Pharmacology in Clinical Neurosciences A Quick Guide 1st edition by Hemanshu Prabhakar, Charu Mahajan, Indu Kapoor ISBN 9811535906 978-9811535901

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ISBN 10: 9811535906 
ISBN 13: 978-9811535901
Author: Hemanshu Prabhakar, Charu Mahajan, Indu Kapoor

The pharmacodynamics and pharmacokinetics of several drugs is expected to be known to clinicians and researchers at all times. With advances in sciences and development of newer drugs very frequently, it is very important to keep your knowledge updated at all times. This title is a quick guide to researchers and clinicians for a quick reference. The title is also a vital resource for all streams of neurosciences (neuroanesthesia and neurointensive care) and is much different from a conventional pharmacology titles, being more reader friendly and to the point facilitated with numerous flowcharts and algorithms with each chapter being prepared in a standard structured manner.

Pharmacology in Clinical Neurosciences A Quick Guide 1st Table of contents:

• Introduction to Clinical Neurosciences and Pharmacology
  • Overview of the nervous system and neurological diseases
  • The importance of pharmacology in treating neurological disorders
  • Drug targets in the central and peripheral nervous systems
• Pharmacokinetics in Neurosciences
  • Absorption, distribution, metabolism, and excretion of neuropharmacological agents
  • Blood-brain barrier (BBB) and its impact on drug delivery
  • Factors influencing the pharmacokinetics of neurological drugs
• Neurotransmitters and Their Receptors
  • The role of neurotransmitters (dopamine, serotonin, glutamate, GABA, etc.)
  • Mechanisms of neurotransmitter release, binding, and reuptake
  • Types of receptors involved in neurological drug actions (GABA receptors, dopaminergic receptors, etc.)
• Drugs in the Treatment of Psychiatric Disorders
  • Antidepressants: SSRIs, SNRIs, tricyclics, and MAO inhibitors
  • Antipsychotics: Typical vs atypical antipsychotics
  • Anxiolytics and sedatives: Benzodiazepines, non-benzodiazepines
  • Mood stabilizers: Lithium and anticonvulsants in psychiatric care
• Antiepileptic Drugs
  • Mechanisms of action of antiepileptic drugs (AEDs)
  • Commonly used AEDs: Phenytoin, valproate, lamotrigine, levetiracetam
  • Treatment strategies for different types of seizures (generalized, focal)
  • Management of status epilepticus
• Drugs for Neurodegenerative Diseases
  • Parkinson’s Disease: Dopaminergic drugs (levodopa, dopamine agonists), MAO-B inhibitors, COMT inhibitors
  • Alzheimer’s Disease: Acetylcholinesterase inhibitors (donepezil, rivastigmine), NMDA receptor antagonists
  • Drugs for other neurodegenerative disorders (Huntington’s disease, ALS)
• Pharmacological Management of Stroke
  • Acute ischemic stroke management: Thrombolytics (tPA), antiplatelet therapy
  • Hemorrhagic stroke management: Anticoagulant reversal, neurosurgery considerations
  • Secondary prevention strategies: Antithrombotic agents, blood pressure control
• Pain Management in Neurological Disorders
  • Pharmacological treatment of neuropathic pain
  • Opioids and non-opioid analgesics: Role in chronic pain
  • Anticonvulsants and antidepressants for neuropathic pain management
  • Topical agents and nerve blocks
• Drugs in the Treatment of Multiple Sclerosis
  • Immunomodulatory agents: Interferons, glatiramer acetate
  • Disease-modifying therapies: Natalizumab, fingolimod
  • Symptomatic treatments: Corticosteroids, muscle relaxants
• Drugs in Headache and Migraine Management
  • Acute treatment of migraine: Triptans, NSAIDs, antiemetics
  • Preventive treatment for migraine: Beta-blockers, anticonvulsants, CGRP inhibitors
  • Cluster headaches and tension-type headaches: Treatment approaches
• Neurological Anesthetics and Sedatives
  • General anesthetics: Inhalational agents, intravenous anesthetics
  • Local anesthetics: Mechanisms and clinical use
  • Sedative-hypnotics in neurological procedures
  • Neuromuscular blocking agents and their role in neurosurgery
• Pharmacology in Neuroinfections
  • Antibacterial, antiviral, and antifungal drugs for CNS infections
  • Treatment of bacterial meningitis, viral encephalitis, and brain abscesses
  • Antiretroviral drugs in HIV-associated neurological disorders
• Drugs for Neuromuscular Disorders
  • Anticholinesterase inhibitors for myasthenia gravis
  • Immunosuppressive drugs in autoimmune neuromuscular diseases
  • Botulinum toxin in the management of spasticity and dystonia
• Pharmacological Management of Sleep Disorders
  • Insomnia treatment: Sedative-hypnotics, melatonin, and alternatives
  • Pharmacotherapy for obstructive sleep apnea and narcolepsy
  • Drugs affecting circadian rhythms
• Side Effects and Adverse Reactions of Neurological Drugs
  • Common side effects: Cognitive dysfunction, sedation, weight gain
  • Drug interactions in neurology: Interaction between psychotropic and antiepileptic drugs
  • Managing adverse drug reactions in neurological care
• Pharmacogenomics in Neurological Disorders
  • Genetic factors influencing drug response in neurological diseases
  • Role of pharmacogenetics in tailoring drug therapy
  • Personalized medicine for psychiatric and neurodegenerative diseases
• Future Directions in Neuroscience Pharmacology
  • Emerging therapies and novel drug targets in neurology
  • Advances in gene therapy and stem cell treatment
  • The role of artificial intelligence in drug development for neurological diseases

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