Aging and Age Related Disorders 2010th Edition by Stephen Bondy, Kenneth Maiese ISBN 1617796999 9781617796999

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ISBN 10: 1617796999 
ISBN 13: 9781617796999
Author: Stephen Bondy, Kenneth Maiese

Features that characterize the aging process include the gradual accumulation of cell damage after prolonged exposure to oxidative and inflammatory events over a lifetime. In addition to the accretion of lesions, the intrinsic levels of pro-oxidant and aberrant immune responses are elevated with age. These adverse events are often further enhanced by the chronic and slow progressing diseases that characterize the senescent brain and cardiovascular system. The incidence of some disorders such as Alzheimer’s disease and vascular diseases are sufficiently prevalent in the extreme elderly that these disorders can arguably be considered “normal”. Aging and Aging-Related Disorders examines the interface between normal and pathological aging, and illustrates how this border can sometimes be diffuse. It explores and illustrates the processes underlying the means by which aging becomes increasingly associated with inappropriate levels of free radical activity and how this can serve as a platform for the progression of age-related diseases. The book provides chapters that examine the interactive relationship between systems in the body that can enhance or sometimes even limit cellular longevity. In addition, specific redox mechanisms in cells are discussed. Another important aspect for aging discussed here is the close relationship between the systems of the body and exposure to environmental influences of oxidative stress that can affect both cellular senescence and a cell’s nuclear DNA. What may be even more interesting to note is that these external stressors are not simply confined to illnesses usually associated with aging, but can be evident in maturing and young individuals. A broad range of internationally recognized experts have contributed to this book. Their aim is to successfully highlight emerging knowledge and therapy for the understanding of the basis and development of aging–related disorders.

Aging and Age Related Disorders 2010th Table of contents:

1. Cellular Mechanisms of Aging

   • Cellular Senescence and Aging
   • DNA Damage and Repair
   • Telomere Shortening
   • Mitochondrial Dysfunction

2. Physiological Changes with Age

   • Cardiovascular System and Aging
   • Musculoskeletal System and Aging
   • Respiratory System in the Elderly
   • Neurobiology of Aging

3. Cognitive Decline and Dementia

   • Alzheimer’s Disease and Other Dementias
   • Pathophysiology and Diagnosis of Dementia
   • Treatment and Management of Cognitive Disorders
   • Cognitive Rehabilitation

4. Neurodegenerative Diseases

   • Parkinson’s Disease and Movement Disorders
   • Amyotrophic Lateral Sclerosis (ALS)
   • Huntington’s Disease
   • Multiple Sclerosis and Aging

5. Age-Related Cardiovascular Disorders

   • Hypertension and Age
   • Atherosclerosis and Cardiovascular Risk
   • Heart Failure and Aging
   • Stroke and Cerebrovascular Diseases

6. Osteoporosis and Bone Health

   • Pathophysiology of Osteoporosis
   • Fracture Risk and Prevention
   • Osteoarthritis in the Elderly
   • Treatment Approaches for Bone Loss

7. Endocrine Changes in Aging

   • Hormonal Changes in Aging: Men and Women
   • Diabetes and Aging
   • Thyroid Function and Aging
   • Osteoporosis and Hormonal Interactions

8. Sensory Decline and Aging

   • Vision Changes: Cataracts, Glaucoma, and Macular Degeneration
   • Hearing Loss and Auditory Processing
   • Taste and Smell Decline in the Elderly
   • Preventing Sensory Impairments

9. Age-Related Metabolic Changes

   • Altered Metabolism in the Elderly
   • Weight Loss and Malnutrition in Aging
   • Obesity and its Impact on Health
   • Managing Diabetes in Older Adults

10. Psychological and Social Aspects of Aging

    • Depression and Anxiety in the Elderly
    • Social Isolation and Loneliness
    • Coping with Loss and Grief
    • Elderly Care and Family Dynamics

11. Rehabilitation and Geriatric Care

    • Physiotherapy and Rehabilitation in Older Adults
    • Multidisciplinary Care Approaches
    • Palliative and End-of-Life Care
    • Aging in Place and Long-Term Care

12. Preventive Health and Aging

    • Preventive Healthcare for Older Adults
    • Immunization and Infection Control
    • Role of Diet and Exercise in Healthy Aging
    • Screening and Early Detection of Age-Related Disorders

13. Ethical Issues in Aging

    • Autonomy and Decision-Making in Older Adults
    • Elder Abuse and Safeguarding
    • Legal Aspects of Aging and Healthcare
    • End-of-Life Decisions and Ethics

14. Future Directions in Aging Research

    • Genetic and Epigenetic Research in Aging
    • Interventions and Therapies to Slow Aging
    • Anti-Aging Drugs and Clinical Trials
    • The Role of Technology in Managing Age-Related Disorders

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