Fetal and Neonatal Eye Pathology 1st edition by Robert Verdijk, Martina Herwig Carl ISBN 3030360784 978-3030360788

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Product details:

ISBN 10: 3030360784 
ISBN 13: 978-3030360788
Author: Robert Verdijk, Martina Herwig Carl 

This richly illustrated book discusses the fetal eye, offering a brief introduction to the topic and discussing its development and treatment. The high-quality reference images allow the morphological fetal age to be determined, and the authors provide examples of artifacts and real-world findings to simplify histopathological diagnosis. The book also discusses findings in fetal eyes, presenting typical examples of common malformations, including clinical and histological pictures as well as additional findings from other specialties (such as neuropathology, genetics). In addition, it covers non-specific ocular malformations. It particularly addresses documentation and interpretation of cases of suspected Shaken-Baby Syndrome, which is of forensic importance. In the context of retinopathy of prematurity, histopathological and clinical findings are correlated.

The book provides reference images of fetal development and guidelines on grossing and handling fetal eyes, andalso explores the complicated topic of artifacts, including case illustrations with comprehensive information concerning other specialties. Lastly it discusses clinically and forensically relevant findings in newborns. It guides ophthalmic and pediatric pathologists in the interpretation of ocular findings, helping to narrow down differential diagnoses in fetal pathology, while at the same time serving as a valuable tool for specialists who do not have a great deal of experience in the examination of fetal eyes.

Fetal and Neonatal Eye Pathology 1st Table of contents:

• Preface

  • Introduction to Fetal and Neonatal Eye Pathology
  • Importance of Early Diagnosis and Intervention
  • Overview of the Structure and Approach of the Text

• Chapter 1: Embryology and Development of the Eye

  • Development of the Ocular Structures: Cornea, Lens, Retina, and Optic Nerve
  • Genetic and Molecular Mechanisms of Eye Development
  • Developmental Milestones of the Fetal Eye

• Chapter 2: Pathological Mechanisms in Fetal and Neonatal Eye Diseases

  • Teratogenic Effects on the Developing Eye
  • Genetic Mutations and Syndromes Affecting the Eye
  • Intrauterine Infections and Their Impact on the Eye
  • Vascular and Structural Abnormalities in the Fetal Eye

• Chapter 3: Congenital Cataracts

  • Etiology and Pathogenesis of Congenital Cataracts
  • Genetic Causes and Syndromes Associated with Cataracts
  • Diagnosis and Management of Congenital Cataracts in Newborns

• Chapter 4: Retinopathy of Prematurity (ROP)

  • Pathophysiology of Retinopathy of Prematurity
  • Risk Factors and Staging of ROP
  • Clinical Management and Surgical Interventions
  • Long-Term Outcomes of ROP

• Chapter 5: Infections and Inflammatory Diseases

  • Intrauterine Infections: Cytomegalovirus (CMV), Toxoplasmosis, and Rubella
  • Neonatal Infections and Uveitis
  • Ophthalmic Manifestations of Systemic Infections in the Neonate

• Chapter 6: Congenital Glaucoma

  • Pathogenesis and Risk Factors for Congenital Glaucoma
  • Clinical Features and Diagnosis
  • Surgical and Medical Management of Neonatal Glaucoma

• Chapter 7: Retinal Abnormalities

  • Colobomas of the Retina and Optic Nerve
  • Retinal Dysplasias and Their Implications
  • Retinal Vascular Abnormalities in the Neonate

• Chapter 8: Anomalies of the Optic Nerve

  • Optic Nerve Hypoplasia and Its Causes
  • Inherited Disorders Affecting the Optic Nerve
  • Imaging and Diagnosis of Optic Nerve Anomalies

• Chapter 9: Ocular Tumors in the Fetus and Neonate

  • Retinoblastoma: Pathology and Genetics
  • Other Ocular Tumors in the Neonate
  • Diagnostic Imaging and Management

• Chapter 10: Genetic Syndromes with Ocular Manifestations

  • Syndromes with Ocular Involvement (e.g., Down Syndrome, Turner Syndrome, etc.)
  • Diagnosis and Genetic Counseling
  • Ocular Findings in Systemic Syndromes

• Chapter 11: Neonatal Screening and Early Diagnosis of Eye Pathologies

  • Vision Screening Techniques in the Neonate
  • Importance of Early Detection and Intervention
  • Role of Pediatric Ophthalmologists and Neonatologists in Diagnosis

• Chapter 12: Surgical and Medical Management of Fetal and Neonatal Eye Pathologies

  • Surgical Approaches in the Neonatal Period (e.g., Cataract Surgery, ROP Surgery)
  • Pharmacologic Interventions for Eye Conditions in Newborns
  • Multidisciplinary Approach to Management

• Chapter 13: Long-Term Prognosis and Follow-Up

  • Visual Development in Children with Neonatal Eye Disorders
  • Long-Term Care and Rehabilitation for Affected Infants
  • Psychological and Developmental Impact of Ocular Disorders

• Appendices

  • Glossary of Terms
  • Index
  • References and Suggested Further Reading

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