A Case-Based Guide to Neuromuscular Pathology 1st editon by Lan Zhou, Dennis Burns, Chunyu Cai – Ebook PDF Instant Download/Delivery. B07ZNSZ1Y9 978-3030256814
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Product details:
ISBN 10: B07ZNSZ1Y9
ISBN 13: 978-3030256814
Author: Lan Zhou, Dennis Burns, Chunyu Cai
This book provides a practical guide to the field of neuromuscular pathology including muscle, peripheral nerve, and skin biopsies with biopsy interpretation. Divided into three parts, the book begins with introductory chapters that review muscle, nerve, and skin biopsy indications and procedures, normal muscle and nerve histology, and common muscle and nerve pathology. The 28 myopathy case chapters in Part 2 and 11 neuropathy case chapters in Part 3 illustrate the clinical and pathological features of many neuromuscular diseases, demonstrate the indications and utilities of biopsies, discuss clinical and pathological differential diagnosis, update the individual disease management, and summarize pertinent clinical and pathology pearls for each case.
A Case-Based Guide to Neuromuscular Pathology will function as an indispensable reference for neurologists and pathologists looking to understand the utility of muscle, nerve, andskin biopsies. This book will also aid neurology residents, neuromuscular fellows and neuropathology fellows in preparing for questions related to the muscle and nerve pathology in their in-service and board exams.
A Case-Based Guide to Neuromuscular Pathology 1st Table of contents:
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Introduction to Neuromuscular Pathology
- Overview of the neuromuscular system: structure and function.
- General principles of neuromuscular diseases.
- Diagnostic approaches: clinical, histopathological, and molecular methods.
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Neuromuscular Disorders: An Overview
- Classification of neuromuscular diseases.
- Etiology, pathogenesis, and pathophysiology of neuromuscular disorders.
- Key diagnostic and therapeutic considerations.
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Case 1: Muscular Dystrophies
- Case study focusing on different types of muscular dystrophies (e.g., Duchenne, Becker, limb-girdle).
- Pathological features, genetic underpinnings, and diagnostic tools.
- Clinical manifestations and management.
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Case 2: Motor Neuron Diseases
- Case-based exploration of amyotrophic lateral sclerosis (ALS) and other motor neuron diseases.
- Pathology of motor neurons and related structures.
- Clinical progression and diagnostic challenges.
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Case 3: Myopathies
- Case studies on inflammatory and non-inflammatory myopathies (e.g., polymyositis, dermatomyositis).
- Muscle biopsy findings and immunohistochemistry in diagnosing myopathies.
- Clinical management and treatment options.
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Case 4: Peripheral Neuropathies
- Discussion of hereditary and acquired peripheral neuropathies (e.g., Guillain-Barré syndrome, Charcot-Marie-Tooth disease).
- Pathologic changes in peripheral nerves and diagnostic tests.
- Treatment approaches and prognosis.
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Case 5: Neuromuscular Junction Disorders
- Myasthenia gravis and other disorders affecting the neuromuscular junction.
- Case study on pathophysiology and diagnostic techniques.
- Immunological aspects and therapeutic strategies.
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Case 6: Congenital and Metabolic Neuromuscular Disorders
- Case-based approach to congenital neuromuscular disorders.
- Genetic causes, pathophysiology, and diagnostic challenges.
- Management of congenital neuromuscular disorders.
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Case 7: Neuromuscular Infections and Inflammatory Disorders
- Exploration of infectious causes of neuromuscular pathology (e.g., polio, viral myositis).
- Case studies on immune-mediated neuromuscular diseases.
- Diagnostic strategies and therapeutic considerations.
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Case 8: Tumors of the Neuromuscular System
- Case study on primary and secondary tumors affecting muscles and nerves.
- Histopathological features of neuromuscular tumors (e.g., schwannomas, neurofibromas).
- Clinical presentation and treatment options.
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Case 9: Neuromuscular Pathology in Systemic Diseases
- Neuromuscular manifestations of systemic diseases (e.g., diabetes, thyroid disease, rheumatoid arthritis).
- Pathological findings and case-based insights.
- Multidisciplinary approaches to management.
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Advanced Diagnostic Techniques in Neuromuscular Pathology
- Role of molecular pathology, genetic testing, and next-generation sequencing in neuromuscular diseases.
- Imaging techniques and their integration into diagnosis.
- Advances in tissue biopsy and histological analysis.
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Case 10: Emerging Neuromuscular Disorders
- Exploration of rare and newly discovered neuromuscular conditions.
- Case studies on diagnostic challenges and clinical management.
- The future of neuromuscular pathology in personalized medicine.
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Conclusion
- Summary of key learning points from the cases.
- Future directions in the diagnosis and treatment of neuromuscular diseases.
- Integrating case-based learning into clinical practice.
Appendices:
- Glossary of terms.
- Diagnostic resources and tables for neuromuscular pathology.
- Index of cases and conditions discussed.
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