acid Metabolism: The synthesis and breakdown of amino acids.
• M3. The Urea Cycle: The metabolic cycle that detoxifies ammonia in the liver.
• M4. Hemes and Chlorophylls: The role of heme in oxygen transport and chlorophyll in photosynthesis.

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