Pathology of lung disease morphology pathogenesis etiology 2nd edition by Helmut Popper ISBN 3030557421 978-3030557423

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ISBN 10: 3030557421 
ISBN 13: 978-3030557423
Author: Helmut Popper 

This well-illustrated book covers the full range of lung and pleural diseases from the pathologic standpoint. It has been updated from the first edition by including the most recent molecular data for the different lung diseases, tumor as well as non-tumor ones. New diagnostic tests are included, new aspects for the understanding of diseases have been added. Both diseases of adults and pediatric lung diseases are presented. The chapter on lung development has been expanded due to the many new findings being reported since the first edition.

The book will serve as an excellent guide to the diagnosis of these diseases, but in addition it explains the disease mechanisms and etiology. Genetics and molecular biology are also discussed whenever necessary for a full understanding. The author is an internationally recognized expert who runs courses on lung and pleural pathology attended by participants from all over the world. In compiling this book, he has drawn on more than 30 years’ experience in the field.

Pathology of lung disease morphology pathogenesis etiology 2nd Table of contents:

1. Introduction to Pulmonary Pathology

   • Overview of pulmonary anatomy and physiology.
   • Importance of studying lung disease and its impact on public health.
   • General principles of lung pathology: how diseases affect lung function.

2. Molecular and Cellular Pathogenesis

   • Cellular and molecular mechanisms of lung injury and repair.
   • Role of inflammation in lung diseases.
   • Pathophysiological mechanisms in acute and chronic lung conditions.

3. Pulmonary Infections

   • Bacterial, viral, fungal, and parasitic infections of the lungs.
   • Pathogenesis of pneumonia, tuberculosis, and fungal infections.
   • Immunological response to infections in the lungs.

4. Chronic Obstructive Pulmonary Disease (COPD)

   • Morphology and pathogenesis of COPD, including emphysema and chronic bronchitis.
   • Etiological factors, such as smoking and environmental exposures.
   • Mechanisms of airflow limitation and lung damage in COPD.

5. Interstitial Lung Diseases

   • Classification and pathology of interstitial lung diseases (ILDs), including idiopathic pulmonary fibrosis (IPF), sarcoidosis, and hypersensitivity pneumonitis.
   • Pathogenesis of lung fibrosis and the role of the immune system in ILDs.

6. Pulmonary Vascular Diseases

   • Pathology of pulmonary hypertension, pulmonary embolism, and vasculitis.
   • The role of blood vessels in lung diseases and their impact on gas exchange.
   • Genetic and environmental factors contributing to pulmonary vascular conditions.

7. Neoplastic Diseases of the Lung

   • Benign and malignant lung tumors, including lung carcinomas, small cell lung cancer (SCLC), and non-small cell lung cancer (NSCLC).
   • Genetic mutations and environmental exposures in lung cancer development.
   • Mechanisms of metastasis and tumor progression in the lungs.

8. Pneumoconioses and Occupational Lung Diseases

   • Pathology of diseases caused by exposure to industrial pollutants, asbestos, coal dust, and silica.
   • Etiology and pathogenesis of pneumoconioses like asbestosis, silicosis, and coal workers’ pneumoconiosis.
   • Occupational lung diseases and their long-term effects on lung health.

9. Environmental Lung Diseases

   • Impact of air pollution and climate change on lung diseases.
   • Allergic reactions and asthma as environmental contributors to lung pathology.
   • Role of environmental factors in the development of chronic respiratory conditions.

10. Pulmonary Disorders in Childhood

    • Pathology of lung diseases specific to pediatric populations, such as congenital lung diseases, bronchiolitis, and cystic fibrosis.
    • Etiological factors in pediatric lung diseases and their long-term consequences.

11. Genetic and Hereditary Lung Diseases

    • Genetic factors in lung diseases, such as cystic fibrosis, alpha-1 antitrypsin deficiency, and primary ciliary dyskinesia.
    • Inherited lung diseases and their pathophysiological mechanisms.

12. Pulmonary Fibrosis and Related Disorders

    • Mechanisms leading to pulmonary fibrosis and its various forms, including idiopathic pulmonary fibrosis and fibrotic lung diseases associated with autoimmune conditions.
    • Pathological features of fibrosis in the lungs and its impact on lung function.

13. Clinical and Radiologic Features of Lung Diseases

    • Radiologic techniques used in the diagnosis of lung diseases (CT scans, chest X-rays).
    • Correlation between pathological findings and clinical symptoms.
    • The role of pathology in guiding clinical management of lung diseases.

14. Advances in Lung Disease Research

    • New discoveries in the pathogenesis of lung diseases.
    • The future of personalized medicine and targeted therapies in the treatment of pulmonary diseases.
    • Advances in molecular diagnostics and therapies for lung diseases.

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