Oligodendroglioma Clinical Presentation Pathology Molecular Biology Imaging and Treatment 1st edition by Nina Paleologos, Herbert Newton ISBN 0128131586 978-0128131589

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ISBN 10: 0128131586
ISBN 13: 978-0128131589
Author: Nina Paleologos, Herbert Newton 

Oligodendroglioma: Clinical Presentation, Pathology, Molecular Biology, Imaging, and Treatment features the latest “cutting-edge” molecular biology, molecular therapeutics, imaging, immunotherapy, and research methods on the topic of oligodendrogliomas. The most detailed and comprehensive resource on the subject, it provides up-to-date information on clinical presentation, pathology, molecular biology, and treatment methods, including immunotherapy. This book is a critical for students, physicians and researchers in the fields of neuroscience, neuro-oncology, neurosurgery, radiation oncology, medical oncology, and others working in research or with patients.

• Provides the most up-to-date information regarding the clinical presentation, pathology, molecular biology, and methods for the treatment of oligodendroglioma brain tumors, including surgical therapy, radiotherapy, molecular therapeutics, chemotherapy, and immunotherapy
• Broadly appeals to anyone interested in the field of neuro-oncology and the treatment of patients with oligodendrogliomas
• Useful to clinicians interested in a thorough overview of the basic science and treatment of oligodendrogliomas
• Includes a section on immunotherapy, with updates on the use of vaccines and immune-based treatment approaches applied to oligodendrogliomas

Oligodendroglioma: Clinical Presentation, Pathology, Molecular Biology, Imaging, and Treatment 1st Table of contents:

• Introduction

  • Definition and Overview of Oligodendroglioma
  • Epidemiology and Prevalence

• Clinical Presentation

  • Symptoms and Signs
    • Seizures
    • Focal Neurological Deficits
    • Headaches
    • Cognitive and Personality Changes
  • Age and Gender Distribution
  • Clinical Course and Prognosis

• Pathology

  • Histological Features of Oligodendroglioma
    • Cellular Architecture
    • Classic “Fried Egg” Appearance
    • Microvascular Proliferation and Calcifications
  • Grading (WHO Classification)
  • Differential Diagnosis

• Molecular Biology

  • Genetic Alterations in Oligodendroglioma
    • IDH Mutations
    • 1p/19q Codeletion
  • Molecular Subtypes and Their Clinical Implications
  • Prognostic and Predictive Biomarkers

• Imaging

  • Radiologic Features on MRI and CT
    • Typical Findings (Contrast Enhancement, Calcifications, etc.)
    • Advanced Imaging Techniques (PET, Diffusion Tensor Imaging)
  • Role of Imaging in Diagnosis and Prognostication
  • Imaging Features in Relation to Molecular Markers

• Treatment

  • Surgical Resection
    • Goals and Challenges
    • Surgical Approach and Techniques
  • Radiotherapy
    • Indications and Techniques
    • Outcomes and Side Effects
  • Chemotherapy
    • Agents Used in Treatment
    • Chemotherapy in the Context of Molecular Markers
  • Emerging Therapies
    • Targeted Therapy and Immunotherapy
    • Clinical Trials and Novel Approaches

• Prognosis

  • Factors Influencing Prognosis
    • Molecular and Histological Markers
    • Surgical and Treatment Outcomes
  • Long-Term Follow-Up and Surveillance

• Conclusion

  • Summary of Key Concepts
  • Current Challenges and Future Directions

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