Biochemistry 3rd Edition by David Hames, Nigel Hooper ISBN 0415367786 9780415367783

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ISBN 10: 0415367786
ISBN 13: 9780415367783
Author: David Hames, Nigel Hooper

Biochemistry 3rd Edition Table of contents:

Chapter 1: Introduction to Biochemistry

• The Scope of Biochemistry
• The Structure and Function of Biomolecules
• The Central Dogma of Molecular Biology
• Biochemical Methodology and Techniques

Chapter 2: Water and pH

• The Structure and Properties of Water
• The Role of Water in Biochemical Reactions
• Acids, Bases, and pH in Biochemistry
• Buffers in Biological Systems

Chapter 3: Amino Acids and Proteins

• The Structure and Properties of Amino Acids
• Peptide Bond Formation and Protein Structure
• The Levels of Protein Structure: Primary, Secondary, Tertiary, and Quaternary
• Protein Folding and Stability
• Enzyme Catalysis and Kinetics

Chapter 4: Enzymes and Enzyme Kinetics

• Enzyme Structure and Mechanism of Action
• The Michaelis-Menten Model
• Enzyme Inhibition and Regulation
• Allosteric Enzymes and Cooperativity
• Enzyme Techniques in the Laboratory

Chapter 5: Nucleic Acids

• The Structure and Function of DNA and RNA
• DNA Replication, Transcription, and Translation
• The Genetic Code
• Gene Regulation and Expression
• Techniques for Analyzing Nucleic Acids

Chapter 6: Carbohydrates

• The Structure and Function of Simple Sugars and Polysaccharides
• Metabolism of Carbohydrates: Glycolysis, Gluconeogenesis, and the TCA Cycle
• The Pentose Phosphate Pathway
• Glycogen Storage and Metabolism
• Carbohydrate-Protein and Carbohydrate-Lipid Interactions

Chapter 7: Lipids

• The Structure and Classification of Lipids
• Fatty Acids and Their Role in Cellular Metabolism
• Membrane Lipids and Membrane Structure
• Lipid Metabolism: Fatty Acid Synthesis and Breakdown
• Lipoproteins and Their Role in Transport

Chapter 8: Bioenergetics

• The Principles of Thermodynamics in Biological Systems
• ATP as the Energy Currency of the Cell
• Oxidative Phosphorylation and the Electron Transport Chain
• The Role of Coenzymes and Prosthetic Groups in Energy Metabolism

Chapter 9: Metabolism of Carbohydrates

• Glycolysis: Pathway and Regulation
• The Citric Acid Cycle and Its Regulation
• The Pentose Phosphate Pathway
• Gluconeogenesis and Glycogen Metabolism
• Hormonal Regulation of Carbohydrate Metabolism

Chapter 10: Metabolism of Lipids

• Fatty Acid Oxidation: Beta-Oxidation Pathway
• Fatty Acid Synthesis and Regulation
• Ketone Bodies and Their Role in Metabolism
• Cholesterol and Lipid Transport
• Lipid Disorders and Disease

Chapter 11: Metabolism of Proteins and Amino Acids

• Amino Acid Metabolism and Deamination
• Urea Cycle and Ammonia Detoxification
• The Biosynthesis of Non-Essential Amino Acids
• Protein Turnover and Regulation
• Disorders of Amino Acid Metabolism

Chapter 12: Molecular Genetics and Biotechnology

• DNA Cloning and PCR Techniques
• Recombinant DNA Technology
• Genomics and Proteomics
• The Role of Biotechnology in Medicine and Industry

Chapter 13: Hormones and Signal Transduction

• Hormonal Regulation of Metabolism
• Receptors and Signal Transduction Pathways
• Second Messengers: cAMP, IP3, and Calcium
• Protein Kinases and Phosphatases
• The Role of Hormones in Growth, Development, and Disease

Chapter 14: Biochemical Basis of Disease

• The Genetic Basis of Disease
• Metabolic Disorders and Inborn Errors of Metabolism
• Cancer and Metabolic Reprogramming
• Disorders of Membrane Function and Transport
• Biochemical Approaches to Diagnosis and Therapy

Chapter 15: Experimental Techniques in Biochemistry

• Chromatography and Electrophoresis
• Spectroscopy and Mass Spectrometry
• NMR and X-ray Crystallography
• Enzyme Assays and Kinetic Analysis
• Molecular Biology Techniques: Cloning, Sequencing, and PCR

Chapter 16: Biochemistry of Cell Signaling and Regulation

• Cellular Signaling Mechanisms
• Signal Transduction Pathways and Their Regulation
• The Role of Protein Modifications: Phosphorylation, Acetylation, and Ubiquitination
• The Role of Cellular Stress and the Unfolded Protein Response

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