Oral Microbiology and Immunology 2nd Edition by Richard J Lamont, George N Hajishengallis, Howard F Jenkinson ISBN 1555816738 9781555816735

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ISBN 10: 1555816738 
ISBN 13: 9781555816735
Author: Richard J Lamont, George N Hajishengallis, Howard F Jenkinson

In the second edition of best-selling textbook Oral Microbiology and Immunology, an international panel of editors presents an in-depth, comprehensive understanding of the oral ecosystem and its role in human health and disease. Written specifically for dental students, dental practitioners, and healthcare professionals, Oral Microbiology and Immunology cohesively details the ecology, virulence, molecular biology, and immunogenicity of oral bacteria, viruses, and fungi and examines their interfaces with host cells and secretions.

This new edition addresses the technological and conceptual advances that have increased our understanding of the etiology of oral diseases and the nature of pathogenic mechanisms and the host response, including:

• Genome sequencing of a bacterium or a community of bacteria.
• Knockout mice deficient in specific components of both the innate and adaptive immune systems.
• High-resolution and 3D imaging techniques of communities growing in biofilms and the intimate interactions between microbes and host cells.

Oral Microbiology and Immunology 2nd Table of contents:

Section 1: Introduction to Oral Microbiology

1. The Oral Ecosystem

   • The Oral Environment and Its Role in Health
   • Microbial Flora of the Oral Cavity
   • Host-Microbe Interactions in the Oral Cavity

2. Oral Microbial Diversity

   • Bacterial Taxonomy and Classification
   • Fungi, Viruses, and Protozoa in the Oral Cavity
   • Dynamics of Microbial Populations in the Mouth

3. Ecological Factors Affecting Oral Microbes

   • pH, Temperature, and Saliva Composition
   • Oral Hygiene, Diet, and Their Impact on Oral Microbes
   • Environmental Stressors and Microbial Adaptation

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Section 2: Oral Microbial Pathogenesis

4. Biofilm Formation and Function

   • The Concept of Biofilms in Oral Health and Disease
   • Formation, Development, and Maintenance of Biofilms
   • Microbial Communities in Dental Plaque

5. Periodontal Diseases and Microbial Etiology

   • Gingivitis and Periodontitis
   • Role of Bacteria in Periodontal Disease
   • Host Factors Influencing Periodontal Disease Progression

6. Dental Caries and Microbial Involvement

   • Etiology of Dental Caries
   • Cariogenic Bacteria and Their Mechanisms
   • The Role of Diet in Caries Development

7. Other Oral Infections

   • Oral Candidiasis and Fungal Infections
   • Viral Infections in the Oral Cavity
   • Oral Lesions and Their Pathogenesis

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Section 3: Oral Immunology

8. The Immune System in the Oral Cavity

   • Innate and Adaptive Immunity in the Oral Environment
   • The Role of Mucosal Immunity
   • Salivary Immunoglobulins and Other Protective Factors

9. Host Defense Mechanisms in the Oral Cavity

   • Epithelial Barriers and Antimicrobial Peptides
   • Immune Cell Populations in the Gingiva and Oral Mucosa
   • The Role of Cytokines in Oral Inflammation

10. Immunopathogenesis of Oral Diseases

    • Immune Responses in Periodontal Disease
    • Immune Responses to Dental Caries
    • Autoimmunity and Oral Manifestations

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Section 4: Clinical Implications and Oral Health

11. Diagnostic Techniques in Oral Microbiology

    • Methods for Identifying Oral Microbes
    • Molecular Diagnostics in Oral Pathogens
    • Immunological Approaches to Detecting Oral Diseases

12. Oral Disease Prevention and Control

    • Role of Oral Hygiene in Disease Prevention
    • Fluoride and Its Mechanisms of Action
    • Vaccines and Immunization in Oral Health

13. Oral Microbiome and Systemic Health

    • Link Between Oral Health and Systemic Diseases
    • Cardiovascular Disease, Diabetes, and Oral Infections
    • The Role of Oral Bacteria in Systemic Inflammation

14. Therapeutic Approaches to Oral Diseases

    • Antimicrobial Treatments for Oral Infections
    • Immunotherapy in Periodontal and Oral Cavity Diseases
    • Emerging Treatment Strategies and Clinical Trials

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