Adhesion in Pharmaceutical Biomedical and Dental Fields 1st edition by Etzler,Mittal 9781119323792 1119323797

Part 1: General Topics

Chapter 1: Theories and Mechanisms of Adhesion in the Pharmaceutical, Biomedical and Dental Fields

1.1 Introduction

1.2 Mechanisms of Adhesion

1.3 Summary

References

Chapter 2: Wettability of Powders

2.1 Introduction

2.2 Different Forms of Wetting

2.3 Hydrophilic and Hydrophobic Surfaces

2.4 Contact Angle Measurement in Wettability Studies of Powdered Materials

2.5 Contact Angle and Surface Free Energy

2.6 Surface Free Energy Determination of Powdered Solids by Thin Layer Wicking Method

2.7 Surface Free Energy Determination of Powdered Solids by Imbibition Drainage Method

2.8 Summary

Acknowledgement

References

Part 2: Adhesion in the Pharmaceutical Field

Chapter 3: Tablet Tensile Strength: Role of Surface Free Energy

3.1 Introduction

3.2 Applicability of the Proposed Model to Pharmaceutical Materials

3.3 Discussion

3.4 Summary

3.5 Acknowledgements

References

Chapter 4: Role of Surface Free Energy in Powder Behavior and Tablet Strength

4.1 Introduction

4.2 Surface Free Energy

4.3 Role of Surface Free Energy in Solid Wetting

4.4 Role of Surface Free Energy in Powder Flow

4.5 Role of Surface Free Energy in Powder Tableting

4.6 Concluding Remarks

References

Chapter 5: Mucoadhesive Polymers for Drug Delivery Systems

5.1 Introduction

5.2 Mucoadhesive Drug Delivery Systems

5.3 Mucoadhesive Polymers

5.4 Summary

References

Chapter 6: Transdermal Patches: An Overview

6.1 Introduction

6.2 Factors Affecting Skin Absorption

6.3 Passive Transdermal Drug Delivery Systems

6.4 Types, Structural Components and Materials Used to Design Passive TDDS

6.5 Active Transdermal Drug Delivery Systems

6.6 Production of Transdermal Patches

6.7 Biopharmaceutical Concerns

6.8 Pharmacokinetics of Transdermal Absorption

6.9 Manufacture, Design and Quality Control

6.10 Commercialized Patches

6.11 Regulatory Aspects

6.12 Summary and Future Prospects

Acknowledgement

References

Chapter 7: Film-Forming Technology and Skin Adhesion in Long-Wear Cosmetics

7.1 Introduction

7.2 Long-Wear Foundation: An overview

7.3 Effect of Skin Substrate on Adhesion

7.4 Long-Wear Technologies in Cosmetic Applications

7.5 Summary and Prospects

Acknowledgements

References

Part 3: Adhesion in the Biomedical Field

Chapter 8: Factors Affecting Microbial Adhesion

8.1 Introduction

8.2 Surface Characterization

8.3 Bacterial Adhesion to Material Surfaces

8.4 Summary

Acknowledgments

References

Chapter 9: Factors Influencing Biofouling and Use of Polymeric Materials to Mitigate It

9.1 Introduction

9.2 Origin of Biofouling

9.3 Prevention of Micro-Organisms Adhesion

9.4 Influence of Mechanical Properties

9.5 Influence of Surface Topography

9.6 Concluding Remarks

References

Chapter 10: Coatings on Surgical Tools and How to Promote Adhesion of Bio-Friendly Coatings on Their Surfaces

10.1 Introduction

10.2 Coatings on Various Surgical Tools and Implants in Different Fields of Operative Care to Patients

10.3 Promotion of Adhesion of Bio-Friendly Coatings on Surfaces of Tools and Implants

10.4 Summary

References

Chapter 11: Techniques for Deposition of Coatings with Enhanced Adhesion to Bio-Implants

11.1 Bio-Implants: An Introduction

11.2 Deposition Methods for Enhanced Adhesion of Coatings on Implants

11.3 Summary

References

Chapter 12: Relevance of Adhesion in Fabrication of Microarrays in Clinical Diagnostics

12.1 Introduction

12.2 Protein Microarrays

12.3 DNA Microarrays

12.4 Antibody Microarrays

12.5 Summary

References

Part 4: Adhesion in the Dental Field

Chapter 13: Antibacterial Polymers for Dental Adhesives and Composites

13.1 Introduction

13.2 Major Damage from Oral Biofilm Formed: The Acid Production

13.3 The Chemistry of Current Dental Adhesives and Composites

13.4 The Need for Treatments Targeting Oral Cariogenic Biofilms

13.5 Classification of Antibacterial Polymers for Dental Materials

13.6 Mechanisms of Action of Antibacterial Monomers

13.7 Antibacterial Properties of Dental Adhesives and Composites Containing Antibacterial Monomers

13.8 Considerations of Mechanical Properties

13.9 Summary and Prospects

Acknowledgments

Summary

Chapter 14: Dental Adhesives: From Earlier Products to Bioactive and Smart Materials

14.1 Introduction

14.2 Adhesion to Dental Substrates

14.3 Adhesive Strategies

14.4 Limitations in Bonding to Dental Substrates

14.5 Strategies to Reduce Bond Strength Degradation – Current Advances

14.6 Summary and Prospects

Acknowledgement

References

Chapter 15: Testing of Dental Adhesive Joints

15.1 Introduction

15.2 Various Bond Strength Tests

15.3 Summary