Advances in Medical Biochemistry, Genomics, Physiology, and Pathology 1st edition By Raj Bawa, Esther Chang, Gerald Audette, Anil Diwan, Saadia Faiz – Ebook PDF Instant Download/Delivery. 9814877441 9789814877442
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ISBN 10: 9814877441
ISBN 13: 9789814877442
Author: Raj Bawa, Esther Chang, Gerald Audette, Anil Diwan, Saadia Faiz
The pace and sophistication of advances in medicine in the past two decades have necessitated a growing need for a comprehensive reference that highlights current issues in medicine. Each volume in the Current Issues in Medicine series is a standāalone text that provides a broad survey of various critical topics—all accomplished in a user-friendly yet interconnected format. The series not only highlights current advances but also explores related topics such as translational medicine, regulatory science, neglected diseases, global pandemics, patent law, immunotoxicology, theranostics, big data, artificial intelligence, novel imaging tools, combination drug products, and novel therapies. While bridging the gap between basic research and clinical medicine, this series provides a thorough understanding of medicine’s potential to address health problems from both the patient’s and the provider’s perspectives in a healthcare setting. The range of topics covered and the expertise of the contributing authors accurately reflect the rapidly evolving areas within medicine—from basic medical sciences to clinical specialties. Each volume is essential reading for physicians, medical students, nurses, fellows, residents, undergraduate and graduate students, educators, policymakers, and biomedical researchers. The multidisciplinary approach of the series makes it a valuable reference resource for the pharmaceutical industry, academia, and governments. However, unlike other series on medicine or medical textbooks, this series focuses on current trends, perspectives, and issues in medicine that are central to healthcare delivery in the 21st century. Volume 1 focuses on the current issues in basic medical sciences, subjects that are fundamental to the practice of medicine. Specifically, it covers medical biochemistry, genomics, physiology, and pathology. These subjects, traditionally taught in the first two years of medical school that precede clinical instruction, provide a core of basic knowledge critical to the success in clinical medicine during rotations, training, and medical practice.
Advances in Medical Biochemistry, Genomics, Physiology, and Pathology 1st Table of contents:
1. The Age of COVID-19: Medical Facts and Fiction
Raj Bawa, MS, PhD, MD’22
Section 1: Medical Biochemistry and Genomics
2. Role of Engineered Proteins as Therapeutic Formulations
Khushboo Gulati, PhD, and Krishna Mohan Poluri, PhD
3. How Physical and Chemical Information Predicts the Action of Molecules: A Historical Overview
Myron L. Toews, PhD, JoEllyn M. McMillan, PhD, and David B. Bylund, PhD
4. Three-Dimensional Chromatin in Infectious Disease: A Role for Gene Regulation and Pathogenicity?
Sage Z. Davis, PhD, Thomas Hollin, PhD, Todd Lenz, and Karine G. Le Roch, PhD
5. Aptamers, the Nucleic Acid Antibodies, in Cancer Therapy
Zhaoying Fu, PhD, and Jim Xiang, PhD
6. Identifying Genetic Markers Associated with Susceptibility to Cardiovascular Diseases
Hitesh Shukla, MSc, Jessica Louise Mason, MSc, and Abdullah Sabyah, MBBS, MSc
7. Production and Application of Multicistronic Constructs for Various Human Disease Therapies
Alisa A. Shaimardanova, Daria S. Chulpanova, Kristina V. Kitaeva, Ilmira I. Abdrakhmanova, Vladislav M. Chernov, DSc, Catrin S. Rutland, PhD, Albert A. Rizvanov, DSc, and Valeriya V. Solovyeva, PhD
8. The Nuclear Lamina: Protein Accumulation and Disease
Carla Almendáriz-Palacios, MSc, Zoe E. Gillespie, MSc, Matthew Janzen, Valeria Martinez, Joanna M. Bridger, PhD, Troy A. A. Harkness, PhD, Darrell D. Mousseau, PhD, and Christopher H. Eskiw, PhD
9. The Importance of Protein Post-Translational Modifications in the Pathogenesis and Progression of Neurodegenerative Diseases
Larissa-Nele Schaffert and Wayne G. Carter, PhD
10. DNA Damage/Repair Management in Cancers
Jehad F. Alhmoud, PhD, John F. Woolley, PhD, Ala-Eddin Al Moustafa, PhD, and Mohammed Imad Malki, MD, PhD
11. Advancing Clinical Cohort Selection with Genomics Analysis on a Distributed Platform
Jaclyn M. Smith, MSc, Melvin Lathara, MSc, Hollis Wright, PhD, Nalini Ganapati, MSc, Ganapati Srinivasa, MSc, and Christopher T. Denny, MD
12. Pharmacogenomics of Tamoxifen
Hitoshi Zembutsu, MD, PhD
13. Nanocrystals: The Universal Formulation Principle to Improve the Bioactivity of Poorly Soluble Actives
Ralph W. Eckert, Steffen F. Hartmann, Daniel Knoth, Olga Pelikh, Rainer H. Müller, PhD, and Cornelia M. Keck, PhD
14. Cellular Mechanisms of Human Atherogenesis: Focus on Chronification of Inflammation and Mitochondrial Mutations
Alexander M. Markin, PhD, Igor A. Sobenin, MD, PhD, Andrey V. Grechko, PhD, Dongwei Zhang, PhD, and Alexander N. Orkhov, PhD
15. Vitamin D Pathway and the Pathogenesis of Inflammatory Bowel Disease
Stefano Nobile, PhD, Michela A. Tenace, RN, and Helen M. Pappa, PhD
16. The Structural Ensemble of the Conjugative F-like T4SS
Nicholas Bragagnolo, MSc, Christina Rodriguez, and Gerald F. Audette, PhD
17. Polygenic Risk-Tailored Screening for Prostate Cancer: A Benefit–Harm and Cost-Effectiveness Modelling Study
Tom Callender, MBChB, MSc, Mark Emberton, MBBS, MD, Steve Morris, PhD, Ros Eeles, MBBS, PhD, Zsofia Kote-Jarai, PhD, Paul D. P. Pharoah, BM BCh, PhD, and Nora Pashayan, MD, PhD
18. Apoptotic Bodies: Particular Extracellular Vesicles Involved in Intercellular Communication
Michela Battistelli, PhD, and Elisabetta Falcieri, MD
Section 2: Human Physiology and Pathology
19. Circulating Tumor Cells and Personalized Medicine
Jin Sun Lee, MD, Mark Jesus M. Magbanua, PhD, Marc R. Jabon, MD, and John W. Park, MD
20. Pathology in the Era of Personalized Medicine
Hye Seung Lee, MD, PhD
21. Speech Intelligibility during Clinical and Low Frequency
John J. Sidtis, PhD, Diana Van Lancker Sidtis, PhD, Ritesh Ramdhani, MD, and Michele Tagliati, MD
22. Physiological Renormalization Using Systems Therapeutics
Greg Maguire, PhD
23. Pathology Is Always Around Us: Apophenia in Pathology, a Remarkable Unreported Phenomenon
Ahmed S. Sultan, BDS, PhD, and Maryam Jessri, DDS, PhD
24. The Secrets of the Mediterranean Diet. Does [Only] Olive Oil Matter?
Alessandra Mazzocchi, PhD, Ludovica Leone, PhD, Carlo Agostoni, PhD, and Isabella Pali-Schöll, PhD
25. Relationship between Diet, Microbiota, and Healthy Aging
Juan Gambini, PhD, Elisa Sanchez-Morate, MSc, Lucia Gimeno-Mallench, PhD, Kristine Stromsnes, MSc, Jorge Sanz-Ros, Aurora Román-Domínguez, MSc, Sergi Parejo-Pedrajas, MSc, Marta Inglés, PhD, Gloria Olaso, PhD, and Cristina Mas-Bargues, PhD
26. Does Low-Density Lipoprotein Cholesterol Induce Inflammation? If So, Does It Matter? Current Insights and Future Perspectives for Novel Therapies
Ruurt A. Jukema, MSc, Tarek A. N. Ahmed, MD, PhD, and Jean-Claude Tardif, MD
27. Role of Biomarkers in Clinical Development of Cancer Therapies
Helen X. Chen, MD
28. In Sickness and Health: Effects of Gut Microbial Metabolites on Human Physiology
Robert W. P. Glowacki, PhD, and Eric C. Martens, PhD
29. Current Methodologies Utilized in the Conduct of Randomized Clinical Trials
Marina A. Malikova, MSci, MA, PhD
30. The Prion-Like Phenomenon in Alzheimer’s Disease: Evidence of Pathology Transmission in Humans
Ruben Gomez-Gutierrez, PhD, and Rodrigo Morales, PhD
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